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Aliases for MIR550A1 Gene

Subcategory (RNA class) for MIR550A1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR550A1 Gene

  • MicroRNA 550a-1 2 3 5
  • MicroRNA 550-1 2 3
  • Hsa-Mir-550a-1 3
  • Hsa-Mir-550-1 3
  • Mir-550a-1 3
  • MIRN550-1 3
  • MIR550-1 3

External Ids for MIR550A1 Gene

ORGUL Members for MIR550A1 Gene

Previous HGNC Symbols for MIR550A1 Gene

  • MIRN550-1
  • MIR550-1

Summaries for MIR550A1 Gene

Entrez Gene Summary for MIR550A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR550A1 Gene

MIR550A1 (MicroRNA 550a-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR550A1 Gene

Genomics for MIR550A1 Gene

Regulatory Elements for MIR550A1 Gene

Enhancers for MIR550A1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F030344 1.5 FANTOM5 Ensembl ENCODE 13.2 +57.3 57327 6.2 TBP PKNOX1 CBX3 FEZF1 RAD21 ZBTB40 RFX5 CHAMP1 SCRT2 FOS ZNRF2 MIR550A1 NOD1 GC07P030343 ENSG00000281593
GH07F030158 1.6 FANTOM5 Ensembl ENCODE 12.1 -126.9 -126871 8.6 PKNOX1 ARID4B FEZF1 ZNF48 GATA2 FOS ZNF263 SP5 JUNB PPARG ZNRF2 MIR550A1 NOD1 MTURN LOC105375217 RPS27P16 ENSG00000251660
GH07F030168 1.5 FANTOM5 Ensembl ENCODE 12.1 -118.5 -118542 6.4 PKNOX1 ZFP64 INSM2 SIN3A FEZF1 RAD21 RARA FOS ZNF654 CEBPB ZNRF2 MIR550A1 NOD1 MTURN LOC105375217 GC07P030172 RPS27P16
GH07F030254 1.2 Ensembl ENCODE 11.9 -34.6 -34554 1.8 ELF3 ARID4B DMAP1 THRB ZSCAN9 RAD21 RARA YY1 ZNF366 CREM ZNRF2 MIR550A1 NOD1 LOC105375215 SCRN1 GC07M030247 LOC105375218
GH07F030350 0.8 Ensembl ENCODE 13.2 +61.4 61407 1.6 RNF2 PBX2 HMBOX1 MYC NR2F2 CHAMP1 MIR550A1 ZNRF2 NOD1 GC07P030343 ENSG00000281593
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR550A1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR550A1 Gene

Chromosome:
7
Start:
30,289,794 bp from pter
End:
30,289,890 bp from pter
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR550A1 Gene

Genes around MIR550A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR550A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR550A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR550A1 Gene

Proteins for MIR550A1 Gene

Post-translational modifications for MIR550A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR550A1 Gene

Domains & Families for MIR550A1 Gene

Gene Families for MIR550A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR550A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR550A1 Gene

Function for MIR550A1 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR550A1 Gene

Localization for MIR550A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR550A1 Gene

Pathways & Interactions for MIR550A1 Gene

SuperPathways for MIR550A1 Gene

No Data Available

Interacting Proteins for MIR550A1 Gene

Gene Ontology (GO) - Biological Process for MIR550A1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR550A1 Gene

Transcripts for MIR550A1 Gene

mRNA/cDNA for MIR550A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR550A1 Gene

No ASD Table

Relevant External Links for MIR550A1 Gene

GeneLoc Exon Structure for
MIR550A1
ECgene alternative splicing isoforms for
MIR550A1

Expression for MIR550A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR550A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR550A1 Gene:

MIR550A1
genes like me logo Genes that share expression patterns with MIR550A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR550A1 Gene

Orthologs for MIR550A1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR550A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-550-1 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR550A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR550A1 Gene

ENSEMBL:
Gene Tree for MIR550A1 (if available)
TreeFam:
Gene Tree for MIR550A1 (if available)

Paralogs for MIR550A1 Gene

No data available for Paralogs for MIR550A1 Gene

Variants for MIR550A1 Gene

Sequence variations from dbSNP and Humsavar for MIR550A1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs112033847 -- 30,289,903(+) CTCCA(A/G)TTTGA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112383221 -- 30,290,168(+) TAGTC(C/T)GTGTT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs113964452 -- 30,288,921(+) TTCCA(C/T)TGTCA intron-variant, upstream-variant-2KB
rs13232378 -- 30,287,993(+) GAAAT(A/C)TCTGT intron-variant, upstream-variant-2KB
rs13232559 -- 30,288,258(+) TATAT(A/C)CAAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR550A1 Gene

Variant ID Type Subtype PubMed ID
nsv1019527 CNV gain 25217958
nsv1068321 OTHER inversion 25765185
nsv1148830 OTHER inversion 26484159
nsv436557 CNV deletion 17901297
nsv981445 CNV duplication 23825009

Relevant External Links for MIR550A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR550A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR550A1 Gene

Disorders for MIR550A1 Gene

Relevant External Links for MIR550A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR550A1

No disorders were found for MIR550A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR550A1 Gene

Publications for MIR550A1 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  4. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 64

Products for MIR550A1 Gene

Sources for MIR550A1 Gene

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