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Aliases for MIR550A1 Gene

Subcategory (RNA class) for MIR550A1 Gene


Quality Score for this RNA gene is


Aliases for MIR550A1 Gene

  • MicroRNA 550a-1 2 3 5
  • MicroRNA 550-1 2 3
  • Hsa-Mir-550a-1 3
  • Hsa-Mir-550-1 3
  • Mir-550a-1 3
  • MIRN550-1 3
  • MIR550-1 3

External Ids for MIR550A1 Gene

ORGUL Members for MIR550A1 Gene

Previous HGNC Symbols for MIR550A1 Gene

  • MIRN550-1
  • MIR550-1

Summaries for MIR550A1 Gene

Entrez Gene Summary for MIR550A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR550A1 Gene

MIR550A1 (MicroRNA 550a-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR550A1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR550A1 Gene

Genomics for MIR550A1 Gene

GeneHancer (GH) Regulatory Elements for MIR550A1 Gene

Promoters and enhancers for MIR550A1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I030289 Enhancer 1 Ensembl ENCODE 550.8 +0.6 583 1.6 CTCF HDGF HDAC1 PKNOX1 SIN3A BATF ZNF507 ZNF335 GATA3 CBFA2T2 GC07P030289 MIR550A1 MIR550B1 DKFZP586I1420 ZNRF2 GC07P030343
GH07I030161 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 12.1 -125.2 -125238 5.4 PKNOX1 ARID4B FEZF1 YY1 TCF12 ZNF143 RUNX3 RXRA SP5 REST ZNRF2 MIR550A1 NOD1 MTURN LOC105375217 RPS27P16 ENSG00000251660
GH07I030347 Enhancer 1.4 FANTOM5 Ensembl ENCODE 13.2 +58.8 58847 3.2 PKNOX1 ATF1 SMAD1 NEUROD1 FEZF1 ZNF766 ZNF207 ATF7 FOS RUNX3 ZNRF2 MIR550A1 NOD1 GC07P030343 ENSG00000281593
GH07I030168 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12.1 -118.5 -118542 6.4 PKNOX1 INSM2 SIN3A FEZF1 RAD21 ZNF335 RCOR1 FOS ZNF654 CEBPB GC07P030172 ZNRF2 MIR550A1 NOD1 MTURN LOC105375217 RPS27P16
GH07I030158 Enhancer 1.2 Ensembl ENCODE dbSUPER 12.1 -129.9 -129907 2 SOX13 CTCF ESRRA KLF1 FOXA2 MAX ZNF48 RAD21 RARA CTBP1 MIR550A1 ZNRF2 NOD1 MTURN LOC105375217 ENSG00000251660 RPS27P16
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR550A1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR550A1 Gene

Genomic Locations for MIR550A1 Gene
97 bases
Plus strand

Genomic View for MIR550A1 Gene

Genes around MIR550A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR550A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR550A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR550A1 Gene

Proteins for MIR550A1 Gene

Post-translational modifications for MIR550A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR550A1 Gene

Domains & Families for MIR550A1 Gene

Gene Families for MIR550A1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR550A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR550A1 Gene

Function for MIR550A1 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR550A1 Gene

Localization for MIR550A1 Gene

Gene Ontology (GO) - Cellular Components for MIR550A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR550A1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR550A1 Gene

Pathways & Interactions for MIR550A1 Gene

SuperPathways for MIR550A1 Gene

No Data Available

Interacting Proteins for MIR550A1 Gene

Gene Ontology (GO) - Biological Process for MIR550A1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR550A1 Gene

Drugs & Compounds for MIR550A1 Gene

No Compound Related Data Available

Transcripts for MIR550A1 Gene

mRNA/cDNA for MIR550A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR550A1 Gene

No ASD Table

Relevant External Links for MIR550A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR550A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR550A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR550A1 Gene:

genes like me logo Genes that share expression patterns with MIR550A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR550A1 Gene

Orthologs for MIR550A1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR550A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-550-1 34
  • 100 (a)
Species where no ortholog for MIR550A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR550A1 Gene

Gene Tree for MIR550A1 (if available)
Gene Tree for MIR550A1 (if available)

Paralogs for MIR550A1 Gene

No data available for Paralogs for MIR550A1 Gene

Variants for MIR550A1 Gene

Sequence variations from dbSNP and Humsavar for MIR550A1 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000305971 -- 30,289,641(+) A/C upstream_transcript_variant
rs1003067457 -- 30,288,496(+) A/G upstream_transcript_variant
rs1003098637 -- 30,288,303(+) T/G upstream_transcript_variant
rs1003400076 -- 30,289,613(+) C/T upstream_transcript_variant
rs1003432885 -- 30,289,341(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR550A1 Gene

Variant ID Type Subtype PubMed ID
nsv1019527 CNV gain 25217958
nsv1068321 OTHER inversion 25765185
nsv1148830 OTHER inversion 26484159
nsv436557 CNV deletion 17901297
nsv981445 CNV duplication 23825009

Additional Variant Information for MIR550A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR550A1 Gene

Disorders for MIR550A1 Gene

Additional Disease Information for MIR550A1

No disorders were found for MIR550A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR550A1 Gene

Publications for MIR550A1 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  2. Micro RNA-550a interferes with vitamin D metabolism in peripheral B cells of patients with diabetes. (PMID: 27935135) He J … Yang S (Cell biochemistry and function 2016) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR550A1 Gene

Sources for MIR550A1 Gene

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