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Aliases for MIR548Z Gene

Subcategory (RNA class) for MIR548Z Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548Z Gene

  • MicroRNA 548z 2 3
  • Hsa-Mir-548c 5
  • Hsa-Mir-548z 3

External Ids for MIR548Z Gene

Previous GeneCards Identifiers for MIR548Z Gene

  • GC12U901505
  • GC12M065017

Summaries for MIR548Z Gene

Entrez Gene Summary for MIR548Z Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548Z Gene

MIR548Z (MicroRNA 548z) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548Z Gene

Genomics for MIR548Z Gene

Regulatory Elements for MIR548Z Gene

Enhancers for MIR548Z Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR548Z on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548Z Gene

Chromosome:
12
Start:
64,622,509 bp from pter
End:
64,622,605 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR548Z Gene

Genes around MIR548Z on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548Z Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548Z Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548Z Gene

ORGUL Member Location for MIR548Z Gene

ORGUL Member Location for MIR548Z gene

Proteins for MIR548Z Gene

Post-translational modifications for MIR548Z Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548Z Gene

Domains & Families for MIR548Z Gene

Gene Families for MIR548Z Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548Z: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548Z Gene

Function for MIR548Z Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548Z Gene

Localization for MIR548Z Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548Z Gene

Pathways & Interactions for MIR548Z Gene

SuperPathways for MIR548Z Gene

No Data Available

Interacting Proteins for MIR548Z Gene

Gene Ontology (GO) - Biological Process for MIR548Z Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548Z Gene

Drugs & Compounds for MIR548Z Gene

No Compound Related Data Available

Transcripts for MIR548Z Gene

mRNA/cDNA for MIR548Z Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548Z Gene

No ASD Table

Relevant External Links for MIR548Z Gene

GeneLoc Exon Structure for
MIR548Z
ECgene alternative splicing isoforms for
MIR548Z

Expression for MIR548Z Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548Z Gene:

MIR548Z
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548Z Gene

Orthologs for MIR548Z Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548Z Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 80 (a)
ManyToMany
Species where no ortholog for MIR548Z was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548Z Gene

ENSEMBL:
Gene Tree for MIR548Z (if available)
TreeFam:
Gene Tree for MIR548Z (if available)

Paralogs for MIR548Z Gene

No data available for Paralogs for MIR548Z Gene

Variants for MIR548Z Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548Z Gene

Variant ID Type Subtype PubMed ID
dgv2682n54 CNV gain 21841781
nsv832443 CNV loss 17160897
nsv832444 CNV loss 17160897

Relevant External Links for MIR548Z Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548Z

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR548Z Gene

Disorders for MIR548Z Gene

Relevant External Links for MIR548Z

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548Z

No disorders were found for MIR548Z Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548Z Gene

Publications for MIR548Z Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 65
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 65

Products for MIR548Z Gene

Sources for MIR548Z Gene

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