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Aliases for MIR548X Gene

Subcategory (RNA class) for MIR548X Gene


Quality Score for this RNA gene is


Aliases for MIR548X Gene

  • MicroRNA 548x 2 3 5
  • Hsa-Mir-548x 3

External Ids for MIR548X Gene

Previous GeneCards Identifiers for MIR548X Gene

  • GC21U900384
  • GC21M020060

Summaries for MIR548X Gene

Entrez Gene Summary for MIR548X Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548X Gene

MIR548X (MicroRNA 548x) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548X Gene

Genomics for MIR548X Gene

Regulatory Elements for MIR548X Gene

Enhancers for MIR548X Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21F018666 0.2 ENCODE 0.3 +19.1 19091 0.8 MIR548X ENSG00000230233
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548X on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548X Gene

18,686,090 bp from pter
18,686,164 bp from pter
75 bases
Minus strand

Genomic View for MIR548X Gene

Genes around MIR548X on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548X Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548X Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548X Gene

ORGUL Member Location for MIR548X Gene

ORGUL Member Location for MIR548X gene

Proteins for MIR548X Gene

Post-translational modifications for MIR548X Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548X Gene

Domains & Families for MIR548X Gene

Gene Families for MIR548X Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548X: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548X Gene

Function for MIR548X Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548X Gene

Localization for MIR548X Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548X Gene

Pathways & Interactions for MIR548X Gene

SuperPathways for MIR548X Gene

No Data Available

Interacting Proteins for MIR548X Gene

Gene Ontology (GO) - Biological Process for MIR548X Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548X Gene

Transcripts for MIR548X Gene

mRNA/cDNA for MIR548X Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548X Gene

No ASD Table

Relevant External Links for MIR548X Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548X Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548X Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548X Gene

Orthologs for MIR548X Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548X Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 35
  • 100 (a)
Species where no ortholog for MIR548X was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548X Gene

Gene Tree for MIR548X (if available)
Gene Tree for MIR548X (if available)

Paralogs for MIR548X Gene

No data available for Paralogs for MIR548X Gene

Variants for MIR548X Gene

Sequence variations from dbSNP and Humsavar for MIR548X Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1041409 -- 18,687,308(+) CATGT(A/G)ATTCT intron-variant, upstream-variant-2KB
rs113294021 -- 18,685,592(+) TCTGC(A/G)TTCAC intron-variant, downstream-variant-500B
rs113579204 -- 18,686,405(+) TCCAA(A/G)ACTCC intron-variant, upstream-variant-2KB
rs114438358 -- 18,685,944(+) ATGAG(A/G)AAGAT intron-variant, downstream-variant-500B
rs114966636 -- 18,686,673(+) AAGAG(A/G)TATAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548X Gene

Variant ID Type Subtype PubMed ID
dgv4392n100 CNV gain 25217958
dgv4393n100 CNV gain 25217958
dgv524n27 CNV gain 19166990
dgv525n27 CNV gain 19166990
dgv7779n54 CNV gain 21841781
dgv7780n54 CNV gain 21841781
dgv7781n54 CNV gain 21841781
dgv7782n54 CNV gain 21841781
esv2421672 CNV duplication 20811451
esv2751925 CNV loss 17911159
esv2763677 CNV gain 21179565
esv3646502 CNV gain 21293372
esv3893384 CNV gain 25118596
nsv517044 CNV gain 19592680
nsv587141 CNV gain 21841781

Relevant External Links for MIR548X Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548X Gene

Disorders for MIR548X Gene

Relevant External Links for MIR548X

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548X Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548X Gene

Publications for MIR548X Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548X Gene

Sources for MIR548X Gene

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