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Aliases for MIR548W Gene

Subcategory (RNA class) for MIR548W Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548W Gene

  • MicroRNA 548w 2 3 5
  • Hsa-Mir-548w 3

External Ids for MIR548W Gene

Previous GeneCards Identifiers for MIR548W Gene

  • GC16U901207

Summaries for MIR548W Gene

Entrez Gene Summary for MIR548W Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548W Gene

MIR548W (MicroRNA 548w) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548W Gene

Genomics for MIR548W Gene

Regulatory Elements for MIR548W Gene

Enhancers for MIR548W Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F026002 0.9 FANTOM5 0.3 -22.3 -22307 0.1 HS3ST4 GC16P025982 MIR548W
GH16F026004 0.7 FANTOM5 0.3 -20.3 -20309 0.1 GC16P025982 MIR548W
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548W on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548W Gene

Chromosome:
16
Start:
26,025,237 bp from pter
End:
26,025,310 bp from pter
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR548W Gene

Genes around MIR548W on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548W Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548W Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548W Gene

Proteins for MIR548W Gene

Post-translational modifications for MIR548W Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548W Gene

Domains & Families for MIR548W Gene

Gene Families for MIR548W Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548W: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548W Gene

Function for MIR548W Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548W Gene

Localization for MIR548W Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548W Gene

Pathways & Interactions for MIR548W Gene

SuperPathways for MIR548W Gene

No Data Available

Interacting Proteins for MIR548W Gene

Gene Ontology (GO) - Biological Process for MIR548W Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548W Gene

Transcripts for MIR548W Gene

mRNA/cDNA for MIR548W Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548W Gene

No ASD Table

Relevant External Links for MIR548W Gene

GeneLoc Exon Structure for
MIR548W
ECgene alternative splicing isoforms for
MIR548W

Expression for MIR548W Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548W Gene:

MIR548W
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548W Gene

Orthologs for MIR548W Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548W Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 99 (a)
OneToOne
Species where no ortholog for MIR548W was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548W Gene

ENSEMBL:
Gene Tree for MIR548W (if available)
TreeFam:
Gene Tree for MIR548W (if available)

Paralogs for MIR548W Gene

No data available for Paralogs for MIR548W Gene

Variants for MIR548W Gene

Sequence variations from dbSNP and Humsavar for MIR548W Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs113273703 -- 26,023,529(+) CAAGT(A/C)GCTAG intron-variant, upstream-variant-2KB
rs114241236 -- 26,025,372(+) CGTAC(A/G)CTGGG intron-variant, downstream-variant-500B
rs114543669 -- 26,025,359(+) TTACC(A/G)TTTCA intron-variant, downstream-variant-500B
rs114675343 -- 26,023,634(+) CTCCC(A/G/T)GCCTC intron-variant, upstream-variant-2KB
rs115665020 -- 26,025,774(+) TGTTC(A/C)TTTGT intron-variant, downstream-variant-500B

Relevant External Links for MIR548W Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548W

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548W Gene

Disorders for MIR548W Gene

Relevant External Links for MIR548W

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548W

No disorders were found for MIR548W Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548W Gene

Publications for MIR548W Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548W Gene

Sources for MIR548W Gene

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