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Aliases for MIR548V Gene

Subcategory (RNA class) for MIR548V Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548V Gene

  • MicroRNA 548v 2 3 5
  • Hsa-Mir-548v 3

External Ids for MIR548V Gene

Previous GeneCards Identifiers for MIR548V Gene

  • GC08U901463
  • GC08M017539

Summaries for MIR548V Gene

Entrez Gene Summary for MIR548V Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548V Gene

MIR548V (MicroRNA 548v) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548V Gene

Genomics for MIR548V Gene

Regulatory Elements for MIR548V Gene

Enhancers for MIR548V Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08G017684 0.9 ENCODE dbSUPER 0.7 -2.5 -2527 0.3 ZNF263 CTCF PRDM6 BCL6B ZNF341 REPIN1 PRDM10 SPI1 MIR548V GC08M017697
GH08G017672 1.5 Ensembl ENCODE dbSUPER 0.4 +6.6 6637 5.4 ATF1 PKNOX1 SIN3A FEZF1 ZNF2 YY1 TCF12 ZNF121 ZNF766 ELK1 PDGFRL MTUS1 MIR548V ENSG00000277466
GH08G017658 1.5 Ensembl ENCODE dbSUPER 0.4 +18.9 18917 9.0 FOXA2 ARID4B FEZF1 ZNF48 YY1 GATA2 FOS ZNF263 REST PPARG ENSG00000253168 MTUS1 MIR548V ENSG00000277466
GH08G017693 1.2 Ensembl ENCODE dbSUPER 0.4 -14.2 -14155 4.8 ATF1 JUN MAX ZIC2 ATF2 RAD21 ATF3 CBX5 POLR2A EED PDGFRL MTUS1 GC08M017697 MIR548V
GH08G017691 1.2 Ensembl ENCODE dbSUPER 0.4 -10.4 -10366 1.6 BHLHE40 MAX USF2 CHD7 ZNF354B GABPA RAD51 POLR2A ZSCAN5C ZBTB20 PDGFRL GC08M017697 MIR548V
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548V on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548V Gene

Chromosome:
8
Start:
17,681,578 bp from pter
End:
17,681,657 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR548V Gene

Genes around MIR548V on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548V Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548V Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548V Gene

Proteins for MIR548V Gene

Post-translational modifications for MIR548V Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548V Gene

Domains & Families for MIR548V Gene

Gene Families for MIR548V Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548V: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548V Gene

Function for MIR548V Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548V Gene

Localization for MIR548V Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548V Gene

Pathways & Interactions for MIR548V Gene

SuperPathways for MIR548V Gene

No Data Available

Interacting Proteins for MIR548V Gene

Gene Ontology (GO) - Biological Process for MIR548V Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548V Gene

Drugs & Compounds for MIR548V Gene

No Compound Related Data Available

Transcripts for MIR548V Gene

mRNA/cDNA for MIR548V Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548V Gene

No ASD Table

Relevant External Links for MIR548V Gene

GeneLoc Exon Structure for
MIR548V
ECgene alternative splicing isoforms for
MIR548V

Expression for MIR548V Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548V Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548V Gene:

MIR548V
genes like me logo Genes that share expression patterns with MIR548V: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548V Gene

Orthologs for MIR548V Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548V Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 99 (a)
OneToOne
Species where no ortholog for MIR548V was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548V Gene

ENSEMBL:
Gene Tree for MIR548V (if available)
TreeFam:
Gene Tree for MIR548V (if available)

Paralogs for MIR548V Gene

No data available for Paralogs for MIR548V Gene

Variants for MIR548V Gene

Sequence variations from dbSNP and Humsavar for MIR548V Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1000844890 -- 17,681,230(+) CGCCC(A/C/G)GCCTG intron-variant, downstream-variant-500B
rs1001176146 -- 17,683,576(+) CATGA(A/G)CCACA intron-variant, upstream-variant-2KB
rs1002981984 -- 17,683,017(+) CCTGT(A/T)ATCCC intron-variant, upstream-variant-2KB
rs1006004044 -- 17,683,462(+) GTTTT(A/C)TTTTT intron-variant, upstream-variant-2KB
rs1006469059 -- 17,683,544(+) TCCTC(A/G)TCTTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548V Gene

Variant ID Type Subtype PubMed ID
esv2759600 CNV loss 17122850
esv34867 CNV loss 17911159
esv3616489 CNV loss 21293372
esv3616492 CNV loss 21293372
nsv831247 CNV gain 17160897
nsv831249 CNV loss 17160897

Relevant External Links for MIR548V Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548V

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548V Gene

Disorders for MIR548V Gene

Relevant External Links for MIR548V

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548V

No disorders were found for MIR548V Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548V Gene

Publications for MIR548V Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548V Gene

Sources for MIR548V Gene

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