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Aliases for MIR548T Gene

Subcategory (RNA class) for MIR548T Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548T Gene

  • MicroRNA 548t 2 3 5
  • Hsa-Mir-548t 3

External Ids for MIR548T Gene

Previous GeneCards Identifiers for MIR548T Gene

  • GC04U901359
  • GC04P165301
  • GC04P174191

Summaries for MIR548T Gene

Entrez Gene Summary for MIR548T Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548T Gene

MIR548T (MicroRNA 548t) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548T Gene

Genomics for MIR548T Gene

Regulatory Elements for MIR548T Gene

Enhancers for MIR548T Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04G173241 0.9 ENCODE dbSUPER 11 -24.9 -24855 2.6 INSM2 GATAD2B EBF1 NR2F2 OSR2 JUND PRDM6 FOS ZBTB33 WT1 MIR548T LOC101930370 GALNT7
GH04G173246 0.6 dbSUPER 11.2 -21.0 -20975 3.7 OSR2 PRDM6 SMARCA4 MLLT1 FEZF1 SPI1 MIR548T LOC101930370
GH04G173245 0.2 dbSUPER 11 -22.1 -22120 0.7 MIR548T LOC101930370
GH04G173263 1.3 Ensembl ENCODE dbSUPER 0.7 -3.4 -3419 1.7 HDAC1 CBX3 TAL1 SIN3A FEZF1 ZKSCAN1 TCF12 POLR2A GATA2 NCOR1 SCRG1 MIR548T LOC101930370
GH04G173249 1.6 Ensembl ENCODE dbSUPER 0.4 -16.4 -16378 4.1 PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZNF766 FOS SP3 JUNB REST MIR548T LOC101930370
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548T on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548T Gene

Chromosome:
4
Start:
173,268,160 bp from pter
End:
173,268,233 bp from pter
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR548T Gene

Genes around MIR548T on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548T Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548T Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548T Gene

Proteins for MIR548T Gene

Post-translational modifications for MIR548T Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548T Gene

Domains & Families for MIR548T Gene

Gene Families for MIR548T Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548T: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548T Gene

Function for MIR548T Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548T Gene

Localization for MIR548T Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548T Gene

Pathways & Interactions for MIR548T Gene

SuperPathways for MIR548T Gene

No Data Available

Interacting Proteins for MIR548T Gene

Gene Ontology (GO) - Biological Process for MIR548T Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548T Gene

Transcripts for MIR548T Gene

mRNA/cDNA for MIR548T Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548T Gene

No ASD Table

Relevant External Links for MIR548T Gene

GeneLoc Exon Structure for
MIR548T
ECgene alternative splicing isoforms for
MIR548T

Expression for MIR548T Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548T Gene:

MIR548T
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548T Gene

Orthologs for MIR548T Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548T Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 99 (a)
OneToOne
Species where no ortholog for MIR548T was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548T Gene

ENSEMBL:
Gene Tree for MIR548T (if available)
TreeFam:
Gene Tree for MIR548T (if available)

Paralogs for MIR548T Gene

No data available for Paralogs for MIR548T Gene

Variants for MIR548T Gene

Sequence variations from dbSNP and Humsavar for MIR548T Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1001903108 -- 173,267,994(+) CTCTT(C/T)ATTGT intron-variant, upstream-variant-2KB
rs1003169738 -- 173,266,327(+) TTGGT(A/T)CTGTG intron-variant, upstream-variant-2KB
rs1003739311 -- 173,266,195(+) GCGGA(C/T)GTTGC intron-variant, upstream-variant-2KB
rs1006708787 -- 173,268,715(+) TTTGT(A/G/T)TTTTT intron-variant, downstream-variant-500B
rs1007974109 -- 173,267,492(+) ATGCC(C/T)GGGCA intron-variant, upstream-variant-2KB

Relevant External Links for MIR548T Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548T

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548T Gene

Disorders for MIR548T Gene

Relevant External Links for MIR548T

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548T

No disorders were found for MIR548T Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548T Gene

Publications for MIR548T Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. Re-inspection of small RNA sequence datasets reveals several novel human miRNA genes. (PMID: 20532037) Hansen T.B. … Kjems J. (PLoS ONE 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548T Gene

Sources for MIR548T Gene

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