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Aliases for MIR548S Gene

Subcategory (RNA class) for MIR548S Gene


Quality Score for this RNA gene is


Aliases for MIR548S Gene

  • MicroRNA 548s 2 3 5
  • Hsa-Mir-548s 3

External Ids for MIR548S Gene

Previous GeneCards Identifiers for MIR548S Gene

  • GC02U902080
  • GC02P011907

Summaries for MIR548S Gene

Entrez Gene Summary for MIR548S Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548S Gene

MIR548S (MicroRNA 548s) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548S Gene

Genomics for MIR548S Gene

Regulatory Elements for MIR548S Gene

Enhancers for MIR548S Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F011764 0.2 ENCODE 0.8 -2.9 -2865 0.1 PKNOX1 NFIA SAP130 ARID4B SIN3A MXD4 MNT DPF2 REST RAD21 LOC101929752 LPIN1 GC02M011761 MIR548S
GH02F011774 0.9 Ensembl ENCODE 0.4 +7.9 7943 1.7 HDGF LEF1 MXI1 TAL1 CEBPG FOSL1 NCOR1 SCRT2 SMARCE1 CEBPB LPIN1 ENSG00000230790 LOC100506405 LOC101929752 MIR548S LOC105373430
GH02F011778 0.6 Ensembl ENCODE 0.4 +11.5 11540 1.9 ELF3 HDAC1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF48 RAD21 GLIS2 LPIN1 ENSG00000230790 LOC101929752 LOC100506405 NTSR2 CDK8P1 MIR548S LOC105373430
GH02F011777 0.5 ENCODE 0.4 +10.1 10062 0.4 MAX MYC LPIN1 ENSG00000230790 LOC100506405 LOC101929752 MIR548S LOC105373430
GH02F011784 1.3 Ensembl ENCODE 0.3 +17.5 17544 0.7 HDGF SOX13 BCOR CTCF KLF1 ZMYM3 ZNF48 ZNF644 RAD21 ADNP LPIN1 ENSG00000230790 LOC101929752 LOC100506405 MIR548S LOC105373430
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548S on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548S Gene

11,767,444 bp from pter
11,767,525 bp from pter
82 bases
Plus strand

Genomic View for MIR548S Gene

Genes around MIR548S on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548S Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548S Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548S Gene

Proteins for MIR548S Gene

Post-translational modifications for MIR548S Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548S Gene

Domains & Families for MIR548S Gene

Gene Families for MIR548S Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548S: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548S Gene

Function for MIR548S Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548S Gene

Localization for MIR548S Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548S Gene

Pathways & Interactions for MIR548S Gene

SuperPathways for MIR548S Gene

No Data Available

Interacting Proteins for MIR548S Gene

Gene Ontology (GO) - Biological Process for MIR548S Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548S Gene

Transcripts for MIR548S Gene

mRNA/cDNA for MIR548S Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548S Gene

No ASD Table

Relevant External Links for MIR548S Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548S Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR548S Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548S Gene:

genes like me logo Genes that share expression patterns with MIR548S: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548S Gene

Orthologs for MIR548S Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548S Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 35
  • 100 (a)
Species where no ortholog for MIR548S was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548S Gene

Gene Tree for MIR548S (if available)
Gene Tree for MIR548S (if available)

Paralogs for MIR548S Gene

No data available for Paralogs for MIR548S Gene

Variants for MIR548S Gene

Sequence variations from dbSNP and Humsavar for MIR548S Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10209969 Benign 11,765,750(+) GGGCA(C/T)GGGGA intron-variant, upstream-variant-2KB
rs45509591 Benign 11,767,716(+) CCTGT(C/T)CTGGT intron-variant, downstream-variant-500B
rs75259222 Benign 11,767,720(+) TCCTG(G/T)TGAAG intron-variant, downstream-variant-500B
rs111943416 -- 11,765,545(+) CCATG(A/G)ATTAC upstream-variant-2KB, reference, missense
rs112310417 -- 11,766,768(+) ACAAA(A/C)ACAAA intron-variant, upstream-variant-2KB

Relevant External Links for MIR548S Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548S Gene

Disorders for MIR548S Gene

Relevant External Links for MIR548S

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548S Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548S Gene

Publications for MIR548S Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548S Gene

Sources for MIR548S Gene

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