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Aliases for MIR548S Gene

Subcategory (RNA class) for MIR548S Gene


Quality Score for this RNA gene is


Aliases for MIR548S Gene

  • MicroRNA 548s 2 3 5
  • Hsa-Mir-548s 3

External Ids for MIR548S Gene

Previous GeneCards Identifiers for MIR548S Gene

  • GC02U902080
  • GC02P011907

Summaries for MIR548S Gene

Entrez Gene Summary for MIR548S Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548S Gene

MIR548S (MicroRNA 548s) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548S Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548S Gene

Genomics for MIR548S Gene

Regulatory Elements for MIR548S Gene

Enhancers for MIR548S Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H011764 1 ENCODE dbSUPER 0.7 -2.9 -2865 0.1 PKNOX1 NFIB SAP130 ARID4B SIN3A MAX RAD21 CTBP1 GATA3 POLR2A LOC101929752 LPIN1 MIR548S GC02M011761
GH02H011778 1.4 Ensembl ENCODE dbSUPER 0.4 +11.5 11540 1.9 HDAC1 ELF3 RB1 ARID4B SIN3A DMAP1 RAD21 GLIS2 EGR1 ZNF143 LPIN1 ENSG00000230790 LOC101929752 LOC100506405 NTSR2 CDK8P1 MIR548S LOC105373430
GH02H011784 1.2 Ensembl ENCODE dbSUPER 0.4 +17.6 17552 0.7 HDGF CTCF KLF1 TRIM22 REST RAD21 MXD3 ZNF143 SMC3 ZBTB33 LPIN1 ENSG00000230790 LOC101929752 LOC100506405 MIR548S LOC105373430
GH02H011774 0.9 Ensembl ENCODE 0.4 +7.9 7943 1.7 HDGF ZNF687 MAX SIN3A ELF1 SCRT2 MLLT1 MYC LPIN1 ENSG00000230790 LOC100506405 LOC101929752 MIR548S LOC105373430
GH02H011828 1.4 Ensembl ENCODE 0.2 +62.8 62754 3.7 HDGF PKNOX1 FOXA2 ARNT ARID4B FEZF1 ZNF2 YY1 ZNF416 ZNF143 LPIN1 LOC105373430 MIR548S
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548S on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548S Gene

Genomic Locations for MIR548S Gene
82 bases
Plus strand

Genomic View for MIR548S Gene

Genes around MIR548S on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548S Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548S Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548S Gene

Proteins for MIR548S Gene

Post-translational modifications for MIR548S Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548S Gene

Domains & Families for MIR548S Gene

Gene Families for MIR548S Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548S: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548S Gene

Function for MIR548S Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548S Gene

Localization for MIR548S Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548S Gene

Pathways & Interactions for MIR548S Gene

SuperPathways for MIR548S Gene

No Data Available

Interacting Proteins for MIR548S Gene

Gene Ontology (GO) - Biological Process for MIR548S Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548S Gene

Drugs & Compounds for MIR548S Gene

No Compound Related Data Available

Transcripts for MIR548S Gene

mRNA/cDNA for MIR548S Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548S Gene

No ASD Table

Relevant External Links for MIR548S Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548S Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548S Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548S Gene:

genes like me logo Genes that share expression patterns with MIR548S: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548S Gene

Orthologs for MIR548S Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548S Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 100 (a)
Species where no ortholog for MIR548S was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548S Gene

Gene Tree for MIR548S (if available)
Gene Tree for MIR548S (if available)

Paralogs for MIR548S Gene

No data available for Paralogs for MIR548S Gene

Variants for MIR548S Gene

Sequence variations from dbSNP and Humsavar for MIR548S Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs137942440 Uncertain significance 11,765,613(+) AATCC(C/T)GCCAC upstream-variant-2KB, reference, synonymous-codon
rs149819112 Uncertain significance 11,765,660(+) GCCCA(A/G)TGGAA upstream-variant-2KB, reference, missense
rs192688285 Uncertain significance 11,765,679(+) TGCTC(C/G)CCTTT upstream-variant-2KB, reference, synonymous-codon
rs774490262 Uncertain significance 11,765,651(+) CATCC(A/G/T)CCAGC upstream-variant-2KB, reference, missense
rs886054796 Uncertain significance 11,765,665(+) ATGGA(A/G)ACCTC upstream-variant-2KB, reference, missense

Relevant External Links for MIR548S Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548S Gene

Disorders for MIR548S Gene

Relevant External Links for MIR548S

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548S Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548S Gene

Publications for MIR548S Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR548S Gene

Sources for MIR548S Gene

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