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Aliases for MIR548P Gene

Subcategory (RNA class) for MIR548P Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548P Gene

  • MicroRNA 548p 2 3 5
  • Hsa-Mir-548p 3
  • MIRN548P 3

External Ids for MIR548P Gene

Previous HGNC Symbols for MIR548P Gene

  • MIRN548P

Previous GeneCards Identifiers for MIR548P Gene

  • GC00U923044
  • GC05M100181

Summaries for MIR548P Gene

Entrez Gene Summary for MIR548P Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548P Gene

MIR548P (MicroRNA 548p) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548P Gene

Genomics for MIR548P Gene

Regulatory Elements for MIR548P Gene

Enhancers for MIR548P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G100840 1.7 FANTOM5 Ensembl ENCODE dbSUPER 12.2 -25.0 -24995 3.0 TBP JUN ZSCAN4 BACH1 ZIC2 RELA ARID3A GATA2 EED RELB MIR548P ST8SIA4 GC05M100870
GH05G100776 1.5 FANTOM5 Ensembl ENCODE 11.5 +39.0 39040 2.2 HDGF TBP ZNF133 BMI1 RFX5 GATA2 CBX5 FOS RELB ETV6 MIR548P ST8SIA4 RN7SKP62
GH05G100779 1.4 FANTOM5 Ensembl ENCODE 11.3 +36.3 36295 1.7 CTCF TBP PKNOX1 TBL1XR1 ASH2L CEBPG EBF1 RELA ARID3A POLR2A MIR548P ST8SIA4 RN7SKP62
GH05G100888 1 ENCODE dbSUPER 11.1 -73.5 -73488 3.6 TBP ZNF146 PKNOX1 BACH1 CEBPG ZBTB40 RELA ARID3A POLR2A CBX5 MIR548P ST8SIA4 GC05M100870
GH05G100837 0.9 ENCODE dbSUPER 12.2 -21.6 -21588 0.9 MTA2 NR2F1 JUNB TBX21 ARID3A GATA2 FOS MLLT1 SPI1 MIR548P ST8SIA4 GC05M100870
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548P on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548P Gene

Chromosome:
5
Start:
100,816,482 bp from pter
End:
100,816,565 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR548P Gene

Genes around MIR548P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548P Gene

ORGUL Member Location for MIR548P Gene

ORGUL Member Location for MIR548P gene

Proteins for MIR548P Gene

Post-translational modifications for MIR548P Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548P Gene

Domains & Families for MIR548P Gene

Gene Families for MIR548P Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548P: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548P Gene

Function for MIR548P Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548P Gene

Localization for MIR548P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548P Gene

Pathways & Interactions for MIR548P Gene

SuperPathways for MIR548P Gene

No Data Available

Interacting Proteins for MIR548P Gene

Gene Ontology (GO) - Biological Process for MIR548P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548P Gene

Drugs & Compounds for MIR548P Gene

No Compound Related Data Available

Transcripts for MIR548P Gene

mRNA/cDNA for MIR548P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548P Gene

No ASD Table

Relevant External Links for MIR548P Gene

GeneLoc Exon Structure for
MIR548P
ECgene alternative splicing isoforms for
MIR548P

Expression for MIR548P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548P Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548P Gene:

MIR548P
genes like me logo Genes that share expression patterns with MIR548P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548P Gene

Orthologs for MIR548P Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-548p 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR548P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548P Gene

ENSEMBL:
Gene Tree for MIR548P (if available)
TreeFam:
Gene Tree for MIR548P (if available)

Paralogs for MIR548P Gene

No data available for Paralogs for MIR548P Gene

Variants for MIR548P Gene

Sequence variations from dbSNP and Humsavar for MIR548P Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000114274 -- 100,817,527(+) ACATA(C/T)TGAAA intron-variant, upstream-variant-2KB
rs1002456439 -- 100,817,573(+) TAGTC(C/T)TTTCA intron-variant, upstream-variant-2KB
rs1003237271 -- 100,816,230(+) CAAAG(A/G)AAAGA intron-variant, downstream-variant-500B
rs1003392330 -- 100,816,138(+) TCTCC(A/G)TGAAA intron-variant, downstream-variant-500B
rs1006477636 -- 100,818,540(+) TTTCC(A/G)TGCAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548P Gene

Variant ID Type Subtype PubMed ID
esv3890678 CNV gain 25118596
nsv1021183 CNV gain 25217958
nsv1023765 CNV loss 25217958

Relevant External Links for MIR548P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548P Gene

Disorders for MIR548P Gene

Relevant External Links for MIR548P

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548P

No disorders were found for MIR548P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548P Gene

Publications for MIR548P Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548P Gene

Sources for MIR548P Gene

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