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Aliases for MIR548O Gene

Subcategory (RNA class) for MIR548O Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548O Gene

  • MicroRNA 548o 2 3 5
  • Hsa-Mir-548o 3
  • MIRN548O 3

External Ids for MIR548O Gene

Previous HGNC Symbols for MIR548O Gene

  • MIRN548O

Previous GeneCards Identifiers for MIR548O Gene

  • GC00U923117
  • GC07M101834
  • GC07M102046

Summaries for MIR548O Gene

Entrez Gene Summary for MIR548O Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548O Gene

MIR548O (MicroRNA 548o) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548O Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548O Gene

Genomics for MIR548O Gene

Regulatory Elements for MIR548O Gene

Enhancers for MIR548O Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H102439 1.5 Ensembl ENCODE dbSUPER 12.6 -35.9 -35880 4 HDGF PKNOX1 ARNT TCF12 ZNF766 GATA2 ELK1 ZNF143 FOS ATF7 PRKRIP1 ENSG00000272949 MIR548O POLR2J ENSG00000239480 PIR32382
GH07H102444 1.1 ENCODE dbSUPER 12.6 -39.4 -39351 1 HDGF PKNOX1 RB1 ZNF366 ATF7 RUNX3 CREM IKZF2 ZEB2 ZNF592 ORAI2 ENSG00000272949 POLR2J MIR548O PRKRIP1 UPK3BL1 ENSG00000239480 PIR32382
GH07H102470 0.6 ENCODE 13.1 -64.8 -64774 0 HNF4G MAX HNF4A PRDM10 ZNF623 GABPA YY1 MIR548O PRKRIP1 MIR4467 MIR5090
GH07H102381 0.4 ENCODE 12.6 +24.2 24172 0 JUND POLR2A MIR548O SH2B2 ENSG00000239486 ENSG00000239969
GH07H102380 0.2 ENCODE 12.6 +24.8 24787 0 MIR548O SH2B2 ENSG00000239486 ENSG00000239969
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548O on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548O Gene

Chromosome:
7
Start:
102,405,742 bp from pter
End:
102,405,855 bp from pter
Size:
114 bases
Orientation:
Minus strand

Genomic View for MIR548O Gene

Genes around MIR548O on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548O Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548O Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548O Gene

ORGUL Member Location for MIR548O Gene

ORGUL Member Location for MIR548O gene

Proteins for MIR548O Gene

Post-translational modifications for MIR548O Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548O Gene

Domains & Families for MIR548O Gene

Gene Families for MIR548O Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548O: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548O Gene

Function for MIR548O Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR548O
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548O Gene

Localization for MIR548O Gene

Gene Ontology (GO) - Cellular Components for MIR548O Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR548O: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR548O Gene

Pathways & Interactions for MIR548O Gene

SuperPathways for MIR548O Gene

No Data Available

Interacting Proteins for MIR548O Gene

Gene Ontology (GO) - Biological Process for MIR548O Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548O Gene

Drugs & Compounds for MIR548O Gene

No Compound Related Data Available

Transcripts for MIR548O Gene

mRNA/cDNA for MIR548O Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR548O
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548O Gene

No ASD Table

Relevant External Links for MIR548O Gene

GeneLoc Exon Structure for
MIR548O
ECgene alternative splicing isoforms for
MIR548O

Expression for MIR548O Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548O Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548O Gene:

MIR548O
genes like me logo Genes that share expression patterns with MIR548O: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548O Gene

Orthologs for MIR548O Gene

Evolution for MIR548O Gene

ENSEMBL:
Gene Tree for MIR548O (if available)
TreeFam:
Gene Tree for MIR548O (if available)

No data available for Orthologs for MIR548O Gene

Paralogs for MIR548O Gene

No data available for Paralogs for MIR548O Gene

Variants for MIR548O Gene

Sequence variations from dbSNP and Humsavar for MIR548O Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1006558018 -- 102,406,347(+) GTTGT(C/T)GCAGG intron-variant, upstream-variant-2KB
rs1009311181 -- 102,407,769(+) GGTTA(C/T)TGACA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1011743390 -- 102,406,056(+) AATTT(A/G)TTCAA intron-variant, upstream-variant-2KB
rs1012635858 -- 102,407,647(+) ACCCA(C/T)TGAAT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1017566617 -- 102,407,778(+) CATCT(A/C)CCCCT intron-variant, nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548O Gene

Variant ID Type Subtype PubMed ID
dgv6538n100 CNV gain 25217958
esv2759548 CNV gain 17122850
nsv428182 CNV gain 18775914
nsv464664 CNV gain 19166990
nsv464665 CNV loss 19166990
nsv607998 CNV gain+loss 21841781
nsv831083 CNV loss 17160897

Relevant External Links for MIR548O Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548O

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548O Gene

Disorders for MIR548O Gene

Relevant External Links for MIR548O

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548O

No disorders were found for MIR548O Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548O Gene

Publications for MIR548O Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR548O Gene

Sources for MIR548O Gene

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