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Aliases for MIR548N Gene

Subcategory (RNA class) for MIR548N Gene


Quality Score for this RNA gene is


Aliases for MIR548N Gene

  • MicroRNA 548n 2 3 5
  • Hsa-Mir-548n 3
  • MIRN548N 3

External Ids for MIR548N Gene

Previous HGNC Symbols for MIR548N Gene

  • MIRN548N

Previous GeneCards Identifiers for MIR548N Gene

  • GC00U923003
  • GC09P017593

Summaries for MIR548N Gene

Entrez Gene Summary for MIR548N Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548N Gene

MIR548N (MicroRNA 548n) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548N Gene

Genomics for MIR548N Gene

Regulatory Elements for MIR548N Gene

Enhancers for MIR548N Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F035002 1.2 Ensembl ENCODE 0.2 -63.4 -63425 3.4 PKNOX1 INSM2 KLF17 SIN3A FEZF1 ZNF366 ZNF416 SMARCC2 FOS SMARCC1 DPY19L1 LOC105375228 MIR548N
GH07F034990 1.1 Ensembl ENCODE 0.2 -51.0 -50969 2.3 SOX13 JUN MAX ZBTB40 KMT2B ZNF7 RARA CBX5 ELK1 ZNF143 DPY19L1 LOC105375228 MIR548N
GH07F034996 0.9 Ensembl 0.2 -56.0 -55956 0.8 HDAC1 HDGF ATF1 SIN3A RAD21 ZNF48 YY1 ZNF335 SCRT2 RCOR1 LOC105375228 MIR548N
GH07F035024 0.8 ENCODE 0.2 -85.1 -85107 3.0 SIX4 ZFP64 SIN3A CEBPG ZNF316 ZFHX2 GATA3 CTBP1 EED ETV6 DPY19L1 LOC105375228 MIR548N
GH07F035014 0.8 ENCODE 0.2 -74.7 -74732 1.5 CTCF HDAC1 ATF1 DDX20 ETV1 TEAD4 ZNF175 GATA3 FOXK2 RFX1 DPY19L1 LOC105375228 MIR548N
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548N on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548N Gene

34,940,760 bp from pter
34,940,834 bp from pter
75 bases
Minus strand

Genomic View for MIR548N Gene

Genes around MIR548N on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548N Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548N Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548N Gene

Proteins for MIR548N Gene

Post-translational modifications for MIR548N Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548N Gene

Domains & Families for MIR548N Gene

Gene Families for MIR548N Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548N: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548N Gene

Function for MIR548N Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548N Gene

Localization for MIR548N Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548N Gene

Pathways & Interactions for MIR548N Gene

SuperPathways for MIR548N Gene

No Data Available

Interacting Proteins for MIR548N Gene

Gene Ontology (GO) - Biological Process for MIR548N Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548N Gene

Transcripts for MIR548N Gene

mRNA/cDNA for MIR548N Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548N Gene

No ASD Table

Relevant External Links for MIR548N Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548N Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548N Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548N Gene

Orthologs for MIR548N Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548N Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-548n 35
  • 93 (a)
Species where no ortholog for MIR548N was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548N Gene

Gene Tree for MIR548N (if available)
Gene Tree for MIR548N (if available)

Paralogs for MIR548N Gene

No data available for Paralogs for MIR548N Gene

Variants for MIR548N Gene

Sequence variations from dbSNP and Humsavar for MIR548N Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10250525 -- 34,942,299(+) GGCCT(C/T)AAGCA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1063284 -- 34,940,351(-) TTACC(A/G)ATGTA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1063285 -- 34,940,283(-) ATTGT(G/T)TTTGC intron-variant, downstream-variant-500B, upstream-variant-2KB, reference, synonymous-codon
rs112629156 -- 34,941,682(+) AAAAG(A/C)CTTTG intron-variant, upstream-variant-2KB
rs116166513 -- 34,941,359(+) CACAA(A/G)TTGCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548N Gene

Variant ID Type Subtype PubMed ID
nsv998891 CNV loss 25217958
nsv966775 CNV duplication 23825009
nsv946093 CNV duplication 23825009
nsv830952 CNV gain 17160897
nsv830793 CNV loss 17160897
nsv823642 CNV loss 20364138
nsv526047 CNV gain 19592680
nsv509391 CNV insertion 20534489
nsv474541 CNV novel sequence insertion 20440878
nsv436907 CNV insertion 17901297
nsv2110 CNV deletion 18451855
nsv2099 CNV insertion 18451855
nsv1002853 CNV gain 25217958
esv3612750 OTHER inversion 21293372
esv3586926 CNV loss 21293372
esv3578021 CNV loss 25503493
esv2715263 CNV deletion 23290073
esv2491678 CNV deletion 19546169
dgv6320n100 CNV gain 25217958
dgv1080e201 CNV deletion 23290073

Relevant External Links for MIR548N Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548N Gene

Disorders for MIR548N Gene

Relevant External Links for MIR548N

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548N Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548N Gene

Publications for MIR548N Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548N Gene

Sources for MIR548N Gene

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