Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR548M Gene

Subcategory (RNA class) for MIR548M Gene


Quality Score for this RNA gene is


Aliases for MIR548M Gene

  • MicroRNA 548m 2 3 5
  • Hsa-Mir-548m 3
  • MIRN548M 3

External Ids for MIR548M Gene

Previous HGNC Symbols for MIR548M Gene

  • MIRN548M

Previous GeneCards Identifiers for MIR548M Gene

  • GC00U923009
  • GC0XM094205
  • GC0XM094318

Summaries for MIR548M Gene

Entrez Gene Summary for MIR548M Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548M Gene

MIR548M (MicroRNA 548m) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548M Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548M Gene

Genomics for MIR548M Gene

Regulatory Elements for MIR548M Gene

Enhancers for MIR548M Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH095083 0.2 ENCODE 13 -21.2 -21151 1 MIR548M GC0XM095243
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548M on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548M Gene

95,063,141 bp from pter
95,063,226 bp from pter
86 bases
Minus strand

Genomic View for MIR548M Gene

Genes around MIR548M on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548M Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548M Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548M Gene

Proteins for MIR548M Gene

Post-translational modifications for MIR548M Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548M Gene

Domains & Families for MIR548M Gene

Gene Families for MIR548M Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548M: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548M Gene

Function for MIR548M Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR548M
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548M Gene

Localization for MIR548M Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548M Gene

Pathways & Interactions for MIR548M Gene

SuperPathways for MIR548M Gene

No Data Available

Interacting Proteins for MIR548M Gene

Gene Ontology (GO) - Biological Process for MIR548M Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548M Gene

Drugs & Compounds for MIR548M Gene

No Compound Related Data Available

Transcripts for MIR548M Gene

mRNA/cDNA for MIR548M Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR548M
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548M Gene

No ASD Table

Relevant External Links for MIR548M Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548M Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548M Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548M Gene

Orthologs for MIR548M Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548M Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 80 (a)
Species where no ortholog for MIR548M was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548M Gene

Gene Tree for MIR548M (if available)
Gene Tree for MIR548M (if available)

Paralogs for MIR548M Gene

No data available for Paralogs for MIR548M Gene

Variants for MIR548M Gene

Sequence variations from dbSNP and Humsavar for MIR548M Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000053868 -- 95,064,095(+) TGAAA(A/G)CTTTC upstream-variant-2KB
rs1002510150 -- 95,063,114(+) AGATA(C/T)TTGCC downstream-variant-500B
rs1008247746 -- 95,063,614(+) TAACC(A/G)AGAAG upstream-variant-2KB
rs1008301636 -- 95,063,988(+) GAGAC(A/G)CAGTT upstream-variant-2KB
rs1010550513 -- 95,065,146(+) TCAAT(A/G)AAATT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548M Gene

Variant ID Type Subtype PubMed ID
dgv2345e212 CNV loss 25503493
esv3574235 CNV loss 25503493
esv3576979 CNV gain 25503493
nsv524998 CNV gain 19592680

Relevant External Links for MIR548M Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548M Gene

Disorders for MIR548M Gene

Relevant External Links for MIR548M

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548M Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548M Gene

Publications for MIR548M Gene

  1. A microenvironment-mediated c-Myc/miR-548m/HDAC6 amplification loop in non-Hodgkin B cell lymphomas. (PMID: 24216476) Lwin T … Tao J (The Journal of clinical investigation 2013) 3 60
  2. miR-1279, miR-548j, miR-548m, and miR-548d-5p binding sites in CDSs of paralogous and orthologous PTPN12, MSH6, and ZEB1 Genes. (PMID: 23957009) Ivashchenko AT … Berillo OA (BioMed research international 2013) 3 60
  3. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR548M Gene

Sources for MIR548M Gene

Loading form....