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MIR548L Gene(RNA Gene)

MicroRNA 548l

GCID:
GC11M094466
GIFtS:
15
Genes Participants
UDN Logo

Aliases for MIR548L Gene

Subcategory (RNA class) for MIR548L Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548L Gene

  • MicroRNA 548l 2 3 5
  • Hsa-Mir-548l 3
  • MIRN548L 3

External Ids for MIR548L Gene

ORGUL Members for MIR548L Gene

Previous HGNC Symbols for MIR548L Gene

  • MIRN548L

Previous GeneCards Identifiers for MIR548L Gene

  • GC00U922821
  • GC11M093840
  • GC11M094199

Summaries for MIR548L Gene

Entrez Gene Summary for MIR548L Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548L Gene

MIR548L (MicroRNA 548l) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548L Gene

Genomics for MIR548L Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR548L Gene

Enhancers for MIR548L Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR548L on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548L Gene

Chromosome:
11
Start:
94,466,495 bp from pter
End:
94,466,580 bp from pter
Size:
86 bases
Orientation:
Minus strand

Genomic View for MIR548L Gene

Genes around MIR548L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548L Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR548L Gene

Proteins for MIR548L Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR548L Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548L Gene

Domains & Families for MIR548L Gene

Gene Families for MIR548L Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548L: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548L Gene

Function for MIR548L Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548L Gene

Localization for MIR548L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548L Gene

Pathways & Interactions for MIR548L Gene

SuperPathways for MIR548L Gene

PathCards logoMore details on SuperPathways for MIR548L
No Data Available

Interacting Proteins for MIR548L Gene

Gene Ontology (GO) - Biological Process for MIR548L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548L Gene

Drugs & Compounds for MIR548L Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR548L Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR548L Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548L Gene

No ASD Table

Relevant External Links for MIR548L Gene

GeneLoc Exon Structure for
MIR548L
ECgene alternative splicing isoforms for
MIR548L

Expression for MIR548L Gene

Products:

  1. Primer

mRNA expression in normal human tissues for MIR548L Gene

mRNA expression in normal human tissues for MIR548L Gene
mRNA expression by GTEx for MIR548L Gene
genes like me logo Genes that share expression patterns with MIR548L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR548L Gene

Orthologs for MIR548L Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ptr-mir-548l 36
  • 99 (a)
 OneToOne
Species with no ortholog for MIR548L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548L Gene

ENSEMBL:
Gene Tree for MIR548L (if available)
TreeFam:
Gene Tree for MIR548L (if available)

Paralogs for MIR548L Gene

No data available for Paralogs for MIR548L Gene

Variants for MIR548L Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MIR548L Gene

Disorders for MIR548L Gene

Relevant External Links for MIR548L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548L

No disorders were found for MIR548L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548L Gene

Publications for MIR548L Gene

  1. microRNA-548l is involved in the migration and invasion of non-small cell lung cancer by targeting the AKT1 signaling pathway. (PMID: 25245053) Liu C. … Zhou R. (J. Cancer Res. Clin. Oncol. 2015) 3 67
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR548L Gene

Sources for MIR548L Gene

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