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Aliases for MIR548K Gene

Subcategory (RNA class) for MIR548K Gene


Quality Score for this RNA gene is


Aliases for MIR548K Gene

  • MicroRNA 548k 2 3 5
  • Hsa-Mir-548k 3
  • MIRN548K 3

External Ids for MIR548K Gene

Previous HGNC Symbols for MIR548K Gene

  • MIRN548K

Previous GeneCards Identifiers for MIR548K Gene

  • GC00U923047
  • GC11P069808
  • GC11P070130

Summaries for MIR548K Gene

Entrez Gene Summary for MIR548K Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548K Gene

MIR548K (MicroRNA 548k) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548K Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548K Gene

Genomics for MIR548K Gene

GeneHancer (GH) Regulatory Elements for MIR548K Gene

Promoters and enhancers for MIR548K Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I070281 Enhancer 0.4 ENCODE 0.8 -2.4 -2424 0.8 CTCF ZNF449 PPFIA1 H2AFZP4 MIR548K
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR548K on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548K Gene

Genomic Locations for MIR548K Gene
116 bases
Plus strand

Genomic View for MIR548K Gene

Genes around MIR548K on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548K Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548K Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548K Gene

Proteins for MIR548K Gene

Post-translational modifications for MIR548K Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548K Gene

Domains & Families for MIR548K Gene

Gene Families for MIR548K Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548K: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548K Gene

Function for MIR548K Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548K Gene

Localization for MIR548K Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548K Gene

Pathways & Interactions for MIR548K Gene

SuperPathways for MIR548K Gene

No Data Available

Interacting Proteins for MIR548K Gene

Gene Ontology (GO) - Biological Process for MIR548K Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548K Gene

Drugs & Compounds for MIR548K Gene

No Compound Related Data Available

Transcripts for MIR548K Gene

mRNA/cDNA for MIR548K Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548K Gene

No ASD Table

Relevant External Links for MIR548K Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548K Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548K Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548K Gene:

genes like me logo Genes that share expression patterns with MIR548K: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548K Gene

Orthologs for MIR548K Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548K Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-548k 34
  • 100 (a)
Species where no ortholog for MIR548K was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548K Gene

Gene Tree for MIR548K (if available)
Gene Tree for MIR548K (if available)

Paralogs for MIR548K Gene

No data available for Paralogs for MIR548K Gene

Variants for MIR548K Gene

Sequence variations from dbSNP and Humsavar for MIR548K Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000222430 -- 70,284,411(+) T/C downstream_transcript_variant
rs1001226928 -- 70,282,275(+) A/G upstream_transcript_variant
rs1002971770 -- 70,283,584(+) C/T upstream_transcript_variant
rs1004575181 -- 70,283,429(+) G/T upstream_transcript_variant
rs1004738558 -- 70,282,641(+) G/C upstream_transcript_variant

Additional Variant Information for MIR548K Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548K Gene

Disorders for MIR548K Gene

Additional Disease Information for MIR548K

No disorders were found for MIR548K Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548K Gene

Publications for MIR548K Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin RD … Marra MA (Genome research 2008) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR548K Gene

Sources for MIR548K Gene

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