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Aliases for MIR548J Gene

Subcategory (RNA class) for MIR548J Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548J Gene

  • MicroRNA 548j 2 3
  • Hsa-Mir-548j 3
  • MIRN548J 3

External Ids for MIR548J Gene

Previous Symbols for MIR548J Gene

  • MIRN548J

Summaries for MIR548J Gene

Entrez Gene Summary for MIR548J Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Nov 2009]

GeneCards Summary for MIR548J Gene

MIR548J (MicroRNA 548j) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548J Gene

Genomics for MIR548J Gene

Genomic Location for MIR548J Gene

Start:
26,555,212 bp from pter
End:
26,555,323 bp from pter
Size:
112 bases
Orientation:
Minus strand

Genomic View for MIR548J Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548J Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548J Gene

ORGUL Member Location for MIR548J Gene

ORGUL Member Location for MIR548J gene

No data available for Regulatory Elements for MIR548J Gene

Proteins for MIR548J Gene

Post-translational modifications for MIR548J Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548J Gene

Domains for MIR548J Gene

Gene Families for MIR548J Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR548J: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR548J Gene

Function for MIR548J Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548J Gene

Localization for MIR548J Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR548J Gene

Pathways for MIR548J Gene

SuperPathways for MIR548J Gene

No Data Available

Interacting Proteins for MIR548J Gene

Gene Ontology (GO) - Biological Process for MIR548J Gene

None

No data available for Pathways by source for MIR548J Gene

Transcripts for MIR548J Gene

mRNA/cDNA for MIR548J Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548J Gene

No ASD Table

Relevant External Links for MIR548J Gene

GeneLoc Exon Structure for
MIR548J
ECgene alternative splicing isoforms for
MIR548J

Expression for MIR548J Gene

mRNA expression in normal human tissues for MIR548J Gene

genes like me logo Genes that share expressions with MIR548J: view

Orthologs for MIR548J Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548J Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-548j 37
  • 98 (a)
OneToOne
Species with no ortholog for MIR548J:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548J Gene

ENSEMBL:
Gene Tree for MIR548J (if available)
TreeFam:
Gene Tree for MIR548J (if available)

Paralogs for MIR548J Gene

No data available for Paralogs for MIR548J Gene

Variants for MIR548J Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548J Gene

Variant ID Type Subtype PubMed ID
nsv7350 OTHER Inversion 18451855
dgv1397e1 CNV Complex 17122850

Relevant External Links for MIR548J Gene

HapMap Linkage Disequilibrium report
MIR548J

No data available for Sequence variations from dbSNP and Humsavar for MIR548J Gene

Disorders for MIR548J Gene

No disorders were found for MIR548J Gene.

No data available for UniProtKB/Swiss-Prot for MIR548J Gene

Publications for MIR548J Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3
  3. miR-1279, miR-548j, miR-548m, and miR-548d-5p binding sites in CDSs of paralogous and orthologous PTPN12, MSH6, and ZEB1 Genes. (PMID: 23957009) Ivashchenko A.T. … Berillo O.A. (Biomed Res Int 2013) 3

Products for MIR548J Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR548J
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR548J
    • Block miRNA regulation of MIR548J using miScript Target Protectors

    Sources for MIR548J Gene

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