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MIR548I4 Gene(RNA Gene)

MicroRNA 548i-4

GCID:
GC0XM084225
GIFtS:
14
Genes Participants
UDN Logo

Aliases for MIR548I4 Gene

Subcategory (RNA class) for MIR548I4 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548I4 Gene

  • MicroRNA 548i-4 2 3 5
  • Hsa-Mir-548i-4 3
  • MIR548I-4 3
  • MIRN548I4 3

External Ids for MIR548I4 Gene

ORGUL Members for MIR548I4 Gene

Previous HGNC Symbols for MIR548I4 Gene

  • MIRN548I4

Previous GeneCards Identifiers for MIR548I4 Gene

  • GC00U922982
  • GC0XM083368
  • GC0XM083480

Summaries for MIR548I4 Gene

Entrez Gene Summary for MIR548I4 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548I4 Gene

MIR548I4 (MicroRNA 548i-4) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548I4 Gene

Genomics for MIR548I4 Gene

Products:

  1. Regulatory Element

Regulatory Elements for MIR548I4 Gene

Enhancers for MIR548I4 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR548I4 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548I4 Gene

Chromosome:
X
Start:
84,225,752 bp from pter
End:
84,225,828 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR548I4 Gene

Genes around MIR548I4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548I4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548I4 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR548I4 Gene

Proteins for MIR548I4 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR548I4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548I4 Gene

Domains & Families for MIR548I4 Gene

Gene Families for MIR548I4 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548I4: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548I4 Gene

Function for MIR548I4 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548I4 Gene

Localization for MIR548I4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548I4 Gene

Pathways & Interactions for MIR548I4 Gene

SuperPathways for MIR548I4 Gene

PathCards logoMore details on SuperPathways for MIR548I4
No Data Available

Interacting Proteins for MIR548I4 Gene

Gene Ontology (GO) - Biological Process for MIR548I4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548I4 Gene

Drugs & Compounds for MIR548I4 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR548I4 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MIR548I4 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548I4 Gene

No ASD Table

Relevant External Links for MIR548I4 Gene

GeneLoc Exon Structure for
MIR548I4
ECgene alternative splicing isoforms for
MIR548I4

Expression for MIR548I4 Gene

Products:

  1. Primer
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR548I4 Gene

Orthologs for MIR548I4 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548I4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia -- 36
  • 75 (a)
 ManyToMany
Species with no ortholog for MIR548I4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548I4 Gene

ENSEMBL:
Gene Tree for MIR548I4 (if available)
TreeFam:
Gene Tree for MIR548I4 (if available)

Paralogs for MIR548I4 Gene

No data available for Paralogs for MIR548I4 Gene

Variants for MIR548I4 Gene

Sequence variations from dbSNP and Humsavar for MIR548I4 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs748502776 -- 84,227,655(+) TAGAG(G/T)TTTAC upstream-variant-2KB
rs749182163 -- 84,225,785(+) TTTGC(C/T)GTTAA nc-transcript-variant
rs750204154 -- 84,227,651(+) GTGAT(A/G)GAGGT upstream-variant-2KB
rs2334021 -- 84,226,375(-) GGGGG(G/T)ATTCT upstream-variant-2KB
rs750571950 -- 84,227,206(+) TTTTA(C/T)TGTTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548I4 Gene

Variant ID Type Subtype PubMed ID
nsv889396 CNV Gain 21882294
esv999216 CNV Gain 20482838
nsv526693 CNV Gain 19592680
dgv177e180 CNV Loss 20482838
dgv1246e199 CNV Deletion 23128226
esv26187 CNV Loss 19812545
dgv1142n67 CNV Loss 20364138
esv1003793 CNV Gain 20482838
esv2735307 CNV Deletion 23290073
esv2735308 CNV Deletion 23290073
nsv5997 CNV Insertion 18451855
esv270321 CNV Insertion 20981092
esv273229 CNV Insertion 20981092
esv2735309 CNV Deletion 23290073
nsv517892 CNV Gain 19592680
esv22733 CNV Loss 19812545
esv22430 CNV Loss 19812545
nsv824372 CNV Loss 20364138
esv272196 CNV Insertion 20981092
esv270385 CNV Insertion 20981092

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR548I4 Gene

Disorders for MIR548I4 Gene

Relevant External Links for MIR548I4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548I4

No disorders were found for MIR548I4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548I4 Gene

Publications for MIR548I4 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR548I4 Gene

Sources for MIR548I4 Gene

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