Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR548I2 Gene

Subcategory (RNA class) for MIR548I2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548I2 Gene

  • MicroRNA 548i-2 2 3 5
  • Hsa-Mir-548i-2 3
  • Mir-548i-2 3
  • MIR548I-2 3
  • MIRN548I2 3

External Ids for MIR548I2 Gene

Previous HGNC Symbols for MIR548I2 Gene

  • MIRN548I2

Previous GeneCards Identifiers for MIR548I2 Gene

  • GC00U922922
  • GC04M009167

Summaries for MIR548I2 Gene

Entrez Gene Summary for MIR548I2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548I2 Gene

MIR548I2 (MicroRNA 548i-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548I2 Gene

Genomics for MIR548I2 Gene

Genomic Location for MIR548I2 Gene

Chromosome:
4
Start:
9,556,168 bp from pter
End:
9,556,316 bp from pter
Size:
149 bases
Orientation:
Minus strand

Genomic View for MIR548I2 Gene

Genes around MIR548I2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548I2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548I2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548I2 Gene

No data available for Regulatory Elements for MIR548I2 Gene

Proteins for MIR548I2 Gene

Post-translational modifications for MIR548I2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548I2 Gene

Domains & Families for MIR548I2 Gene

Gene Families for MIR548I2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548I2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548I2 Gene

Function for MIR548I2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548I2 Gene

Localization for MIR548I2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548I2 Gene

Pathways & Interactions for MIR548I2 Gene

SuperPathways for MIR548I2 Gene

No Data Available

Interacting Proteins for MIR548I2 Gene

Gene Ontology (GO) - Biological Process for MIR548I2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548I2 Gene

Transcripts for MIR548I2 Gene

mRNA/cDNA for MIR548I2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548I2 Gene

No ASD Table

Relevant External Links for MIR548I2 Gene

GeneLoc Exon Structure for
MIR548I2
ECgene alternative splicing isoforms for
MIR548I2

Expression for MIR548I2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR548I2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548I2 Gene:

MIR548I2
genes like me logo Genes that share expression patterns with MIR548I2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548I2 Gene

Orthologs for MIR548I2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548I2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 97 (a)
OneToOne
Species where no ortholog for MIR548I2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548I2 Gene

ENSEMBL:
Gene Tree for MIR548I2 (if available)
TreeFam:
Gene Tree for MIR548I2 (if available)

Paralogs for MIR548I2 Gene

No data available for Paralogs for MIR548I2 Gene

Variants for MIR548I2 Gene

Sequence variations from dbSNP and Humsavar for MIR548I2 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs10006409 -- 9,557,972(+) TGTGT(C/T)GTGTT upstream-variant-2KB
rs10006755 -- 9,556,021(+) AGGGC(A/G)ACAGT downstream-variant-500B
rs10010393 -- 9,556,916(+) AGTTG(C/T)GAGGC upstream-variant-2KB
rs10010844 -- 9,557,989(+) TGTGT(A/G)TGTGT upstream-variant-2KB
rs10013288 -- 9,557,597(+) ATCCA(A/T)TTCTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548I2 Gene

Variant ID Type Subtype PubMed ID
nsv999615 CNV gain 25217958
nsv980183 CNV duplication 23825009
nsv818213 CNV gain 17921354
nsv593661 CNV loss 21841781
nsv525830 CNV loss 19592680
nsv520290 CNV loss 19592680
nsv508273 CNV deletion 20534489
nsv471623 CNV gain+loss 15918152
nsv433363 CNV gain 18776910
nsv428437 CNV gain 18775914
nsv1014335 CNV gain 25217958
nsv1012965 CNV loss 25217958
nsv1005698 CNV gain 25217958
nsv1002765 CNV loss 25217958
esv3893871 CNV gain 25118596
esv3599581 CNV gain 21293372
esv34196 OTHER inversion 12058347
esv28874 CNV gain+loss 19812545
esv2763860 CNV gain+loss 21179565
esv2759222 CNV gain+loss 17122850
esv2678198 CNV deletion 23128226
dgv8960n54 CNV gain 21841781
dgv645n27 CNV gain 19166990
dgv5n29 CNV loss 16826518
dgv5116n100 CNV gain 25217958
dgv5115n100 CNV loss 25217958
dgv5114n100 CNV loss 25217958
dgv5113n100 CNV gain 25217958
dgv5108n100 CNV gain 25217958
dgv5104n100 CNV gain 25217958
dgv5103n100 CNV gain 25217958
dgv5102n100 CNV gain 25217958

Relevant External Links for MIR548I2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548I2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548I2 Gene

Disorders for MIR548I2 Gene

Relevant External Links for MIR548I2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548I2

No disorders were found for MIR548I2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548I2 Gene

Publications for MIR548I2 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548I2 Gene

Sources for MIR548I2 Gene

Content
Loading form....