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Aliases for MIR548H4 Gene

Subcategory (RNA class) for MIR548H4 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548H4 Gene

  • MicroRNA 548h-4 2 3
  • Hsa-Mir-548h-4 3
  • MIR548H-4 3
  • MIRN548H4 3

External Ids for MIR548H4 Gene

Previous HGNC Symbols for MIR548H4 Gene

  • MIRN548H4

Previous GeneCards Identifiers for MIR548H4 Gene

  • GC00U922999
  • GC08M026963
  • GC08M026906

Summaries for MIR548H4 Gene

Entrez Gene Summary for MIR548H4 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Nov 2009]

GeneCards Summary for MIR548H4 Gene

MIR548H4 (MicroRNA 548h-4) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548H4 Gene

Genomics for MIR548H4 Gene

Genomic Location for MIR548H4 Gene

Start:
27,048,853 bp from pter
End:
27,048,963 bp from pter
Size:
111 bases
Orientation:
Minus strand

Genomic View for MIR548H4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548H4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548H4 Gene

ORGUL Member Location for MIR548H4 Gene

ORGUL Member Location for MIR548H4 gene

No data available for Regulatory Elements for MIR548H4 Gene

Proteins for MIR548H4 Gene

Post-translational modifications for MIR548H4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548H4 Gene

Domains for MIR548H4 Gene

Gene Families for MIR548H4 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548H4: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548H4 Gene

Function for MIR548H4 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548H4 Gene

Localization for MIR548H4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548H4 Gene

Pathways for MIR548H4 Gene

SuperPathways for MIR548H4 Gene

No Data Available

Interacting Proteins for MIR548H4 Gene

Gene Ontology (GO) - Biological Process for MIR548H4 Gene

None

No data available for Pathways by source for MIR548H4 Gene

Transcripts for MIR548H4 Gene

mRNA/cDNA for MIR548H4 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548H4 Gene

No ASD Table

Relevant External Links for MIR548H4 Gene

GeneLoc Exon Structure for
MIR548H4
ECgene alternative splicing isoforms for
MIR548H4

Expression for MIR548H4 Gene

mRNA expression in normal human tissues for MIR548H4 Gene

genes like me logo Genes that share expressions with MIR548H4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR548H4 Gene

Orthologs for MIR548H4 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548H4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 68 (a)
ManyToMany
Species with no ortholog for MIR548H4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548H4 Gene

ENSEMBL:
Gene Tree for MIR548H4 (if available)
TreeFam:
Gene Tree for MIR548H4 (if available)

Paralogs for MIR548H4 Gene

No data available for Paralogs for MIR548H4 Gene

Variants for MIR548H4 Gene

Sequence variations from dbSNP and Humsavar for MIR548H4 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs6981379 -- 27,048,437(+) tttga(A/G)accag downstream-variant-500B
rs7006694 -- 27,048,763(+) TTTCC(C/T)TTTTC downstream-variant-500B
rs7818211 -- 27,049,556(+) TCACC(A/G)TTTTA upstream-variant-2KB
rs7818664 -- 27,049,814(+) GAAAA(C/G)AAATA upstream-variant-2KB
rs7823902 -- 27,050,420(+) TTTAC(C/T)GCAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548H4 Gene

Variant ID Type Subtype PubMed ID
nsv833046 CNV Loss 17160897
nsv507786 CNV Insertion 20534489
esv9665 CNV Gain 19470904
nsv1584 CNV Loss 18451855
esv33141 CNV Gain 17666407
esv33333 CNV Gain 17666407
esv33369 CNV Gain 17666407
esv2669530 CNV Deletion 23128226
nsv521203 CNV Loss 19592680
esv275002 CNV Gain+Loss 21479260
esv2677144 CNV Deletion 23128226
nsv517185 CNV Gain+Loss 19592680
nsv904328 CNV Loss 21882294

Relevant External Links for MIR548H4 Gene

HapMap Linkage Disequilibrium report
MIR548H4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR548H4 Gene

Disorders for MIR548H4 Gene

No disorders were found for MIR548H4 Gene.

No data available for UniProtKB/Swiss-Prot for MIR548H4 Gene

Publications for MIR548H4 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3

Products for MIR548H4 Gene

Sources for MIR548H4 Gene

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