Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR548H3 Gene

Subcategory (RNA class) for MIR548H3 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548H3 Gene

  • MicroRNA 548h-3 2 3 5
  • Hsa-Mir-548h-3 3
  • MIR548H-3 3
  • MIRN548H3 3

External Ids for MIR548H3 Gene

Previous HGNC Symbols for MIR548H3 Gene

  • MIRN548H3

Previous GeneCards Identifiers for MIR548H3 Gene

  • GC00U922909
  • GC17M013388

Summaries for MIR548H3 Gene

Entrez Gene Summary for MIR548H3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548H3 Gene

MIR548H3 (MicroRNA 548h-3) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548H3 Gene

Genomics for MIR548H3 Gene

Regulatory Elements for MIR548H3 Gene

Enhancers for MIR548H3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G013508 1.3 FANTOM5 ENCODE 11.6 +34.0 34007 2.7 PKNOX1 ATF1 CREB3L1 ARNT TCF12 ZNF766 ELK1 GATA2 NCOA1 REST MIR548H3 GC17P013426
GH17G013513 1 ENCODE 11.6 +30.5 30468 0.2 ATF1 PKNOX1 SIN3A ARID4B ZNF48 YY1 GLIS2 GATA2 ZNF263 MXD4 MIR548H3 GC17P013426
GH17G013518 0.4 ENCODE 11.8 +24.8 24768 0.2 POLR2A MIR548H3 GC17P013426
GH17G013543 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -1.1 -1082 2.0 JUND BHLHE40 SIN3A MNT FOS ZBTB40 HS3ST3A1 MIR548H3 GC17P013587
GH17G013538 1.2 ENCODE dbSUPER 0.7 +3.4 3366 3.9 PKNOX1 TBL1XR1 ZFP64 RAD21 TCF12 ZNF766 GATA2 FOS CREM CEBPB HS3ST3A1 MIR548H3 GC17P013426
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548H3 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548H3 Gene

Chromosome:
17
Start:
13,543,529 bp from pter
End:
13,543,646 bp from pter
Size:
118 bases
Orientation:
Minus strand

Genomic View for MIR548H3 Gene

Genes around MIR548H3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548H3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548H3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548H3 Gene

ORGUL Member Location for MIR548H3 Gene

ORGUL Member Location for MIR548H3 gene

Proteins for MIR548H3 Gene

Post-translational modifications for MIR548H3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548H3 Gene

Domains & Families for MIR548H3 Gene

Gene Families for MIR548H3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548H3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548H3 Gene

Function for MIR548H3 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548H3 Gene

Localization for MIR548H3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548H3 Gene

Pathways & Interactions for MIR548H3 Gene

SuperPathways for MIR548H3 Gene

No Data Available

Interacting Proteins for MIR548H3 Gene

Gene Ontology (GO) - Biological Process for MIR548H3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548H3 Gene

Drugs & Compounds for MIR548H3 Gene

No Compound Related Data Available

Transcripts for MIR548H3 Gene

mRNA/cDNA for MIR548H3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548H3 Gene

No ASD Table

Relevant External Links for MIR548H3 Gene

GeneLoc Exon Structure for
MIR548H3
ECgene alternative splicing isoforms for
MIR548H3

Expression for MIR548H3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548H3 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548H3 Gene:

MIR548H3
genes like me logo Genes that share expression patterns with MIR548H3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548H3 Gene

Orthologs for MIR548H3 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548H3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 80 (a)
ManyToMany
Species where no ortholog for MIR548H3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548H3 Gene

ENSEMBL:
Gene Tree for MIR548H3 (if available)
TreeFam:
Gene Tree for MIR548H3 (if available)

Paralogs for MIR548H3 Gene

No data available for Paralogs for MIR548H3 Gene

Variants for MIR548H3 Gene

Sequence variations from dbSNP and Humsavar for MIR548H3 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000748035 -- 13,545,372(+) CCTCA(C/G)AGAGG intron-variant, upstream-variant-2KB
rs1003286515 -- 13,545,411(+) TCTGG(A/C)CTTTT intron-variant, upstream-variant-2KB
rs1003373496 -- 13,543,371(+) TGTAG(A/T)GTCAG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1003401043 -- 13,545,100(+) TTGTC(A/G)AATGA intron-variant, upstream-variant-2KB
rs1005786452 -- 13,544,966(+) ATCAA(C/T)TCTCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548H3 Gene

Variant ID Type Subtype PubMed ID
esv34170 CNV loss 18971310
esv3572409 CNV gain 25503493
nsv833375 CNV loss 17160897

Relevant External Links for MIR548H3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548H3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548H3 Gene

Disorders for MIR548H3 Gene

Relevant External Links for MIR548H3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548H3

No disorders were found for MIR548H3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548H3 Gene

Publications for MIR548H3 Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548H3 Gene

Sources for MIR548H3 Gene

Content
Loading form....