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Aliases for MIR548H2 Gene

Subcategory (RNA class) for MIR548H2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548H2 Gene

  • MicroRNA 548h-2 2 3
  • Hsa-Mir-548h-2 3
  • MIR548H-2 3
  • MIRN548H2 3

External Ids for MIR548H2 Gene

Previous Symbols for MIR548H2 Gene

  • MIRN548H2

Summaries for MIR548H2 Gene

Entrez Gene Summary for MIR548H2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548H2 Gene

MIR548H2 (MicroRNA 548h-2) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548H2 Gene

Genomics for MIR548H2 Gene

Genomic Location for MIR548H2 Gene

Start:
11,306,440 bp from pter
End:
11,306,527 bp from pter
Size:
88 bases
Orientation:
Minus strand

Genomic View for MIR548H2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548H2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548H2 Gene

ORGUL Member Location for MIR548H2 Gene

ORGUL Member Location for MIR548H2 gene

No data available for Regulatory Elements for MIR548H2 Gene

Proteins for MIR548H2 Gene

Post-translational modifications for MIR548H2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548H2 Gene

Domains for MIR548H2 Gene

Gene Families for MIR548H2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR548H2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR548H2 Gene

Function for MIR548H2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548H2 Gene

Localization for MIR548H2 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR548H2 Gene

Pathways for MIR548H2 Gene

SuperPathways for MIR548H2 Gene

No Data Available

Interacting Proteins for MIR548H2 Gene

Gene Ontology (GO) - Biological Process for MIR548H2 Gene

None

No data available for Pathways by source for MIR548H2 Gene

Transcripts for MIR548H2 Gene

mRNA/cDNA for MIR548H2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548H2 Gene

No ASD Table

Relevant External Links for MIR548H2 Gene

GeneLoc Exon Structure for
MIR548H2
ECgene alternative splicing isoforms for
MIR548H2

Expression for MIR548H2 Gene

mRNA expression in normal human tissues for MIR548H2 Gene

genes like me logo Genes that share expressions with MIR548H2: view

Orthologs for MIR548H2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548H2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 99 (a)
OneToOne
Species with no ortholog for MIR548H2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548H2 Gene

ENSEMBL:
Gene Tree for MIR548H2 (if available)
TreeFam:
Gene Tree for MIR548H2 (if available)

Paralogs for MIR548H2 Gene

No data available for Paralogs for MIR548H2 Gene

Variants for MIR548H2 Gene

Sequence variations from dbSNP and Humsavar for MIR548H2 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs4781062 -- 11,307,559(+) tgtgc(C/T)cttca upstream-variant-2KB
rs4781063 -- 11,308,022(+) gaagc(C/T)tggag upstream-variant-2KB
rs7204734 -- 11,308,511(+) ccttc(A/G)gaccc upstream-variant-2KB
rs11866335 -- 11,307,627(+) CTGGG(C/T)GTGGT upstream-variant-2KB
rs12600282 -- 11,308,009(+) gcatt(G/T)gtgcc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548H2 Gene

Variant ID Type Subtype PubMed ID
nsv4064 CNV Loss 18451855
esv32886 CNV Gain 17666407
nsv511102 CNV Complex 20534489
nsv4066 CNV Insertion 18451855
nsv244 CNV Insertion 15895083
esv1004315 CNV Insertion 20482838
esv33759 CNV Gain 17666407
esv2726060 CNV Deletion 23290073
nsv522472 CNV Loss 19592680
nsv877651 CNV Loss 21882294
dgv1521e1 CNV Complex 17122850
esv2678264 CNV Deletion 23128226
essv20845 CNV CNV 17122850
esv2726061 CNV Deletion 23290073
esv2726063 CNV Deletion 23290073
nsv517155 CNV Loss 19592680
dgv5276n71 CNV Loss 21882294
dgv621n27 CNV Loss 19166990
nsv877654 CNV Loss 21882294
esv25716 CNV Loss 19812545
nsv514175 CNV Loss 21397061
esv2672544 CNV Deletion 23128226
dgv622n27 CNV Loss 19166990
nsv877655 CNV Loss 21882294

Relevant External Links for MIR548H2 Gene

HapMap Linkage Disequilibrium report
MIR548H2

Disorders for MIR548H2 Gene

No disorders were found for MIR548H2 Gene.

No data available for UniProtKB/Swiss-Prot for MIR548H2 Gene

Publications for MIR548H2 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3

Products for MIR548H2 Gene

Sources for MIR548H2 Gene

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