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Aliases for MIR548G Gene

Subcategory (RNA class) for MIR548G Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548G Gene

  • MicroRNA 548g 2 3 5
  • Hsa-Mir-548g 3
  • MIRN548G 3

External Ids for MIR548G Gene

Previous HGNC Symbols for MIR548G Gene

  • MIRN548G

Previous GeneCards Identifiers for MIR548G Gene

  • GC00U923152
  • GC04M148486
  • GC04M148265

Summaries for MIR548G Gene

Entrez Gene Summary for MIR548G Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548G Gene

MIR548G (MicroRNA 548g) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548G Gene

Genomics for MIR548G Gene

Regulatory Elements for MIR548G Gene

Enhancers for MIR548G Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04F147370 1 Ensembl ENCODE 12.4 -26.6 -26648 2.5 SOX13 PKNOX1 JUN HLF CEBPB CEBPG EP300 RAD21 ATF2 NFIL3 MIR548G GC04P147361 RPL31P26
GH04F147312 0.8 Ensembl ENCODE 10.9 +31.9 31893 0.8 OSR2 PATZ1 GLIS1 BHLHE40 PRDM10 ZNF843 SP7 MIR548G GC04P147327 LOC105377476
GH04F147378 0.6 ENCODE 11.5 -34.3 -34297 0.1 CTCF JUND CEBPB CUX1 FOS RAD21 MIR548G GC04P147361 RPL31P26
GH04F147341 0.8 ENCODE 0.8 +4.0 3974 0.2 PKNOX1 INSM2 FEZF1 ZNF2 BCL11B HIC1 CTBP1 KLF8 TCF7L2 SCRT1 MIR548G GC04P147327
GH04F147340 0.5 ENCODE 0.8 +4.4 4374 0.2 ZNF202 JUND FOS PRMT9 MIR548G GC04P147327
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548G on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548G Gene

Chromosome:
4
Start:
147,344,629 bp from pter
End:
147,344,717 bp from pter
Size:
89 bases
Orientation:
Minus strand

Genomic View for MIR548G Gene

Genes around MIR548G on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548G Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548G Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548G Gene

ORGUL Member Location for MIR548G Gene

ORGUL Member Location for MIR548G gene

Proteins for MIR548G Gene

Post-translational modifications for MIR548G Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548G Gene

Domains & Families for MIR548G Gene

Gene Families for MIR548G Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548G: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548G Gene

Function for MIR548G Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548G Gene

Localization for MIR548G Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548G Gene

Pathways & Interactions for MIR548G Gene

SuperPathways for MIR548G Gene

No Data Available

Interacting Proteins for MIR548G Gene

Gene Ontology (GO) - Biological Process for MIR548G Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548G Gene

Transcripts for MIR548G Gene

mRNA/cDNA for MIR548G Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548G Gene

No ASD Table

Relevant External Links for MIR548G Gene

GeneLoc Exon Structure for
MIR548G
ECgene alternative splicing isoforms for
MIR548G

Expression for MIR548G Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548G Gene:

MIR548G
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548G Gene

Orthologs for MIR548G Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548G Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 99 (a)
OneToOne
Species where no ortholog for MIR548G was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548G Gene

ENSEMBL:
Gene Tree for MIR548G (if available)
TreeFam:
Gene Tree for MIR548G (if available)

Paralogs for MIR548G Gene

No data available for Paralogs for MIR548G Gene

Variants for MIR548G Gene

Sequence variations from dbSNP and Humsavar for MIR548G Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1005771 -- 147,346,421(-) ATTAG(A/T)GGTTA upstream-variant-2KB
rs111847490 -- 147,344,938(+) GGCTT(C/T)AAGAG upstream-variant-2KB
rs113765324 -- 147,345,917(+) CCACC(A/T)TGACT upstream-variant-2KB
rs114465095 -- 147,344,755(+) GTTGT(A/G)TAGAT upstream-variant-2KB
rs139249054 -- 147,346,381(+) TGAAA(C/T)AAAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548G Gene

Variant ID Type Subtype PubMed ID
nsv4540 CNV deletion 18451855
nsv830108 CNV loss 17160897

Relevant External Links for MIR548G Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548G

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548G Gene

Disorders for MIR548G Gene

Relevant External Links for MIR548G

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548G

No disorders were found for MIR548G Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548G Gene

Publications for MIR548G Gene

  1. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548G Gene

Sources for MIR548G Gene

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