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Aliases for MIR548D2 Gene

Subcategory (RNA class) for MIR548D2 Gene


Quality Score for this RNA gene is


Aliases for MIR548D2 Gene

  • MicroRNA 548d-2 5 2 3
  • Hsa-Mir-548d-2 3
  • MIRN548D2 3

External Ids for MIR548D2 Gene

Previous HGNC Symbols for MIR548D2 Gene

  • MIRN548D2

Previous GeneCards Identifiers for MIR548D2 Gene

  • GC17M062899
  • GC17M065467
  • GC17P065468

Summaries for MIR548D2 Gene

Entrez Gene Summary for MIR548D2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548D2 Gene

MIR548D2 (MicroRNA 548d-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548D2 Gene

Genomics for MIR548D2 Gene

Regulatory Elements for MIR548D2 Gene

Enhancers for MIR548D2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MIR548D2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548D2 Gene

67,471,489 bp from pter
67,471,585 bp from pter
97 bases
Minus strand

Genomic View for MIR548D2 Gene

Genes around MIR548D2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548D2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548D2 Gene

Proteins for MIR548D2 Gene

Post-translational modifications for MIR548D2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548D2 Gene

Domains & Families for MIR548D2 Gene

Gene Families for MIR548D2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548D2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548D2 Gene

Function for MIR548D2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548D2 Gene

Localization for MIR548D2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548D2 Gene

Pathways & Interactions for MIR548D2 Gene

SuperPathways for MIR548D2 Gene

No Data Available

Interacting Proteins for MIR548D2 Gene

Gene Ontology (GO) - Biological Process for MIR548D2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548D2 Gene

Drugs & Compounds for MIR548D2 Gene

No Compound Related Data Available

Transcripts for MIR548D2 Gene

mRNA/cDNA for MIR548D2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548D2 Gene

No ASD Table

Relevant External Links for MIR548D2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548D2 Gene

mRNA expression in normal human tissues for MIR548D2 Gene

genes like me logo Genes that share expression patterns with MIR548D2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR548D2 Gene

Orthologs for MIR548D2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548D2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 68 (a)
Species with no ortholog for MIR548D2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548D2 Gene

Gene Tree for MIR548D2 (if available)
Gene Tree for MIR548D2 (if available)

Paralogs for MIR548D2 Gene

No data available for Paralogs for MIR548D2 Gene

Variants for MIR548D2 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548D2 Gene

Variant ID Type Subtype PubMed ID
dgv834e1 CNV Complex 17122850
dgv835e1 CNV Complex 17122850
nsv428324 CNV Gain 18775914
dgv2648n71 CNV Gain 21882294
dgv2649n71 CNV Gain 21882294
dgv837e1 CNV Complex 17122850
dgv2654n71 CNV Gain 21882294
nsv821683 CNV Gain 15273396
dgv2657n71 CNV Gain 21882294
nsv471087 CNV Gain 18288195
dgv349n27 CNV Gain 19166990
dgv2658n71 CNV Gain 21882294
dgv2659n71 CNV Gain 21882294
nsv905656 CNV Gain 21882294
dgv2660n71 CNV Gain 21882294
dgv350n27 CNV Gain 19166990
nsv905663 CNV Gain 21882294
dgv2661n71 CNV Gain 21882294
dgv2662n71 CNV Gain 21882294
nsv817727 CNV Loss 17921354
nsv519620 CNV Loss 19592680
esv2714079 CNV Deletion 23290073
esv2714080 CNV Deletion 23290073

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR548D2 Gene

Disorders for MIR548D2 Gene

Relevant External Links for MIR548D2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548D2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548D2 Gene

Publications for MIR548D2 Gene

  1. Downregulation of PPARI^ by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential. (PMID: 24929254) Sun J. … Zhao G. (J Transl Med 2014) 3 67
  2. Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. (PMID: 23377640) (Am J Psychiatry 2013) 3
  3. MicroRNA miR-548d is a superior regulator in pancreatic cancer. (PMID: 21946813) Heyn H. … Beger C. (Pancreas 2012) 3
  4. Preliminary validation of ERBB2 expression regulated by miR-548d-3p and miR-559. (PMID: 19486885) Chen H. … Chen Z.T. (Biochem. Biophys. Res. Commun. 2009) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR548D2 Gene

Sources for MIR548D2 Gene