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Aliases for MIR548D1 Gene

Subcategory (RNA class) for MIR548D1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548D1 Gene

  • MicroRNA 548d-1 2 3
  • Hsa-Mir-548d-1 3 5
  • MIRN548D1 3

External Ids for MIR548D1 Gene

Previous HGNC Symbols for MIR548D1 Gene

  • MIRN548D1

Previous GeneCards Identifiers for MIR548D1 Gene

  • GC08M124430
  • GC08P124362
  • GC08M124364

Summaries for MIR548D1 Gene

Entrez Gene Summary for MIR548D1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548D1 Gene

MIR548D1 (MicroRNA 548d-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548D1 Gene

Genomics for MIR548D1 Gene

Regulatory Elements for MIR548D1 Gene

Enhancers for MIR548D1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR548D1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548D1 Gene

Chromosome:
8
Start:
123,348,034 bp from pter
End:
123,348,130 bp from pter
Size:
97 bases
Orientation:
Minus strand

Genomic View for MIR548D1 Gene

Genes around MIR548D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548D1 Gene

Proteins for MIR548D1 Gene

Post-translational modifications for MIR548D1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548D1 Gene

Domains & Families for MIR548D1 Gene

Gene Families for MIR548D1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548D1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548D1 Gene

Function for MIR548D1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548D1 Gene

Localization for MIR548D1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548D1 Gene

Pathways & Interactions for MIR548D1 Gene

SuperPathways for MIR548D1 Gene

No Data Available

Interacting Proteins for MIR548D1 Gene

Gene Ontology (GO) - Biological Process for MIR548D1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548D1 Gene

Drugs & Compounds for MIR548D1 Gene

No Compound Related Data Available

Transcripts for MIR548D1 Gene

mRNA/cDNA for MIR548D1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548D1 Gene

No ASD Table

Relevant External Links for MIR548D1 Gene

GeneLoc Exon Structure for
MIR548D1
ECgene alternative splicing isoforms for
MIR548D1

Expression for MIR548D1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548D1 Gene:

MIR548D1
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548D1 Gene

Orthologs for MIR548D1 Gene

Evolution for MIR548D1 Gene

ENSEMBL:
Gene Tree for MIR548D1 (if available)
TreeFam:
Gene Tree for MIR548D1 (if available)

No data available for Orthologs for MIR548D1 Gene

Paralogs for MIR548D1 Gene

No data available for Paralogs for MIR548D1 Gene

Variants for MIR548D1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548D1 Gene

Variant ID Type Subtype PubMed ID
nsv831449 CNV loss 17160897

Relevant External Links for MIR548D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR548D1 Gene

Disorders for MIR548D1 Gene

Relevant External Links for MIR548D1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548D1

No disorders were found for MIR548D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548D1 Gene

Publications for MIR548D1 Gene

  1. Downregulation of PPARI^ by miR-548d-5p suppresses the adipogenic differentiation of human bone marrow mesenchymal stem cells and enhances their osteogenic potential. (PMID: 24929254) Sun J. … Zhao G. (J Transl Med 2014) 3 65
  2. MicroRNA miR-548d is a superior regulator in pancreatic cancer. (PMID: 21946813) Heyn H. … Beger C. (Pancreas 2012) 3 65
  3. Preliminary validation of ERBB2 expression regulated by miR-548d-3p and miR-559. (PMID: 19486885) Chen H. … Chen Z.T. (Biochem. Biophys. Res. Commun. 2009) 3 65
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 65
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 65

Products for MIR548D1 Gene

Sources for MIR548D1 Gene

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