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Aliases for MIR548C Gene

Subcategory (RNA class) for MIR548C Gene


Quality Score for this RNA gene is


Aliases for MIR548C Gene

  • MicroRNA 548c 2 3 5
  • Hsa-Mir-548c 3
  • MIRN548C 3

External Ids for MIR548C Gene

ORGUL Members for MIR548C Gene

Previous HGNC Symbols for MIR548C Gene

  • MIRN548C

Previous GeneCards Identifiers for MIR548C Gene

  • GC12P063303
  • GC12P065016

Summaries for MIR548C Gene

Entrez Gene Summary for MIR548C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548C Gene

MIR548C (MicroRNA 548c) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548C Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548C Gene

Genomics for MIR548C Gene

Regulatory Elements for MIR548C Gene

Enhancers for MIR548C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H064664 2 FANTOM5 Ensembl ENCODE dbSUPER 12.2 +52.8 52797 21.8 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A FEZF1 ZNF2 YY1 LEMD3 TBK1 RASSF3 LOC100420899 LOC105369804 MIR548C ENSG00000223294 GNS C12orf66 ENSG00000256314
GH12H064655 1.5 Ensembl ENCODE dbSUPER 11.9 +34.9 34885 4.6 FOXA2 ZFP64 ARID4B FEZF1 TCF12 GATA2 MXD4 PPARG NFIL3 MIER3 RASSF3 MIR548C LOC105369804 ENSG00000223294 ENSG00000256314 ENSG00000280320
GH12H064649 1.2 Ensembl ENCODE dbSUPER 11.9 +29.5 29530 4.7 FEZF1 ZNF2 ZNF121 ZSCAN5C FOS RCOR1 ZNF362 GFI1B OVOL3 ZEB2 MIR548C LOC105369804 RASSF3 ENSG00000223294 ENSG00000256314 ENSG00000225195
GH12H064594 1.2 FANTOM5 Ensembl ENCODE 11.6 -26.8 -26811 2.2 HLF CEBPG GABPA SREBF1 NFIL3 ZNF766 POLR2A CEBPA FOS MYC RASSF3 MIR548C TBK1 GC12P064587 LOC105369804
GH12H064660 1.2 Ensembl ENCODE dbSUPER 11.5 +38.4 38387 1.1 NR2F1 JUNB DPF2 BATF JUND BCL11A EED TARDBP IKZF1 ATF7 RASSF3 LOC105369804 MIR548C ENSG00000256314 ENSG00000280320
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548C on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548C Gene

Genomic Locations for MIR548C Gene
97 bases
Plus strand

Genomic View for MIR548C Gene

Genes around MIR548C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548C Gene

Proteins for MIR548C Gene

Post-translational modifications for MIR548C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548C Gene

Domains & Families for MIR548C Gene

Gene Families for MIR548C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548C Gene

Function for MIR548C Gene

Gene Ontology (GO) - Molecular Function for MIR548C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 28111633
genes like me logo Genes that share ontologies with MIR548C: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548C Gene

Localization for MIR548C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548C Gene

Pathways & Interactions for MIR548C Gene

SuperPathways for MIR548C Gene

No Data Available

Interacting Proteins for MIR548C Gene

Gene Ontology (GO) - Biological Process for MIR548C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010628 positive regulation of gene expression IGI 28111633
GO:0010629 negative regulation of gene expression IDA 28111633
GO:0035195 gene silencing by miRNA IDA 28111633
GO:0060045 positive regulation of cardiac muscle cell proliferation IDA 28111633
genes like me logo Genes that share ontologies with MIR548C: view

No data available for Pathways by source and SIGNOR curated interactions for MIR548C Gene

Drugs & Compounds for MIR548C Gene

No Compound Related Data Available

Transcripts for MIR548C Gene

mRNA/cDNA for MIR548C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548C Gene

No ASD Table

Relevant External Links for MIR548C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548C Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548C Gene:

genes like me logo Genes that share expression patterns with MIR548C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548C Gene

Orthologs for MIR548C Gene

Evolution for MIR548C Gene

Gene Tree for MIR548C (if available)
Gene Tree for MIR548C (if available)

No data available for Orthologs for MIR548C Gene

Paralogs for MIR548C Gene

No data available for Paralogs for MIR548C Gene

Variants for MIR548C Gene

Sequence variations from dbSNP and Humsavar for MIR548C Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1001464412 -- 64,621,809(+) AGGCT(A/G)ACATC intron-variant, upstream-variant-2KB
rs1002254885 -- 64,620,522(+) TACTA(C/T)ACTGA intron-variant, upstream-variant-2KB
rs1002693057 -- 64,620,636(+) CCAAA(C/T)ATTGG intron-variant, upstream-variant-2KB
rs1003112774 -- 64,620,875(+) AGAAA(A/G)AAAAC intron-variant, upstream-variant-2KB
rs1004319905 -- 64,620,884(+) ACTTC(A/G)ATAAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548C Gene

Variant ID Type Subtype PubMed ID
nsv832444 CNV loss 17160897
nsv832443 CNV loss 17160897
dgv2682n54 CNV gain 21841781

Relevant External Links for MIR548C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548C Gene

Disorders for MIR548C Gene

Relevant External Links for MIR548C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548C Gene

Publications for MIR548C Gene

  1. MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist. (PMID: 26762267) Sun X … Zhang H (Journal of experimental & clinical cancer research : CR 2016) 3 60
  2. MicroRNAs regulating meis1 expression and inducing cardiomyocyte proliferation. (PMID: 28111633) Pandey R … Ahmed RP (Cardiovascular regenerative medicine 2016) 3 60
  3. Dysregulated MicroRNA Expression and Chronic Lung Allograft Rejection in Recipients With Antibodies to Donor HLA. (PMID: 25649290) Xu Z … Mohanakumar T (American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2015) 3 60
  4. MicroRNA Profile in Response to Doxorubicin Treatment in Breast Cancer. (PMID: 25802200) Tormo E … Eroles P (Journal of cellular biochemistry 2015) 3 60
  5. The Role of hsa-miR-548l Dysregulation as a Putative Modifier Factor for Glaucoma-Associated FOXC1 Mutations. (PMID: 25809640) Medina-Trillo C … Escribano J (MicroRNA (Shariqah, United Arab Emirates) 2015) 3 60

Products for MIR548C Gene

Sources for MIR548C Gene

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