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Aliases for MIR548C Gene

Subcategory (RNA class) for MIR548C Gene


Quality Score for this RNA gene is


Aliases for MIR548C Gene

  • MicroRNA 548c 2 3 5
  • Hsa-Mir-548c 3
  • MIRN548C 3

External Ids for MIR548C Gene

ORGUL Members for MIR548C Gene

Previous HGNC Symbols for MIR548C Gene

  • MIRN548C

Previous GeneCards Identifiers for MIR548C Gene

  • GC12P063303
  • GC12P065016

Summaries for MIR548C Gene

Entrez Gene Summary for MIR548C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548C Gene

MIR548C (MicroRNA 548c) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548C Gene

Genomics for MIR548C Gene

Regulatory Elements for MIR548C Gene

Enhancers for MIR548C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F064649 1.2 FANTOM5 Ensembl ENCODE 12.2 +45.4 45434 36.5 HDGF PKNOX1 ARNT MLX ZFP64 SIN3A ARID4B FEZF1 ZNF2 YY1 RASSF3 MSRB3 LOC105369804 MIR548C ENSG00000223294 LOC100507065 LEMD3 GNS C12orf66 TBK1
GH12F064687 0.2 ENCODE 12.1 +65.8 65782 2.5 OSR2 LOC105369804 MIR548C RASSF3 ENSG00000223294 ENSG00000280320 ENSG00000256314
GH12F064643 0.2 Ensembl 12 +21.3 21292 1.6 RASSF3 MIR548C LOC105369804 ENSG00000223294 ENSG00000256314 ENSG00000225195
GH12F064594 1.3 FANTOM5 Ensembl ENCODE 11.6 -25.2 -25209 5.4 HDAC1 LEF1 PKNOX1 CEBPG ZNF316 FOXK2 GATA2 NFE2 FOS SMARCE1 RASSF3 MIR548C TBK1 LOC105369804 GC12P064587
GH12F064595 0.2 Ensembl 11.6 -28.3 -28309 0.4 ZNF121 MIR548C GC12P064587 LOC105369804
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548C on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548C Gene

64,622,509 bp from pter
64,622,605 bp from pter
97 bases
Plus strand

Genomic View for MIR548C Gene

Genes around MIR548C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548C Gene

Proteins for MIR548C Gene

Post-translational modifications for MIR548C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548C Gene

Domains & Families for MIR548C Gene

Gene Families for MIR548C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548C Gene

Function for MIR548C Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548C Gene

Localization for MIR548C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548C Gene

Pathways & Interactions for MIR548C Gene

SuperPathways for MIR548C Gene

No Data Available

Interacting Proteins for MIR548C Gene

Gene Ontology (GO) - Biological Process for MIR548C Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548C Gene

Transcripts for MIR548C Gene

mRNA/cDNA for MIR548C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548C Gene

No ASD Table

Relevant External Links for MIR548C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548C Gene

mRNA expression in normal human tissues for MIR548C Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548C Gene:

genes like me logo Genes that share expression patterns with MIR548C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548C Gene

Orthologs for MIR548C Gene

Evolution for MIR548C Gene

Gene Tree for MIR548C (if available)
Gene Tree for MIR548C (if available)

No data available for Orthologs for MIR548C Gene

Paralogs for MIR548C Gene

No data available for Paralogs for MIR548C Gene

Variants for MIR548C Gene

Sequence variations from dbSNP and Humsavar for MIR548C Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10128936 -- 64,620,825(+) TTTAA(A/G)TTTCA intron-variant, upstream-variant-2KB
rs111530094 -- 64,621,227(+) CACTG(C/T)GCCTG intron-variant, upstream-variant-2KB
rs11175470 -- 64,621,092(+) CACTA(C/T)GCCCT intron-variant, upstream-variant-2KB
rs113292202 -- 64,622,394(+) GTATT(A/G)AAAAA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs113908831 -- 64,621,228(+) ACTGC(A/G)CCTGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548C Gene

Variant ID Type Subtype PubMed ID
dgv2682n54 CNV gain 21841781
nsv832443 CNV loss 17160897
nsv832444 CNV loss 17160897

Relevant External Links for MIR548C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548C Gene

Disorders for MIR548C Gene

Relevant External Links for MIR548C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548C Gene

Publications for MIR548C Gene

  1. MiR-548c impairs migration and invasion of endometrial and ovarian cancer cells via downregulation of Twist. (PMID: 26762267) Sun X. … Zhang H. (J. Exp. Clin. Cancer Res. 2016) 3 64
  2. Dysregulated MicroRNA Expression and Chronic Lung Allograft Rejection in Recipients With Antibodies to Donor HLA. (PMID: 25649290) Xu Z. … Mohanakumar T. (Am. J. Transplant. 2015) 3 64
  3. MicroRNA Profile in Response to Doxorubicin Treatment in Breast Cancer. (PMID: 25802200) Tormo E. … Eroles P. (J. Cell. Biochem. 2015) 3 64
  4. The Role of hsa-miR-548l Dysregulation as a Putative Modifier Factor for Glaucoma-Associated FOXC1 Mutations. (PMID: 25809640) Medina-Trillo C. … Escribano J. (Microrna 2015) 3 64
  5. Evaluation of BRCA1-related molecular features and microRNAs as prognostic factors for triple negative breast cancers. (PMID: 26490435) Boukerroucha M. … Bours V. (BMC Cancer 2015) 3 64

Products for MIR548C Gene

Sources for MIR548C Gene

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