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Aliases for MIR548B Gene

Subcategory (RNA class) for MIR548B Gene


Quality Score for this RNA gene is


Aliases for MIR548B Gene

  • MicroRNA 548b 2 3
  • Hsa-Mir-548b 3
  • MIRN548B 3

External Ids for MIR548B Gene

Previous HGNC Symbols for MIR548B Gene

  • MIRN548B

Previous GeneCards Identifiers for MIR548B Gene

  • GC06M119432
  • GC20M050018

Summaries for MIR548B Gene

Entrez Gene Summary for MIR548B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548B Gene

MIR548B (MicroRNA 548b) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR548B Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR548B Gene

Genomics for MIR548B Gene

Genomic Location for MIR548B Gene

119,069,047 bp from pter
119,069,143 bp from pter
97 bases
Minus strand

Genomic View for MIR548B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548B Gene

ORGUL Member Location for MIR548B Gene

ORGUL Member Location for MIR548B gene

No data available for Regulatory Elements for MIR548B Gene

Proteins for MIR548B Gene

Post-translational modifications for MIR548B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548B Gene

Domains for MIR548B Gene

Gene Families for MIR548B Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548B Gene

Function for MIR548B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548B Gene

Localization for MIR548B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548B Gene

Pathways for MIR548B Gene

SuperPathways for MIR548B Gene

No Data Available

Interacting Proteins for MIR548B Gene

Gene Ontology (GO) - Biological Process for MIR548B Gene


No data available for Pathways by source for MIR548B Gene

Transcripts for MIR548B Gene

mRNA/cDNA for MIR548B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548B Gene

No ASD Table

Relevant External Links for MIR548B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548B Gene

mRNA expression in normal human tissues for MIR548B Gene

genes like me logo Genes that share expressions with MIR548B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR548B Gene

Orthologs for MIR548B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-548b 36
  • 98 (a)
Species with no ortholog for MIR548B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548B Gene

Gene Tree for MIR548B (if available)
Gene Tree for MIR548B (if available)

Paralogs for MIR548B Gene

No data available for Paralogs for MIR548B Gene

Variants for MIR548B Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548B Gene

Variant ID Type Subtype PubMed ID
nsv528632 CNV Loss 19592680

Relevant External Links for MIR548B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR548B Gene

Disorders for MIR548B Gene

No disorders were found for MIR548B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR548B Gene

Publications for MIR548B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Axl-altered microRNAs regulate tumorigenicity and gefitinib resistance in lung cancer. (PMID: 24832599) Wang Y. … Cai H. (Cell Death Dis 2014) 3

Products for MIR548B Gene

Sources for MIR548B Gene

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