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Aliases for MIR548AW Gene

Subcategory (RNA class) for MIR548AW Gene


Quality Score for this RNA gene is


Aliases for MIR548AW Gene

  • MicroRNA 548aw 2 3 5
  • Hsa-Mir-548aw 3

External Ids for MIR548AW Gene

Previous GeneCards Identifiers for MIR548AW Gene

  • GC09U901745
  • GC09P135827

Summaries for MIR548AW Gene

Entrez Gene Summary for MIR548AW Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AW Gene

MIR548AW (MicroRNA 548aw) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AW Gene

Genomics for MIR548AW Gene

Regulatory Elements for MIR548AW Gene

Enhancers for MIR548AW Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F132946 0.5 ENCODE 0.8 +0.9 875 1.1 JUN TEAD4 FEZF1 RARA TEAD3 GLIS2 PATZ1 PRDM10 ZNF600 NR2F6 TTF1 MIR548AW GC09P132954
GH09F132945 0.4 ENCODE 0.8 +0.2 210 0.1 RFX1 ID3 MIR548AW GC09P132954
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548AW on UCSC Golden Path with GeneCards custom track

Promoters for MIR548AW Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR548AW Gene

132,945,707 bp from pter
132,945,771 bp from pter
65 bases
Plus strand

Genomic View for MIR548AW Gene

Genes around MIR548AW on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AW Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AW Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AW Gene

Proteins for MIR548AW Gene

Post-translational modifications for MIR548AW Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AW Gene

Domains & Families for MIR548AW Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AW Gene

Function for MIR548AW Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AW Gene

Localization for MIR548AW Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AW Gene

Pathways & Interactions for MIR548AW Gene

SuperPathways for MIR548AW Gene

No Data Available

Interacting Proteins for MIR548AW Gene

Gene Ontology (GO) - Biological Process for MIR548AW Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AW Gene

Transcripts for MIR548AW Gene

mRNA/cDNA for MIR548AW Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AW Gene

No ASD Table

Relevant External Links for MIR548AW Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AW Gene

mRNA expression in normal human tissues for MIR548AW Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AW Gene:

genes like me logo Genes that share expression patterns with MIR548AW: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548AW Gene

Orthologs for MIR548AW Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AW Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 35
  • 49 (a)
Species where no ortholog for MIR548AW was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AW Gene

Gene Tree for MIR548AW (if available)
Gene Tree for MIR548AW (if available)

Paralogs for MIR548AW Gene

No data available for Paralogs for MIR548AW Gene

Variants for MIR548AW Gene

Sequence variations from dbSNP and Humsavar for MIR548AW Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs796053468 Uncertain significance 132,944,543(-) CGGTG(A/G)GTGAG intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs111567443 -- 132,944,031(+) CAGCG(A/G)AGACA intron-variant, upstream-variant-2KB
rs11243938 -- 132,945,399(+) ACAAG(G/T)CTTTA upstream-variant-2KB
rs11243939 -- 132,945,400(+) CAAGG(C/T)TTTAA upstream-variant-2KB
rs11243940 -- 132,945,985(+) TGAAA(A/G)GGCCC intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AW Gene

Variant ID Type Subtype PubMed ID
esv2739138 CNV deletion 23290073
nsv509329 CNV insertion 20534489
nsv6745 CNV insertion 18451855
nsv831743 CNV loss 17160897

Relevant External Links for MIR548AW Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AW Gene

Disorders for MIR548AW Gene

Relevant External Links for MIR548AW

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548AW Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AW Gene

Publications for MIR548AW Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A. … Wang Y. (PLoS ONE 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548AW Gene

Sources for MIR548AW Gene

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