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Aliases for MIR548AW Gene

Subcategory (RNA class) for MIR548AW Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AW Gene

  • MicroRNA 548aw 2 3 5
  • Hsa-Mir-548aw 3

External Ids for MIR548AW Gene

Previous GeneCards Identifiers for MIR548AW Gene

  • GC09U901745
  • GC09P135827

Summaries for MIR548AW Gene

Entrez Gene Summary for MIR548AW Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AW Gene

MIR548AW (MicroRNA 548aw) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AW Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AW Gene

Genomics for MIR548AW Gene

GeneHancer (GH) Regulatory Elements for MIR548AW Gene

Promoters and enhancers for MIR548AW Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I132943 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 550.8 -1.2 -1172 2.5 CLOCK FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC TSC1 GFI1B MIR548AW SETX MED22 GTF3C5 TTF1 DDX31 MED27 RPL7A
GH09I132946 Enhancer 0.9 Ensembl ENCODE 550.8 +0.9 875 1.1 JUN ZSCAN4 FEZF1 RARA TEAD3 HIC1 GLIS2 PATZ1 PRDM10 NR2F6 MIR548AW TSC1 MED22 TTF1 GFI1B GC09P132954
GH09I132945 Enhancer 0.4 ENCODE 550.8 +0.2 210 0.1 RFX1 ID3 MLLT1 GFI1B MIR548AW TSC1 GC09P132954
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR548AW on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AW Gene

Genomic Locations for MIR548AW Gene
chr9:132,945,707-132,945,771
(GRCh38/hg38)
Size:
65 bases
Orientation:
Plus strand
chr9:135,821,094-135,821,158
(GRCh37/hg19)

Genomic View for MIR548AW Gene

Genes around MIR548AW on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AW Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AW Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AW Gene

Proteins for MIR548AW Gene

Post-translational modifications for MIR548AW Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AW Gene

Domains & Families for MIR548AW Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AW Gene

Function for MIR548AW Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AW Gene

Localization for MIR548AW Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AW Gene

Pathways & Interactions for MIR548AW Gene

SuperPathways for MIR548AW Gene

No Data Available

Interacting Proteins for MIR548AW Gene

Gene Ontology (GO) - Biological Process for MIR548AW Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AW Gene

Drugs & Compounds for MIR548AW Gene

No Compound Related Data Available

Transcripts for MIR548AW Gene

mRNA/cDNA for MIR548AW Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AW Gene

No ASD Table

Relevant External Links for MIR548AW Gene

GeneLoc Exon Structure for
MIR548AW
ECgene alternative splicing isoforms for
MIR548AW

Expression for MIR548AW Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548AW Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AW Gene:

MIR548AW
genes like me logo Genes that share expression patterns with MIR548AW: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AW Gene

Orthologs for MIR548AW Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AW Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 34
  • 49 (a)
ManyToMany
Species where no ortholog for MIR548AW was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AW Gene

ENSEMBL:
Gene Tree for MIR548AW (if available)
TreeFam:
Gene Tree for MIR548AW (if available)

Paralogs for MIR548AW Gene

No data available for Paralogs for MIR548AW Gene

Variants for MIR548AW Gene

Sequence variations from dbSNP and Humsavar for MIR548AW Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1034967304 uncertain-significance, Tuberous sclerosis syndrome, Focal cortical dysplasia type II 132,944,626(+) C/T upstream_transcript_variant
rs571288003 likely-benign, Tuberous sclerosis syndrome, Focal cortical dysplasia type II 132,944,641(+) C/A/T upstream_transcript_variant
rs886063626 uncertain-significance, Focal cortical dysplasia type II, Tuberous sclerosis syndrome 132,944,565(+) T/C upstream_transcript_variant
rs886063627 uncertain-significance, Focal cortical dysplasia type II, Tuberous sclerosis syndrome 132,944,573(+) T/A upstream_transcript_variant
rs907109902 uncertain-significance, Tuberous sclerosis syndrome, Focal cortical dysplasia type II 132,944,613(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548AW Gene

Variant ID Type Subtype PubMed ID
esv2739138 CNV deletion 23290073
nsv509329 CNV insertion 20534489
nsv6745 CNV insertion 18451855
nsv831743 CNV loss 17160897

Additional Variant Information for MIR548AW Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AW

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AW Gene

Disorders for MIR548AW Gene

Additional Disease Information for MIR548AW

No disorders were found for MIR548AW Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AW Gene

Publications for MIR548AW Gene

  1. MicroRNAs associated with metastatic prostate cancer. (PMID: 21980368) Watahiki A … Wang Y (PloS one 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR548AW Gene

Sources for MIR548AW Gene

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