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Aliases for MIR548AV Gene

Subcategory (RNA class) for MIR548AV Gene


Quality Score for this RNA gene is


Aliases for MIR548AV Gene

  • MicroRNA 548av 2 3 5
  • Hsa-Mir-548av 3

External Ids for MIR548AV Gene

Previous GeneCards Identifiers for MIR548AV Gene

  • GC18U900696
  • GC18M070521

Summaries for MIR548AV Gene

Entrez Gene Summary for MIR548AV Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AV Gene

MIR548AV (MicroRNA 548av) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AV Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AV Gene

Genomics for MIR548AV Gene

Regulatory Elements for MIR548AV Gene

Enhancers for MIR548AV Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18H072846 0.5 ENCODE 0.4 +5.2 5177 2 CEBPB JUNB BATF MIR548AV RNA5SP460
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548AV on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548AV Gene

72,853,321 bp from pter
72,853,382 bp from pter
62 bases
Minus strand

Genomic View for MIR548AV Gene

Genes around MIR548AV on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AV Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AV Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AV Gene

ORGUL Member Location for MIR548AV Gene

ORGUL Member Location for MIR548AV gene

Proteins for MIR548AV Gene

Post-translational modifications for MIR548AV Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AV Gene

Domains & Families for MIR548AV Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AV Gene

Function for MIR548AV Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR548AV
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AV Gene

Localization for MIR548AV Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AV Gene

Pathways & Interactions for MIR548AV Gene

SuperPathways for MIR548AV Gene

No Data Available

Interacting Proteins for MIR548AV Gene

Gene Ontology (GO) - Biological Process for MIR548AV Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AV Gene

Drugs & Compounds for MIR548AV Gene

No Compound Related Data Available

Transcripts for MIR548AV Gene

mRNA/cDNA for MIR548AV Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR548AV
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AV Gene

No ASD Table

Relevant External Links for MIR548AV Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AV Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AV Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AV Gene

Orthologs for MIR548AV Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AV Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 49 (a)
-- 34
  • 35 (a)
Species where no ortholog for MIR548AV was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AV Gene

Gene Tree for MIR548AV (if available)
Gene Tree for MIR548AV (if available)

Paralogs for MIR548AV Gene

No data available for Paralogs for MIR548AV Gene

Variants for MIR548AV Gene

Sequence variations from dbSNP and Humsavar for MIR548AV Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs1000023769 -- 72,854,461(+) CCACA(A/G)GGAAG intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs1001639659 -- 72,853,865(+) AATAC(A/G)AAGAT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1003074927 -- 72,852,958(+) CTCCC(A/G)AGTAG intron-variant, downstream-variant-500B
rs1003953779 -- 72,852,926(+) CTCCC(A/G)GATTC intron-variant, downstream-variant-500B
rs1004245943 -- 72,853,345(+) TGCCA(G/T)TAAAG intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548AV Gene

Variant ID Type Subtype PubMed ID
esv34051 CNV loss 18971310
esv3893139 CNV gain 25118596
nsv483119 CNV loss 15286789

Relevant External Links for MIR548AV Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AV Gene

Disorders for MIR548AV Gene

Relevant External Links for MIR548AV

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548AV Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AV Gene

Publications for MIR548AV Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR548AV Gene

Sources for MIR548AV Gene

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