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Aliases for MIR548AU Gene

Subcategory (RNA class) for MIR548AU Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AU Gene

  • MicroRNA 548au 2 3 5
  • Hsa-Mir-548au 3

External Ids for MIR548AU Gene

Previous GeneCards Identifiers for MIR548AU Gene

  • GC09U901752

Summaries for MIR548AU Gene

Entrez Gene Summary for MIR548AU Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AU Gene

MIR548AU (MicroRNA 548au) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AU Gene

Genomics for MIR548AU Gene

Regulatory Elements for MIR548AU Gene

Enhancers for MIR548AU Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G093593 1 ENCODE dbSUPER 0.7 -0.9 -851 1.7 HDAC1 CTCF PKNOX1 KLF1 ETV1 ZMYM3 ZIC2 ZNF316 POLR2A EGR1 RNU6-829P ENSG00000227603 MIR548AU PHF2
GH09G093594 0.9 ENCODE dbSUPER 0.7 -2.2 -2228 0.2 CTCF RFX1 SAP130 ARID4B RAD21 ZNF48 ZNF579 ZNF580 RNU6-829P ENSG00000227603 MIR548AU PHF2
GH09G093592 0.8 ENCODE dbSUPER 0.7 -2.0 -2018 0.2 ZNF579 CTCF SAP130 ARID4B ZNF580 RAD21 ZNF48 RNU6-829P ENSG00000227603 MIR548AU PHF2
GH09G093588 1.3 Ensembl ENCODE dbSUPER 0.4 -5.4 -5366 1.8 ELF3 SOX13 DRAP1 MXI1 ZNF792 SAP130 ARID4B CEBPG RAD21 ZNF48 RNU6-829P ENSG00000227603 MIR548AU PHF2
GH09G093580 1.3 Ensembl ENCODE dbSUPER 0.4 -13.2 -13197 2.5 FOXA2 PKNOX1 ARID4B SIN3A RAD21 ZNF48 FOS USF2 ZEB2 NR2F2 ENSG00000227603 PHF2 MIR548AU
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548AU on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548AU Gene

Chromosome:
9
Start:
93,594,841 bp from pter
End:
93,594,894 bp from pter
Size:
54 bases
Orientation:
Plus strand

Genomic View for MIR548AU Gene

Genes around MIR548AU on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AU Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AU Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AU Gene

Proteins for MIR548AU Gene

Post-translational modifications for MIR548AU Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AU Gene

Domains & Families for MIR548AU Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AU Gene

Function for MIR548AU Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AU Gene

Localization for MIR548AU Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AU Gene

Pathways & Interactions for MIR548AU Gene

SuperPathways for MIR548AU Gene

No Data Available

Interacting Proteins for MIR548AU Gene

Gene Ontology (GO) - Biological Process for MIR548AU Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AU Gene

Transcripts for MIR548AU Gene

mRNA/cDNA for MIR548AU Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AU Gene

No ASD Table

Relevant External Links for MIR548AU Gene

GeneLoc Exon Structure for
MIR548AU
ECgene alternative splicing isoforms for
MIR548AU

Expression for MIR548AU Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AU Gene:

MIR548AU
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AU Gene

Orthologs for MIR548AU Gene

Evolution for MIR548AU Gene

ENSEMBL:
Gene Tree for MIR548AU (if available)
TreeFam:
Gene Tree for MIR548AU (if available)

No data available for Orthologs for MIR548AU Gene

Paralogs for MIR548AU Gene

No data available for Paralogs for MIR548AU Gene

Variants for MIR548AU Gene

Sequence variations from dbSNP and Humsavar for MIR548AU Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1002399879 -- 93,592,920(+) CAACT(A/G)GAGGA intron-variant, upstream-variant-2KB
rs1002668419 -- 93,594,140(+) TCACC(C/G)TTCCG intron-variant, upstream-variant-2KB
rs1002720605 -- 93,593,793(+) AACAC(C/T)ACACA intron-variant, upstream-variant-2KB
rs1003811710 -- 93,594,330(+) GAAAA(C/G)GGCCC intron-variant, upstream-variant-2KB
rs1004176660 -- 93,592,905(+) CCCAG(A/G)CTCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AU Gene

Variant ID Type Subtype PubMed ID
dgv19n6 CNV deletion 16902084
dgv4034n100 CNV gain 25217958
dgv6988n54 CNV loss 21841781
esv1223356 CNV deletion 17803354
esv2164871 CNV deletion 18987734
esv23336 CNV loss 19812545
esv2540661 CNV deletion 19546169
esv2671579 CNV deletion 23128226
esv2674728 CNV deletion 23128226
esv2676455 CNV deletion 23128226
esv2720482 CNV deletion 23290073
esv2720493 CNV deletion 23290073
esv2762271 CNV loss 21179565
esv3305769 CNV mobile element insertion 20981092
esv3372818 CNV insertion 20981092
esv3559910 CNV deletion 23714750
esv3591887 CNV loss 21293372
esv3591888 CNV loss 21293372
esv3591890 CNV loss 21293372
esv9107 CNV loss 19470904
esv990602 CNV deletion 20482838
nsv1071610 CNV deletion 25765185
nsv1114124 CNV deletion 24896259
nsv1152379 CNV deletion 26484159
nsv1160839 CNV deletion 26073780
nsv213203 CNV deletion 16902084
nsv2870 CNV deletion 18451855
nsv471617 CNV gain 15918152
nsv480289 CNV novel sequence insertion 20440878
nsv507026 OTHER sequence alteration 20534489
nsv509311 CNV insertion 20534489
nsv528330 CNV gain 19592680
nsv824984 CNV gain 20364138
nsv955052 CNV deletion 24416366

Relevant External Links for MIR548AU Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AU

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AU Gene

Disorders for MIR548AU Gene

Relevant External Links for MIR548AU

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548AU

No disorders were found for MIR548AU Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AU Gene

Publications for MIR548AU Gene

  1. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) FriedlAonder M.R. … Rajewsky N. (Nucleic Acids Res. 2012) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548AU Gene

Sources for MIR548AU Gene

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