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MIR548AR Gene(RNA Gene)

MicroRNA 548ar

GCID:
GC13P114244
GIFtS:
13
Genes Participants
UDN Logo

Aliases for MIR548AR Gene

Subcategory (RNA class) for MIR548AR Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AR Gene

  • MicroRNA 548ar 2 3 5
  • Hsa-Mir-548ar 3

External Ids for MIR548AR Gene

Previous GeneCards Identifiers for MIR548AR Gene

  • GC13U900874
  • GC13P115011

Summaries for MIR548AR Gene

Entrez Gene Summary for MIR548AR Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AR Gene

MIR548AR (MicroRNA 548ar) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AR Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AR Gene

Genomics for MIR548AR Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR548AR Gene

Promoters and enhancers for MIR548AR Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH13I114234 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.4 -9.1 -9101 2 PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 CDC16 CHAMP1 UPF3A MIR548AR
GH13I114249 Enhancer 0.5 ENCODE dbSUPER 0.8 +4.7 4716 0.2 ZBTB33 MIR548AR CDC16 MIR4502 LOC105370384
GH13I114246 Enhancer 0.4 dbSUPER 0.8 +2.3 2273 1.2 PAF1 SCRT1 SCRT2 CDC16 MIR548AR MIR4502 LOC105370384
GH13I114237 Enhancer 0.8 ENCODE 0.4 -6.6 -6644 1 HDAC1 PKNOX1 TCF12 ZBTB11 USF2 REST ZEB2 ZNF592 MEF2D SMARCA4 CDC16 UPF3A CHAMP1 MIR548AR
GH13I114250 Enhancer 0.7 dbSUPER 0.4 +6.9 6939 1.1 NFATC3 ARNT E4F1 NCOA2 TCF12 NCOR1 TRIM24 PRDM10 ZNF639 AFF1 MIR548AR CDC16 MIR4502 LOC105370384
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR548AR on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AR Gene

Genomic Locations for MIR548AR Gene
chr13:114,244,505-114,244,561
(GRCh38/hg38)
Size:
57 bases
Orientation:
Plus strand
chr13:115,009,980-115,010,036
(GRCh37/hg19)

Genomic View for MIR548AR Gene

Genes around MIR548AR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AR Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR548AR Gene

Proteins for MIR548AR Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR548AR Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AR Gene

Domains & Families for MIR548AR Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AR Gene

Function for MIR548AR Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AR Gene

Localization for MIR548AR Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AR Gene

Pathways & Interactions for MIR548AR Gene

SuperPathways for MIR548AR Gene

PathCards logo More details on SuperPathways for MIR548AR
No Data Available

Interacting Proteins for MIR548AR Gene

Gene Ontology (GO) - Biological Process for MIR548AR Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AR Gene

Drugs & Compounds for MIR548AR Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR548AR Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR548AR Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AR Gene

No ASD Table

Relevant External Links for MIR548AR Gene

GeneLoc Exon Structure for
MIR548AR
ECgene alternative splicing isoforms for
MIR548AR

Expression for MIR548AR Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548AR Gene

mRNA expression in normal human tissues for MIR548AR Gene
mRNA expression by GTEx for MIR548AR Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AR Gene:

MIR548AR
genes like me logo Genes that share expression patterns with MIR548AR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AR Gene

Orthologs for MIR548AR Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AR Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia -- 34
  • 42 (a)
 ManyToMany
Species where no ortholog for MIR548AR was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AR Gene

ENSEMBL:
Gene Tree for MIR548AR (if available)
TreeFam:
Gene Tree for MIR548AR (if available)

Paralogs for MIR548AR Gene

No data available for Paralogs for MIR548AR Gene

Variants for MIR548AR Gene

Sequence variations from dbSNP and Humsavar for MIR548AR Gene

SNP ID Clin Chr 13 pos Variation AA Info Type
rs1000810305 -- 114,243,394(+) A/G upstream_transcript_variant
rs1000996944 -- 114,244,424(+) G/T upstream_transcript_variant
rs1001880815 -- 114,244,016(+) A/G upstream_transcript_variant
rs1004304921 -- 114,244,047(+) G/A upstream_transcript_variant
rs1004890729 -- 114,244,609(+) G/A downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548AR Gene

Variant ID Type Subtype PubMed ID
dgv1745n100 CNV gain 25217958
dgv1746n100 CNV gain 25217958
esv25715 CNV gain+loss 19812545
esv3633642 CNV gain 21293372
esv3633643 CNV gain 21293372
nsv1043111 CNV gain 25217958
nsv1050622 CNV gain 25217958
nsv456143 CNV gain 19166990
nsv563532 CNV gain 21841781
nsv832728 CNV gain 17160897

Additional Variant Information for MIR548AR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AR Gene

Disorders for MIR548AR Gene

Additional Disease Information for MIR548AR

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR548AR Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AR Gene

Publications for MIR548AR Gene

  1. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini AA … Barker JN (Nature communications 2014) 3 58
  2. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR548AR Gene

Sources for MIR548AR Gene

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