Aliases for MIR548AR Gene
Subcategory (RNA class) for MIR548AR Gene
Quality Score for this RNA gene is
External Ids for MIR548AR Gene
- HGNC: 43455
- Entrez Gene: 100847035
- Ensembl: ENSG00000264539
Previous GeneCards Identifiers for MIR548AR Gene
- GC13U900874
- GC13P115011
Summaries for MIR548AR Gene
-
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
GeneCards Summary for MIR548AR Gene
MIR548AR (MicroRNA 548ar) is an RNA Gene, and is affiliated with the miRNA class.
Additional gene information for MIR548AR Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AR Gene
Genomics for MIR548AR Gene
GeneHancer (GH) Regulatory Elements for MIR548AR Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH13I114234 | Promoter/Enhancer | 2 | EPDnew Ensembl ENCODE | 0.4 | -9.1 | -9101 | 2 | PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 | CDC16 CHAMP1 UPF3A MIR548AR | |
GH13I114249 | Enhancer | 0.5 | ENCODE dbSUPER | 0.8 | +4.7 | 4716 | 0.2 | ZBTB33 | MIR548AR CDC16 MIR4502 LOC105370384 | |
GH13I114246 | Enhancer | 0.4 | dbSUPER | 0.8 | +2.3 | 2273 | 1.2 | PAF1 SCRT1 SCRT2 | CDC16 MIR548AR MIR4502 LOC105370384 | |
GH13I114237 | Enhancer | 0.8 | ENCODE | 0.4 | -6.6 | -6644 | 1 | HDAC1 PKNOX1 TCF12 ZBTB11 USF2 REST ZEB2 ZNF592 MEF2D SMARCA4 | CDC16 UPF3A CHAMP1 MIR548AR | |
GH13I114250 | Enhancer | 0.7 | dbSUPER | 0.4 | +6.9 | 6939 | 1.1 | NFATC3 ARNT E4F1 NCOA2 TCF12 NCOR1 TRIM24 PRDM10 ZNF639 AFF1 | MIR548AR CDC16 MIR4502 LOC105370384 |
Regulatory Element Products
Genomic Locations for MIR548AR Gene
- chr13:114,244,505-114,244,561
- (GRCh38/hg38)
- Size:
- 57 bases
- Orientation:
- Plus strand
- chr13:115,009,980-115,010,036
- (GRCh37/hg19)
Genomic View for MIR548AR Gene
- Cytogenetic band:
-
- 13q34 by Ensembl
- 13q34 by Entrez Gene
- 13q34 by HGNC


RefSeq DNA sequence for MIR548AR Gene
Proteins for MIR548AR Gene
Post-translational modifications for MIR548AR Gene
Antibody Products
- Search GeneTex for Antibodies for MIR548AR
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MIR548AR
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- Search GeneTex for Proteins for MIR548AR
No data available for DME Specific Peptides for MIR548AR Gene
Domains & Families for MIR548AR Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AR Gene
Function for MIR548AR Gene
Animal Model Products
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-
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CRISPR Products
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- Applied Biological Materials CRISPR for MIR548AR
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MIR548AR
Inhibitory RNA Products
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Clone Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR548AR
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AR Gene
Localization for MIR548AR Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AR Gene
Transcripts for MIR548AR Gene
mRNA/cDNA for MIR548AR Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MIR548AR
- Applied Biological Materials CRISPR for MIR548AR
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MIR548AR
Inhibitory RNA Products
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Clone Products
- GenScript: Custom all cDNA clones Services for MIR548AR
- VectorBuilder custom plasmid, inducible vectors for MIR548AR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR548AR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MIR548AR
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MIR548AR Gene
NURSA nuclear receptor signaling pathways regulating expression of MIR548AR Gene:
MIR548ARPrimer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AR Gene
Orthologs for MIR548AR Gene
This gene was present in the common ancestor of human and chimp.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | -- 34 |
|
ManyToMany |
- Species where no ortholog for MIR548AR was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for MIR548AR Gene
No data available for Paralogs for MIR548AR Gene
Variants for MIR548AR Gene
SNP ID | Clin | Chr 13 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000810305 | -- | 114,243,394(+) | A/G | upstream_transcript_variant | |
rs1000996944 | -- | 114,244,424(+) | G/T | upstream_transcript_variant | |
rs1001880815 | -- | 114,244,016(+) | A/G | upstream_transcript_variant | |
rs1004304921 | -- | 114,244,047(+) | G/A | upstream_transcript_variant | |
rs1004890729 | -- | 114,244,609(+) | G/A | downstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1745n100 | CNV | gain | 25217958 |
dgv1746n100 | CNV | gain | 25217958 |
esv25715 | CNV | gain+loss | 19812545 |
esv3633642 | CNV | gain | 21293372 |
esv3633643 | CNV | gain | 21293372 |
nsv1043111 | CNV | gain | 25217958 |
nsv1050622 | CNV | gain | 25217958 |
nsv456143 | CNV | gain | 19166990 |
nsv563532 | CNV | gain | 21841781 |
nsv832728 | CNV | gain | 17160897 |
Additional Variant Information for MIR548AR Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MIR548AR
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AR Gene
Disorders for MIR548AR Gene
Additional Disease Information for MIR548AR
No disorders were found for MIR548AR Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AR Gene
Publications for MIR548AR Gene
- Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini AA … Barker JN (Nature communications 2014) 3 58
- miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. (PMID: 21911355) Friedländer MR … Rajewsky N (Nucleic acids research 2012) 3 58
- miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
Products for MIR548AR Gene
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MIR548AR
- VectorBuilder custom plasmid, inducible vectors for MIR548AR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MIR548AR
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MIR548AR
- Search GeneTex for Proteins for MIR548AR
Sources for MIR548AR Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
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- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
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- (114) diseasecard
- (115) NIH Rare Diseases
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew