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Aliases for MIR548AM Gene

Subcategory (RNA class) for MIR548AM Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AM Gene

  • MicroRNA 548am 2 3 5
  • Hsa-Mir-548am 3

External Ids for MIR548AM Gene

Previous GeneCards Identifiers for MIR548AM Gene

  • GC0XU901744
  • GC0XP016646

Summaries for MIR548AM Gene

Entrez Gene Summary for MIR548AM Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AM Gene

MIR548AM (MicroRNA 548am) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AM Gene

Genomics for MIR548AM Gene

Regulatory Elements for MIR548AM Gene

Enhancers for MIR548AM Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XG016628 0.7 ENCODE 0.7 -2.3 -2328 1.4 CTCF NR4A1 TAL1 TEAD4 ZNF592 TCF12 ARID1B ZNF316 HNF1A HMBOX1 S100G MIR548AM
GH0XG016603 1.2 Ensembl ENCODE 0.3 +22.3 22330 2.6 ELF3 ZFP64 TCF12 ZNF121 ZNF138 GATA2 ZNF354C ZNF202 ZNF654 ZNF680 TXLNG S100G MIR548AM GC0XP016584
GH0XG016585 1.1 Ensembl ENCODE 0.3 +40.8 40762 1.5 ELF3 TCF12 ZNF766 GATA2 CAVIN1 CEBPB ZNF592 MEF2D CREB3 NFIC S100G GC0XP016584 MIR548AM
GH0XG016633 0.8 ENCODE 0.4 -6.8 -6837 1.4 HDAC1 ESRRA ETV1 ZNF121 ZNF316 GATA2 NCOR1 NFE2 FOS MAFK MIR548AM S100G
GH0XG016643 0.8 Ensembl ENCODE 0.4 -16.2 -16238 0.3 JUND JUN CEBPB CREB1 ATF2 S100G MIR548AM
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548AM on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548AM Gene

Chromosome:
X
Start:
16,627,012 bp from pter
End:
16,627,085 bp from pter
Size:
74 bases
Orientation:
Minus strand

Genomic View for MIR548AM Gene

Genes around MIR548AM on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AM Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AM Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AM Gene

Proteins for MIR548AM Gene

Post-translational modifications for MIR548AM Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AM Gene

Domains & Families for MIR548AM Gene

Gene Families for MIR548AM Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AM: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AM Gene

Function for MIR548AM Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AM Gene

Localization for MIR548AM Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AM Gene

Pathways & Interactions for MIR548AM Gene

SuperPathways for MIR548AM Gene

No Data Available

Interacting Proteins for MIR548AM Gene

Gene Ontology (GO) - Biological Process for MIR548AM Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AM Gene

Drugs & Compounds for MIR548AM Gene

No Compound Related Data Available

Transcripts for MIR548AM Gene

mRNA/cDNA for MIR548AM Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AM Gene

No ASD Table

Relevant External Links for MIR548AM Gene

GeneLoc Exon Structure for
MIR548AM
ECgene alternative splicing isoforms for
MIR548AM

Expression for MIR548AM Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AM Gene:

MIR548AM
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AM Gene

Orthologs for MIR548AM Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AM Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 97 (a)
OneToOne
Species where no ortholog for MIR548AM was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AM Gene

ENSEMBL:
Gene Tree for MIR548AM (if available)
TreeFam:
Gene Tree for MIR548AM (if available)

Paralogs for MIR548AM Gene

No data available for Paralogs for MIR548AM Gene

Variants for MIR548AM Gene

Sequence variations from dbSNP and Humsavar for MIR548AM Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000584019 -- 16,627,808(+) TCCAC(C/T)CACCA intron-variant, upstream-variant-2KB
rs1000737428 -- 16,627,362(+) CGCTT(G/T)CAGAG intron-variant, upstream-variant-2KB
rs1001037975 -- 16,628,480(+) CCTGA(C/T)TCAGT intron-variant, upstream-variant-2KB
rs1006719906 -- 16,626,888(+) CGCTC(C/T)CCTGG intron-variant, downstream-variant-500B
rs1012408735 -- 16,628,545(+) AGTTT(-/TA)GTAGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AM Gene

Variant ID Type Subtype PubMed ID
nsv6815 CNV insertion 18451855

Relevant External Links for MIR548AM Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AM

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AM Gene

Disorders for MIR548AM Gene

Relevant External Links for MIR548AM

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548AM

No disorders were found for MIR548AM Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AM Gene

Publications for MIR548AM Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548AM Gene

Sources for MIR548AM Gene

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