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Aliases for MIR548AJ2 Gene

Subcategory (RNA class) for MIR548AJ2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AJ2 Gene

  • MicroRNA 548aj-2 2 3 5
  • Hsa-Mir-548aj-2 3

External Ids for MIR548AJ2 Gene

Previous GeneCards Identifiers for MIR548AJ2 Gene

  • GC0XU901747
  • GC0XM037885

Summaries for MIR548AJ2 Gene

Entrez Gene Summary for MIR548AJ2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AJ2 Gene

MIR548AJ2 (MicroRNA 548aj-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AJ2 Gene

Genomics for MIR548AJ2 Gene

Regulatory Elements for MIR548AJ2 Gene

Enhancers for MIR548AJ2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF038005 0.2 ENCODE 0.3 +17.6 17581 1.3 TAL1 DPF2 ZNF217 CTBP1 GATA3 NCOR1 KLF9 SETDB1 TRIM28 SYTL5 ENSG00000229674 MIR548AJ2
GH0XF038051 0.5 ENCODE 0.3 -28.3 -28331 1.1 JUN SIN3A ZNF2 ZKSCAN1 SCRT2 FOS ZNF600 MAFK ZBTB20 NFE2L2 SYTL5 GC0XM038060 MIR548AJ2
GH0XF037994 0.7 ENCODE 0.3 +29.6 29564 0.2 RFX1 ENSG00000229674 MIR548AJ2
GH0XF038061 0.2 ENCODE 0.3 -37.5 -37537 0.2 PKNOX1 FEZF1 ZNF2 GLIS2 KLF7 FOS SP3 TSHZ1 ZNF488 ZNF518A MOB1AP2 LOC442445 GC0XM038060 MIR548AJ2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548AJ2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548AJ2 Gene

Chromosome:
X
Start:
38,023,895 bp from pter
End:
38,023,986 bp from pter
Size:
92 bases
Orientation:
Minus strand

Genomic View for MIR548AJ2 Gene

Genes around MIR548AJ2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AJ2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AJ2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AJ2 Gene

Proteins for MIR548AJ2 Gene

Post-translational modifications for MIR548AJ2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AJ2 Gene

Domains & Families for MIR548AJ2 Gene

Gene Families for MIR548AJ2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AJ2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AJ2 Gene

Function for MIR548AJ2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AJ2 Gene

Localization for MIR548AJ2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AJ2 Gene

Pathways & Interactions for MIR548AJ2 Gene

SuperPathways for MIR548AJ2 Gene

No Data Available

Interacting Proteins for MIR548AJ2 Gene

Gene Ontology (GO) - Biological Process for MIR548AJ2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AJ2 Gene

Transcripts for MIR548AJ2 Gene

mRNA/cDNA for MIR548AJ2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AJ2 Gene

No ASD Table

Relevant External Links for MIR548AJ2 Gene

GeneLoc Exon Structure for
MIR548AJ2
ECgene alternative splicing isoforms for
MIR548AJ2

Expression for MIR548AJ2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AJ2 Gene:

MIR548AJ2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548AJ2 Gene

Orthologs for MIR548AJ2 Gene

Evolution for MIR548AJ2 Gene

ENSEMBL:
Gene Tree for MIR548AJ2 (if available)
TreeFam:
Gene Tree for MIR548AJ2 (if available)

No data available for Orthologs for MIR548AJ2 Gene

Paralogs for MIR548AJ2 Gene

No data available for Paralogs for MIR548AJ2 Gene

Variants for MIR548AJ2 Gene

Sequence variations from dbSNP and Humsavar for MIR548AJ2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs111409449 -- 38,024,733(+) AATAA(C/G)TGTTA intron-variant, upstream-variant-2KB
rs112023524 -- 38,025,611(+) TCTAT(A/G)TTTAA intron-variant, upstream-variant-2KB
rs113330267 -- 38,023,912(+) TGGTG(C/T)AAAAG intron-variant, nc-transcript-variant
rs113452793 -- 38,024,340(+) ACGTG(A/C)CTTTG intron-variant, upstream-variant-2KB
rs113826318 -- 38,023,660(+) TTTTA(A/G)AATTG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR548AJ2 Gene

Variant ID Type Subtype PubMed ID
dgv2277e212 CNV loss 25503493
esv2752323 CNV gain 17911159
nsv518029 CNV gain 19592680
nsv519012 CNV gain 19592680

Relevant External Links for MIR548AJ2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AJ2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AJ2 Gene

Disorders for MIR548AJ2 Gene

Relevant External Links for MIR548AJ2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548AJ2

No disorders were found for MIR548AJ2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AJ2 Gene

Publications for MIR548AJ2 Gene

  1. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548AJ2 Gene

Sources for MIR548AJ2 Gene

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