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Aliases for MIR548AJ1 Gene

Subcategory (RNA class) for MIR548AJ1 Gene


Quality Score for this RNA gene is


Aliases for MIR548AJ1 Gene

  • MicroRNA 548aj-1 2 3 5
  • Hsa-Mir-548aj-1 3

External Ids for MIR548AJ1 Gene

Previous GeneCards Identifiers for MIR548AJ1 Gene

  • GC06U902229
  • GC06M132437

Summaries for MIR548AJ1 Gene

Entrez Gene Summary for MIR548AJ1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AJ1 Gene

MIR548AJ1 (MicroRNA 548aj-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AJ1 Gene

Genomics for MIR548AJ1 Gene

Regulatory Elements for MIR548AJ1 Gene

Enhancers for MIR548AJ1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F132115 1.1 Ensembl ENCODE 0.8 -1.0 -1006 1.1 PKNOX1 ZNF558 MIR548AJ1 ENSG00000280155
GH06F132121 0.5 ENCODE 0.4 -7.4 -7351 2.6 SOX13 INSM2 FEZF1 ZIC2 RARA SMC3 FOS NR2F6 ZNF652 MAFK ENSG00000280155 MIR548AJ1
GH06F132082 1 FANTOM5 Ensembl ENCODE 0.3 +29.9 29906 4.9 PKNOX1 ZNF146 USF1 JUN BMI1 FOS CREM MAFK MTA2 ZBED1 LINC01013 AKAP7 ENSG00000236166 MIR548AJ1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548AJ1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548AJ1 Gene

132,115,192 bp from pter
132,115,263 bp from pter
72 bases
Minus strand

Genomic View for MIR548AJ1 Gene

Genes around MIR548AJ1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AJ1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AJ1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AJ1 Gene

Proteins for MIR548AJ1 Gene

Post-translational modifications for MIR548AJ1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AJ1 Gene

Domains & Families for MIR548AJ1 Gene

Gene Families for MIR548AJ1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AJ1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AJ1 Gene

Function for MIR548AJ1 Gene

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AJ1 Gene

Localization for MIR548AJ1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AJ1 Gene

Pathways & Interactions for MIR548AJ1 Gene

SuperPathways for MIR548AJ1 Gene

No Data Available

Interacting Proteins for MIR548AJ1 Gene

Gene Ontology (GO) - Biological Process for MIR548AJ1 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AJ1 Gene

Transcripts for MIR548AJ1 Gene

mRNA/cDNA for MIR548AJ1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AJ1 Gene

No ASD Table

Relevant External Links for MIR548AJ1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AJ1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AJ1 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548AJ1 Gene

Orthologs for MIR548AJ1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AJ1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 35
  • 100 (a)
Species where no ortholog for MIR548AJ1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AJ1 Gene

Gene Tree for MIR548AJ1 (if available)
Gene Tree for MIR548AJ1 (if available)

Paralogs for MIR548AJ1 Gene

No data available for Paralogs for MIR548AJ1 Gene

Variants for MIR548AJ1 Gene

Sequence variations from dbSNP and Humsavar for MIR548AJ1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs113096789 -- 132,116,694(+) GACTA(C/T)TAAAG upstream-variant-2KB
rs115235622 -- 132,115,492(+) TCGGG(A/G)CGAAG upstream-variant-2KB
rs115523330 -- 132,116,195(+) CGTAA(C/T)AGTCC upstream-variant-2KB
rs116492451 -- 132,116,446(+) TGAGA(C/T)ATTCT upstream-variant-2KB
rs12110962 -- 132,116,674(+) CACAG(A/G)AAATA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AJ1 Gene

Variant ID Type Subtype PubMed ID
esv2762616 CNV gain 21179565
esv3610830 CNV gain 21293372

Relevant External Links for MIR548AJ1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AJ1 Gene

Disorders for MIR548AJ1 Gene

Relevant External Links for MIR548AJ1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548AJ1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AJ1 Gene

Publications for MIR548AJ1 Gene

  1. Quantitative Lys-I/-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. (PMID: 25147182) Thompson J.W. … Luchansky S.J. (J. Biol. Chem. 2014) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548AJ1 Gene

Sources for MIR548AJ1 Gene

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