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Aliases for MIR548AI Gene

Subcategory (RNA class) for MIR548AI Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AI Gene

  • MicroRNA 548ai 2 3 5
  • Hsa-Mir-548ai 3

External Ids for MIR548AI Gene

Previous GeneCards Identifiers for MIR548AI Gene

  • GC06U902223
  • GC06P099573

Summaries for MIR548AI Gene

Entrez Gene Summary for MIR548AI Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AI Gene

MIR548AI (MicroRNA 548ai) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AI Gene

Genomics for MIR548AI Gene

Genomic Location for MIR548AI Gene

Chromosome:
6
Start:
99,124,609 bp from pter
End:
99,124,696 bp from pter
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR548AI Gene

Genes around MIR548AI on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AI Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AI Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AI Gene

No data available for Regulatory Elements for MIR548AI Gene

Proteins for MIR548AI Gene

Post-translational modifications for MIR548AI Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AI Gene

Domains & Families for MIR548AI Gene

Gene Families for MIR548AI Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AI: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AI Gene

Function for MIR548AI Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AI Gene

Localization for MIR548AI Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AI Gene

Pathways & Interactions for MIR548AI Gene

SuperPathways for MIR548AI Gene

No Data Available

Interacting Proteins for MIR548AI Gene

Gene Ontology (GO) - Biological Process for MIR548AI Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AI Gene

Drugs & Compounds for MIR548AI Gene

No Compound Related Data Available

Transcripts for MIR548AI Gene

mRNA/cDNA for MIR548AI Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AI Gene

No ASD Table

Relevant External Links for MIR548AI Gene

GeneLoc Exon Structure for
MIR548AI
ECgene alternative splicing isoforms for
MIR548AI

Expression for MIR548AI Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AI Gene:

MIR548AI
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548AI Gene

Orthologs for MIR548AI Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AI Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 99 (a)
OneToOne
Species where no ortholog for MIR548AI was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AI Gene

ENSEMBL:
Gene Tree for MIR548AI (if available)
TreeFam:
Gene Tree for MIR548AI (if available)

Paralogs for MIR548AI Gene

No data available for Paralogs for MIR548AI Gene

Variants for MIR548AI Gene

Sequence variations from dbSNP and Humsavar for MIR548AI Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs9493494 -- 99,124,821(+) gccaa(A/G)aacac downstream-variant-500B
rs71021708 -- 99,123,014(-) AGTAA(-/ACAC)ACACA upstream-variant-2KB
rs11301304 -- 99,124,015(+) AGCAG(-/C)CCCCC upstream-variant-2KB
rs11755926 -- 99,124,775(+) CCATC(A/G)TTCAC downstream-variant-500B
rs72943260 -- 99,122,785(+) CCAAG(A/G)CTACC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AI Gene

Variant ID Type Subtype PubMed ID
dgv368e201 CNV deletion 23290073
dgv369e201 CNV deletion 23290073
dgv475n67 CNV gain 20364138
esv2335999 CNV deletion 18987734
esv23394 CNV gain 19812545
esv2574030 CNV deletion 19546169
esv2658882 CNV deletion 23128226
esv2714465 CNV deletion 23290073
esv2714466 CNV deletion 23290073
esv2714469 CNV deletion 23290073
esv2714470 CNV deletion 23290073
esv2714471 CNV deletion 23290073
esv2714475 CNV deletion 23290073
esv2743075 CNV deletion 23290073
esv29244 CNV gain+loss 19812545
esv3445240 CNV duplication 20981092
esv3582198 CNV loss 25503493
esv3582199 CNV loss 25503493
esv988568 CNV deletion 20482838
esv994746 CNV deletion 20482838
nsv1029536 CNV loss 25217958
nsv1056530 CNV gain 25217958
nsv1066288 CNV gain 25217958
nsv1109011 CNV deletion 24896259
nsv1118352 CNV deletion 24896259
nsv507816 OTHER sequence alteration 20534489
nsv512438 CNV loss 21212237
nsv604253 CNV gain 21841781
nsv821596 CNV deletion 20802225
nsv833224 CNV loss 17160897
nsv833225 CNV gain 17160897
nsv952675 CNV deletion 24416366
nsv958047 CNV deletion 24416366

Relevant External Links for MIR548AI Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AI

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AI Gene

Disorders for MIR548AI Gene

Relevant External Links for MIR548AI

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548AI

No disorders were found for MIR548AI Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AI Gene

Publications for MIR548AI Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 65
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 65

Products for MIR548AI Gene

Sources for MIR548AI Gene

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