Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR548AG2 Gene

Subcategory (RNA class) for MIR548AG2 Gene


Quality Score for this RNA gene is


Aliases for MIR548AG2 Gene

  • MicroRNA 548ag-2 2 3 5
  • Hsa-Mir-548ag-2 3

External Ids for MIR548AG2 Gene

Previous GeneCards Identifiers for MIR548AG2 Gene

  • GC20U900688
  • GC20P059140

Summaries for MIR548AG2 Gene

Entrez Gene Summary for MIR548AG2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AG2 Gene

MIR548AG2 (MicroRNA 548ag-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AG2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AG2 Gene

Genomics for MIR548AG2 Gene

Regulatory Elements for MIR548AG2 Gene

Enhancers for MIR548AG2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20H060511 0.8 Ensembl ENCODE 0.2 -52.0 -51959 1.6 JUND STAT3 FOS CUX1 MIR4533 MIR548AG2
GH20H060564 0.2 ENCODE 0.7 +0.8 786 1.6 MIR548AG2 GC20M060541
GH20H060533 0.4 FANTOM5 0.3 -31.2 -31235 0 MAFK MIR548AG2 MIR4533
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548AG2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AG2 Gene

Genomic Locations for MIR548AG2 Gene
64 bases
Plus strand

Genomic View for MIR548AG2 Gene

Genes around MIR548AG2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AG2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AG2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AG2 Gene

Proteins for MIR548AG2 Gene

Post-translational modifications for MIR548AG2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AG2 Gene

Domains & Families for MIR548AG2 Gene

Gene Families for MIR548AG2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AG2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AG2 Gene

Function for MIR548AG2 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AG2 Gene

Localization for MIR548AG2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AG2 Gene

Pathways & Interactions for MIR548AG2 Gene

SuperPathways for MIR548AG2 Gene

No Data Available

Interacting Proteins for MIR548AG2 Gene

Gene Ontology (GO) - Biological Process for MIR548AG2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AG2 Gene

Drugs & Compounds for MIR548AG2 Gene

No Compound Related Data Available

Transcripts for MIR548AG2 Gene

mRNA/cDNA for MIR548AG2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AG2 Gene

No ASD Table

Relevant External Links for MIR548AG2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AG2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AG2 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AG2 Gene

Orthologs for MIR548AG2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AG2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 100 (a)
Species where no ortholog for MIR548AG2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AG2 Gene

Gene Tree for MIR548AG2 (if available)
Gene Tree for MIR548AG2 (if available)

Paralogs for MIR548AG2 Gene

No data available for Paralogs for MIR548AG2 Gene

Variants for MIR548AG2 Gene

Sequence variations from dbSNP and Humsavar for MIR548AG2 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1000516903 -- 60,564,793(+) TTTCT(A/G)TGGAT downstream-variant-500B
rs1000921430 -- 60,564,281(+) TACTA(C/T)AGAAA upstream-variant-2KB
rs1001379752 -- 60,563,961(+) GTTTT(A/G)AACAC upstream-variant-2KB
rs1004507779 -- 60,563,285(+) GAAAA(A/T)TTAGG upstream-variant-2KB
rs1005416219 -- 60,562,623(+) GAGAG(C/G)CGTTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AG2 Gene

Variant ID Type Subtype PubMed ID
nsv834022 CNV gain 17160897
esv3893353 CNV gain 25118596

Relevant External Links for MIR548AG2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AG2 Gene

Disorders for MIR548AG2 Gene

Relevant External Links for MIR548AG2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548AG2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AG2 Gene

Publications for MIR548AG2 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR548AG2 Gene

Sources for MIR548AG2 Gene

Loading form....