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Aliases for MIR548AE2 Gene

Subcategory (RNA class) for MIR548AE2 Gene


Quality Score for this RNA gene is


Aliases for MIR548AE2 Gene

  • MicroRNA 548ae-2 2 3 5
  • Hsa-Mir-548ae-2 3

External Ids for MIR548AE2 Gene

Previous GeneCards Identifiers for MIR548AE2 Gene

  • GC05U901575
  • GC05M057826

Summaries for MIR548AE2 Gene

Entrez Gene Summary for MIR548AE2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AE2 Gene

MIR548AE2 (MicroRNA 548ae-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR548AE2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AE2 Gene

Genomics for MIR548AE2 Gene

Regulatory Elements for MIR548AE2 Gene

Enhancers for MIR548AE2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H058543 0.8 FANTOM5 Ensembl 0.4 -14.3 -14293 1.6 NFE2 MYC GAPT MIR548AE2 GC05P058555
GH05H058545 0.5 Ensembl 0.4 -16.1 -16134 0.7 JUND ATF3 NR2F1 NR2F2 GAPT GC05P058555 MIR548AE2
GH05H058505 0.4 Ensembl 0.3 +23.9 23909 0.8 SPI1 GAPT LINC02108 ENSG00000271257 MIR548AE2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548AE2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548AE2 Gene

Genomic Locations for MIR548AE2 Gene
67 bases
Minus strand

Genomic View for MIR548AE2 Gene

Genes around MIR548AE2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AE2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AE2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AE2 Gene

ORGUL Member Location for MIR548AE2 Gene

ORGUL Member Location for MIR548AE2 gene

Proteins for MIR548AE2 Gene

Post-translational modifications for MIR548AE2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AE2 Gene

Domains & Families for MIR548AE2 Gene

Gene Families for MIR548AE2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AE2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AE2 Gene

Function for MIR548AE2 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AE2 Gene

Localization for MIR548AE2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548AE2 Gene

Pathways & Interactions for MIR548AE2 Gene

SuperPathways for MIR548AE2 Gene

No Data Available

Interacting Proteins for MIR548AE2 Gene

Gene Ontology (GO) - Biological Process for MIR548AE2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AE2 Gene

Drugs & Compounds for MIR548AE2 Gene

No Compound Related Data Available

Transcripts for MIR548AE2 Gene

mRNA/cDNA for MIR548AE2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AE2 Gene

No ASD Table

Relevant External Links for MIR548AE2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AE2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AE2 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548AE2 Gene

Orthologs for MIR548AE2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AE2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 61 (a)
Species where no ortholog for MIR548AE2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AE2 Gene

Gene Tree for MIR548AE2 (if available)
Gene Tree for MIR548AE2 (if available)

Paralogs for MIR548AE2 Gene

No data available for Paralogs for MIR548AE2 Gene

Variants for MIR548AE2 Gene

Sequence variations from dbSNP and Humsavar for MIR548AE2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000229877 -- 58,531,432(+) CCTTC(A/C)CCTTC upstream-variant-2KB
rs1001233510 -- 58,530,149(+) GCATG(C/G/T)TTTAA upstream-variant-2KB
rs1001737887 -- 58,530,724(+) ATACA(C/T)ATTGA upstream-variant-2KB
rs1002862368 -- 58,531,901(+) CTTCA(C/T)GCCCT upstream-variant-2KB
rs1004315637 -- 58,531,529(+) TTAAA(C/T)CTCTT upstream-variant-2KB

Relevant External Links for MIR548AE2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548AE2 Gene

Disorders for MIR548AE2 Gene

Relevant External Links for MIR548AE2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548AE2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AE2 Gene

Publications for MIR548AE2 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR548AE2 Gene

Sources for MIR548AE2 Gene

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