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Aliases for MIR548AE2 Gene

Subcategory (RNA class) for MIR548AE2 Gene


Quality Score for this RNA gene is


Aliases for MIR548AE2 Gene

  • MicroRNA 548ae-2 2 3
  • Hsa-Mir-548ae-2 3

External Ids for MIR548AE2 Gene

Previous GeneCards Identifiers for MIR548AE2 Gene

  • GC05U901575
  • GC05M057826

Summaries for MIR548AE2 Gene

Entrez Gene Summary for MIR548AE2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AE2 Gene

MIR548AE2 (MicroRNA 548ae-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AE2 Gene

Genomics for MIR548AE2 Gene

Genomic Location for MIR548AE2 Gene

58,530,043 bp from pter
58,530,109 bp from pter
67 bases
Minus strand

Genomic View for MIR548AE2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548AE2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AE2 Gene

ORGUL Member Location for MIR548AE2 Gene

ORGUL Member Location for MIR548AE2 gene

No data available for Regulatory Elements for MIR548AE2 Gene

Proteins for MIR548AE2 Gene

Post-translational modifications for MIR548AE2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AE2 Gene

Domains for MIR548AE2 Gene

Gene Families for MIR548AE2 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AE2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AE2 Gene

Function for MIR548AE2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548AE2 Gene

Localization for MIR548AE2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AE2 Gene

Pathways for MIR548AE2 Gene

SuperPathways for MIR548AE2 Gene

No Data Available

Interacting Proteins for MIR548AE2 Gene

Gene Ontology (GO) - Biological Process for MIR548AE2 Gene


No data available for Pathways by source for MIR548AE2 Gene

Transcripts for MIR548AE2 Gene

mRNA/cDNA for MIR548AE2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AE2 Gene

No ASD Table

Relevant External Links for MIR548AE2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AE2 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR548AE2 Gene

Orthologs for MIR548AE2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AE2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 61 (a)
Species with no ortholog for MIR548AE2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AE2 Gene

Gene Tree for MIR548AE2 (if available)
Gene Tree for MIR548AE2 (if available)

Paralogs for MIR548AE2 Gene

No data available for Paralogs for MIR548AE2 Gene

Variants for MIR548AE2 Gene

Sequence variations from dbSNP and Humsavar for MIR548AE2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs10051665 -- 58,529,775(+) agtca(C/T)ttttt downstream-variant-500B
rs10057243 -- 58,530,363(+) tatac(A/G)tttta upstream-variant-2KB
rs10461441 -- 58,530,093(+) AAACC(A/G)CAATT nc-transcript-variant
rs10940616 -- 58,531,491(+) gctat(A/G)tttac upstream-variant-2KB
rs11740428 -- 58,531,931(+) aactt(C/G/T)agagt upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AE2 Gene

Variant ID Type Subtype PubMed ID
esv2595682 CNV Insertion 19546169
esv1677967 CNV Insertion 17803354
nsv833219 CNV Gain 17160897
dgv888e1 CNV Complex 17122850
esv26254 CNV Loss 19812545

Relevant External Links for MIR548AE2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR548AE2 Gene

Disorders for MIR548AE2 Gene

No disorders were found for MIR548AE2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR548AE2 Gene

Publications for MIR548AE2 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR548AE2 Gene

Sources for MIR548AE2 Gene

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