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Aliases for MIR548AE1 Gene

Subcategory (RNA class) for MIR548AE1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AE1 Gene

  • MicroRNA 548ae-1 2 3 5
  • Hsa-Mir-548ae-1 3

External Ids for MIR548AE1 Gene

Previous GeneCards Identifiers for MIR548AE1 Gene

  • GC02U902439
  • GC02P185244

Summaries for MIR548AE1 Gene

Entrez Gene Summary for MIR548AE1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AE1 Gene

MIR548AE1 (MicroRNA 548ae-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AE1 Gene

Genomics for MIR548AE1 Gene

Genomic Location for MIR548AE1 Gene

Chromosome:
2
Start:
184,378,975 bp from pter
End:
184,379,044 bp from pter
Size:
70 bases
Orientation:
Plus strand

Genomic View for MIR548AE1 Gene

Genes around MIR548AE1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AE1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AE1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AE1 Gene

No data available for Regulatory Elements for MIR548AE1 Gene

Proteins for MIR548AE1 Gene

Post-translational modifications for MIR548AE1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AE1 Gene

Domains & Families for MIR548AE1 Gene

Gene Families for MIR548AE1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AE1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AE1 Gene

Function for MIR548AE1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AE1 Gene

Localization for MIR548AE1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AE1 Gene

Pathways & Interactions for MIR548AE1 Gene

SuperPathways for MIR548AE1 Gene

No Data Available

Interacting Proteins for MIR548AE1 Gene

Gene Ontology (GO) - Biological Process for MIR548AE1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AE1 Gene

Drugs & Compounds for MIR548AE1 Gene

No Compound Related Data Available

Transcripts for MIR548AE1 Gene

mRNA/cDNA for MIR548AE1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AE1 Gene

No ASD Table

Relevant External Links for MIR548AE1 Gene

GeneLoc Exon Structure for
MIR548AE1
ECgene alternative splicing isoforms for
MIR548AE1

Expression for MIR548AE1 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR548AE1 Gene

Orthologs for MIR548AE1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AE1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR548AE1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AE1 Gene

ENSEMBL:
Gene Tree for MIR548AE1 (if available)
TreeFam:
Gene Tree for MIR548AE1 (if available)

Paralogs for MIR548AE1 Gene

No data available for Paralogs for MIR548AE1 Gene

Variants for MIR548AE1 Gene

Relevant External Links for MIR548AE1 Gene

HapMap Linkage Disequilibrium report
MIR548AE1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548AE1 Gene

Disorders for MIR548AE1 Gene

Relevant External Links for MIR548AE1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548AE1

No disorders were found for MIR548AE1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AE1 Gene

Publications for MIR548AE1 Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 67
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR548AE1 Gene

Sources for MIR548AE1 Gene

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