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Aliases for MIR548AD Gene

Subcategory (RNA class) for MIR548AD Gene


Quality Score for this RNA gene is


Aliases for MIR548AD Gene

  • MicroRNA 548ad 2 3 5
  • Hsa-Mir-548ad 3

External Ids for MIR548AD Gene

Previous GeneCards Identifiers for MIR548AD Gene

  • GC02U902438
  • GC02P035702
  • GC02P035706
  • GC02P035709
  • GC02P035473
  • GC02P035475
  • GC02P035477
  • GC02P035479

Summaries for MIR548AD Gene

Entrez Gene Summary for MIR548AD Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AD Gene

MIR548AD (MicroRNA 548ad) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AD Gene

Genomics for MIR548AD Gene

Regulatory Elements for MIR548AD Gene

Enhancers for MIR548AD Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F035461 0.7 ENCODE 0.4 -8.4 -8353 2.8 GATA3 MNT ZBTB40 MAFK EZH2 MIR548AD GC02P035437
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548AD on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548AD Gene

35,471,405 bp from pter
35,471,486 bp from pter
82 bases
Plus strand

Genomic View for MIR548AD Gene

Genes around MIR548AD on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AD Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AD Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AD Gene

Proteins for MIR548AD Gene

Post-translational modifications for MIR548AD Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AD Gene

Domains & Families for MIR548AD Gene

Gene Families for MIR548AD Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AD: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AD Gene

Function for MIR548AD Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AD Gene

Localization for MIR548AD Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AD Gene

Pathways & Interactions for MIR548AD Gene

SuperPathways for MIR548AD Gene

No Data Available

Interacting Proteins for MIR548AD Gene

Gene Ontology (GO) - Biological Process for MIR548AD Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548AD Gene

Transcripts for MIR548AD Gene

mRNA/cDNA for MIR548AD Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AD Gene

No ASD Table

Relevant External Links for MIR548AD Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AD Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR548AD Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AD Gene:

genes like me logo Genes that share expression patterns with MIR548AD: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548AD Gene

Orthologs for MIR548AD Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AD Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 35
  • 98 (a)
Species where no ortholog for MIR548AD was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AD Gene

Gene Tree for MIR548AD (if available)
Gene Tree for MIR548AD (if available)

Paralogs for MIR548AD Gene

No data available for Paralogs for MIR548AD Gene

Variants for MIR548AD Gene

Sequence variations from dbSNP and Humsavar for MIR548AD Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs111886240 -- 35,470,243(+) ATTAT(A/T)TTTTA upstream-variant-2KB
rs113759269 -- 35,470,382(+) AAAAG(G/T)TTATT upstream-variant-2KB
rs115818870 -- 35,471,466(+) CAATG(A/G)CTTTT nc-transcript-variant
rs115876369 -- 35,470,487(+) AAATT(C/T)GTAAT upstream-variant-2KB
rs11692039 -- 35,469,797(+) AGATA(A/C)CAAGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AD Gene

Variant ID Type Subtype PubMed ID
esv3575225 CNV gain 25503493
nsv1008651 CNV loss 25217958
nsv1010722 CNV gain 25217958
nsv1014577 CNV loss 25217958
nsv519522 CNV gain 19592680
nsv581402 CNV loss 21841781

Relevant External Links for MIR548AD Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AD Gene

Disorders for MIR548AD Gene

Relevant External Links for MIR548AD

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548AD Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AD Gene

Publications for MIR548AD Gene

  1. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen T.B. … Bramsen J.B. (RNA Biol 2011) 3 64
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548AD Gene

Sources for MIR548AD Gene

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