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Aliases for MIR548AC Gene

Subcategory (RNA class) for MIR548AC Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548AC Gene

  • MicroRNA 548ac 2 3
  • Hsa-Mir-548ac 3

External Ids for MIR548AC Gene

Summaries for MIR548AC Gene

Entrez Gene Summary for MIR548AC Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AC Gene

MIR548AC (MicroRNA 548ac) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AC Gene

Genomics for MIR548AC Gene

Genomic Location for MIR548AC Gene

Start:
116,560,024 bp from pter
End:
116,560,111 bp from pter
Size:
88 bases
Orientation:
Minus strand

Genomic View for MIR548AC Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548AC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AC Gene

ORGUL Member Location for MIR548AC Gene

ORGUL Member Location for MIR548AC gene

No data available for Regulatory Elements for MIR548AC Gene

Proteins for MIR548AC Gene

Post-translational modifications for MIR548AC Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AC Gene

Domains for MIR548AC Gene

Gene Families for MIR548AC Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR548AC: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR548AC Gene

Function for MIR548AC Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548AC Gene

Localization for MIR548AC Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR548AC Gene

Pathways for MIR548AC Gene

SuperPathways for MIR548AC Gene

No Data Available

Interacting Proteins for MIR548AC Gene

Gene Ontology (GO) - Biological Process for MIR548AC Gene

None

No data available for Pathways by source for MIR548AC Gene

Transcripts for MIR548AC Gene

mRNA/cDNA for MIR548AC Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AC Gene

No ASD Table

Relevant External Links for MIR548AC Gene

GeneLoc Exon Structure for
MIR548AC
ECgene alternative splicing isoforms for
MIR548AC

Expression for MIR548AC Gene

mRNA expression in normal human tissues for MIR548AC Gene

genes like me logo Genes that share expressions with MIR548AC: view

Orthologs for MIR548AC Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 98 (a)
OneToOne
Species with no ortholog for MIR548AC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AC Gene

ENSEMBL:
Gene Tree for MIR548AC (if available)
TreeFam:
Gene Tree for MIR548AC (if available)

Paralogs for MIR548AC Gene

No data available for Paralogs for MIR548AC Gene

Variants for MIR548AC Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548AC Gene

Variant ID Type Subtype PubMed ID
nsv876624 CNV Loss 21882294
nsv876625 CNV Gain 21882294
nsv236860 CNV Loss 16902084
esv25457 CNV Loss 19812545
esv2669216 CNV Deletion 23128226
esv268283 CNV Insertion 20981092
nsv526739 CNV Loss 19592680
esv2725037 CNV Deletion 23290073
esv2674431 CNV Deletion 23128226
nsv460479 CNV Gain 19166990

Relevant External Links for MIR548AC Gene

HapMap Linkage Disequilibrium report
MIR548AC

No data available for Sequence variations from dbSNP and Humsavar for MIR548AC Gene

Disorders for MIR548AC Gene

No disorders were found for MIR548AC Gene.

No data available for UniProtKB/Swiss-Prot for MIR548AC Gene

Publications for MIR548AC Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. (PMID: 19525953) De Jager P.L. … Oksenberg J.R. (Nat. Genet. 2009) 3
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3
  4. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. (PMID: 22190364) Patsopoulos N.A. … de Bakker P.I. (Ann. Neurol. 2011) 3

Products for MIR548AC Gene

Sources for MIR548AC Gene

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