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Aliases for MIR548AC Gene

Subcategory (RNA class) for MIR548AC Gene


Quality Score for this RNA gene is


Aliases for MIR548AC Gene

  • MicroRNA 548ac 2 3
  • Hsa-Mir-548ac 3

External Ids for MIR548AC Gene

Previous GeneCards Identifiers for MIR548AC Gene

  • GC01U903272
  • GC01M117104

Summaries for MIR548AC Gene

Entrez Gene Summary for MIR548AC Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AC Gene

MIR548AC (MicroRNA 548ac) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AC Gene

Genomics for MIR548AC Gene

Genomic Location for MIR548AC Gene

116,560,024 bp from pter
116,560,111 bp from pter
88 bases
Minus strand

Genomic View for MIR548AC Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548AC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AC Gene

ORGUL Member Location for MIR548AC Gene

ORGUL Member Location for MIR548AC gene

No data available for Regulatory Elements for MIR548AC Gene

Proteins for MIR548AC Gene

Post-translational modifications for MIR548AC Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AC Gene

Domains for MIR548AC Gene

Gene Families for MIR548AC Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AC: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AC Gene

Function for MIR548AC Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548AC Gene

Localization for MIR548AC Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AC Gene

Pathways for MIR548AC Gene

SuperPathways for MIR548AC Gene

No Data Available

Interacting Proteins for MIR548AC Gene

Gene Ontology (GO) - Biological Process for MIR548AC Gene


No data available for Pathways by source for MIR548AC Gene

Transcripts for MIR548AC Gene

mRNA/cDNA for MIR548AC Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AC Gene

No ASD Table

Relevant External Links for MIR548AC Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548AC Gene

mRNA expression in normal human tissues for MIR548AC Gene

genes like me logo Genes that share expressions with MIR548AC: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR548AC Gene

Orthologs for MIR548AC Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AC Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
Species with no ortholog for MIR548AC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AC Gene

Gene Tree for MIR548AC (if available)
Gene Tree for MIR548AC (if available)

Paralogs for MIR548AC Gene

No data available for Paralogs for MIR548AC Gene

Variants for MIR548AC Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR548AC Gene

Variant ID Type Subtype PubMed ID
nsv876624 CNV Loss 21882294
nsv876625 CNV Gain 21882294
nsv236860 CNV Loss 16902084
esv25457 CNV Loss 19812545
esv2669216 CNV Deletion 23128226
esv268283 CNV Insertion 20981092
nsv526739 CNV Loss 19592680
esv2725037 CNV Deletion 23290073
esv2674431 CNV Deletion 23128226
nsv460479 CNV Gain 19166990

Relevant External Links for MIR548AC Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR548AC Gene

Disorders for MIR548AC Gene

No disorders were found for MIR548AC Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR548AC Gene

Publications for MIR548AC Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. (PMID: 19525953) De Jager P.L. … Oksenberg J.R. (Nat. Genet. 2009) 3
  3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3
  4. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. (PMID: 22190364) Patsopoulos N.A. … de Bakker P.I. (Ann. Neurol. 2011) 3

Products for MIR548AC Gene

Sources for MIR548AC Gene

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