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Aliases for MIR548AB Gene

Subcategory (RNA class) for MIR548AB Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR548AB Gene

  • MicroRNA 548ab 2 3
  • Hsa-Mir-548ab 3

External Ids for MIR548AB Gene

Previous GeneCards Identifiers for MIR548AB Gene

  • GC03U901785
  • GC03M103243

Summaries for MIR548AB Gene

Entrez Gene Summary for MIR548AB Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AB Gene

MIR548AB (MicroRNA 548ab) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AB Gene

Genomics for MIR548AB Gene

Genomic Location for MIR548AB Gene

Start:
103,524,033 bp from pter
End:
103,524,116 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR548AB Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548AB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AB Gene

ORGUL Member Location for MIR548AB Gene

ORGUL Member Location for MIR548AB gene

No data available for Regulatory Elements for MIR548AB Gene

Proteins for MIR548AB Gene

Post-translational modifications for MIR548AB Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AB Gene

Domains for MIR548AB Gene

Gene Families for MIR548AB Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AB: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AB Gene

Function for MIR548AB Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR548AB Gene

Localization for MIR548AB Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AB Gene

Pathways for MIR548AB Gene

SuperPathways for MIR548AB Gene

No Data Available

Interacting Proteins for MIR548AB Gene

Gene Ontology (GO) - Biological Process for MIR548AB Gene

None

No data available for Pathways by source for MIR548AB Gene

Transcripts for MIR548AB Gene

mRNA/cDNA for MIR548AB Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AB Gene

No ASD Table

Relevant External Links for MIR548AB Gene

GeneLoc Exon Structure for
MIR548AB
ECgene alternative splicing isoforms for
MIR548AB

Expression for MIR548AB Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR548AB Gene

Orthologs for MIR548AB Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AB Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
OneToOne
Species with no ortholog for MIR548AB:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AB Gene

ENSEMBL:
Gene Tree for MIR548AB (if available)
TreeFam:
Gene Tree for MIR548AB (if available)

Paralogs for MIR548AB Gene

No data available for Paralogs for MIR548AB Gene

Variants for MIR548AB Gene

Sequence variations from dbSNP and Humsavar for MIR548AB Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs34391870 -- 103,524,548(+) TCAAA(-/A)GAAAT upstream-variant-2KB
rs59323834 -- 103,524,093(+) AAAAT(C/T)CACAA nc-transcript-variant
rs72364440 -- 103,524,328(+) TAGAC(-/TA)TGTGT upstream-variant-2KB
rs72957904 -- 103,524,023(+) ACATG(C/T)TTTCT downstream-variant-500B
rs72957905 -- 103,524,663(+) TATGC(A/T)GGCAG upstream-variant-2KB

Relevant External Links for MIR548AB Gene

HapMap Linkage Disequilibrium report
MIR548AB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR548AB Gene

Disorders for MIR548AB Gene

No disorders were found for MIR548AB Gene.

No data available for UniProtKB/Swiss-Prot for MIR548AB Gene

Publications for MIR548AB Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima D.D. … Dave S.S. (Blood 2010) 3

Products for MIR548AB Gene

Sources for MIR548AB Gene

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