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Aliases for MIR548AA1 Gene

Subcategory (RNA class) for MIR548AA1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR548AA1 Gene

  • MicroRNA 548aa-1 2 3 5
  • Hsa-Mir-548aa-1 3

External Ids for MIR548AA1 Gene

Previous GeneCards Identifiers for MIR548AA1 Gene

  • GC08U901479
  • GC08P124361

Summaries for MIR548AA1 Gene

Entrez Gene Summary for MIR548AA1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548AA1 Gene

MIR548AA1 (MicroRNA 548aa-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548AA1 Gene

Genomics for MIR548AA1 Gene

Regulatory Elements for MIR548AA1 Gene

Enhancers for MIR548AA1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F123374 0.7 ENCODE 12.3 +26.6 26570 1.1 SOX13 TFAP4 SAP130 CEBPG RARA TEAD3 CREM ZNF652 GATAD2A SOX5 DUTP2 MIR548AA1 RNU6-875P GC08M123342 IMPDH1P6
GH08F123386 1 Ensembl ENCODE 11.6 +39.2 39167 2.4 OSR2 IRF2 GATA3 MTA2 IKZF1 EBF1 IRF1 PRDM1 SPI1 WDYHV1 DUTP2 MIR548AA1 RNU6-875P ATAD2 FAM91A1 IMPDH1P6 GC08M123342
GH08F123285 0.2 ENCODE 11.3 -62.0 -62049 0.2 OSR2 JUND ZNF354C FOS ZNF600 PRDM10 KLF8 TRIM28 RNU6-628P RNU6-875P MIR548AA1 DUTP2 FAM83A KLHL38 FAM83A-AS1 LOC392266 ZHX1
GH08F123407 0.2 Ensembl 10.7 +59.9 59867 0.2 ZFP69B ZNF692 CEBPB MIR548AA1 DUTP2 RNU6-875P FBXO32 GC08M123406 ATAD2
GH08F123271 0.6 ENCODE 10.5 -74.2 -74162 4.3 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF766 RNU6-875P MIR548AA1 DUTP2 FAM83A ZHX1-C8orf76 RNU6-628P
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR548AA1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548AA1 Gene

Chromosome:
8
Start:
123,348,034 bp from pter
End:
123,348,130 bp from pter
Size:
97 bases
Orientation:
Plus strand

Genomic View for MIR548AA1 Gene

Genes around MIR548AA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548AA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548AA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548AA1 Gene

Proteins for MIR548AA1 Gene

Post-translational modifications for MIR548AA1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548AA1 Gene

Domains & Families for MIR548AA1 Gene

Gene Families for MIR548AA1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548AA1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548AA1 Gene

Function for MIR548AA1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548AA1 Gene

Localization for MIR548AA1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548AA1 Gene

Pathways & Interactions for MIR548AA1 Gene

SuperPathways for MIR548AA1 Gene

No Data Available

Interacting Proteins for MIR548AA1 Gene

Gene Ontology (GO) - Biological Process for MIR548AA1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR548AA1 Gene

Transcripts for MIR548AA1 Gene

mRNA/cDNA for MIR548AA1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548AA1 Gene

No ASD Table

Relevant External Links for MIR548AA1 Gene

GeneLoc Exon Structure for
MIR548AA1
ECgene alternative splicing isoforms for
MIR548AA1

Expression for MIR548AA1 Gene

mRNA expression in normal human tissues for MIR548AA1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548AA1 Gene:

MIR548AA1
genes like me logo Genes that share expression patterns with MIR548AA1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548AA1 Gene

Orthologs for MIR548AA1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548AA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 85 (a)
ManyToMany
Species where no ortholog for MIR548AA1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548AA1 Gene

ENSEMBL:
Gene Tree for MIR548AA1 (if available)
TreeFam:
Gene Tree for MIR548AA1 (if available)

Paralogs for MIR548AA1 Gene

No data available for Paralogs for MIR548AA1 Gene

Variants for MIR548AA1 Gene

Sequence variations from dbSNP and Humsavar for MIR548AA1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs111717669 -- 123,347,200(+) GGTGG(A/G)CAGTG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs111884296 -- 123,346,197(+) AAGTG(A/G)GAACC nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs112092597 -- 123,348,566(+) CAGCT(A/T)CTTGG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112283918 -- 123,347,313(+) GCAGT(G/T)TCTCA nc-transcript-variant, upstream-variant-2KB, reference, missense
rs113587862 -- 123,348,609(+) GGGAC(A/G)GAAGT intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548AA1 Gene

Variant ID Type Subtype PubMed ID
nsv831449 CNV loss 17160897

Relevant External Links for MIR548AA1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR548AA1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548AA1 Gene

Disorders for MIR548AA1 Gene

Relevant External Links for MIR548AA1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR548AA1

No disorders were found for MIR548AA1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548AA1 Gene

Publications for MIR548AA1 Gene

  1. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR548AA1 Gene

Sources for MIR548AA1 Gene

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