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Aliases for MIR548A3 Gene

Subcategory (RNA class) for MIR548A3 Gene


Quality Score for this RNA gene is


Aliases for MIR548A3 Gene

  • MicroRNA 548a-3 2 3
  • Hsa-Mir-548a-3 3
  • MIRN548A3 3

External Ids for MIR548A3 Gene

Previous HGNC Symbols for MIR548A3 Gene

  • MIRN548A3

Previous GeneCards Identifiers for MIR548A3 Gene

  • GC08M105566
  • GC08M105496

Summaries for MIR548A3 Gene

Entrez Gene Summary for MIR548A3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548A3 Gene

MIR548A3 (MicroRNA 548a-3) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR548A3 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR548A3

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR548A3 Gene

Genomics for MIR548A3 Gene

Genomic Location for MIR548A3 Gene

104,484,369 bp from pter
104,484,465 bp from pter
97 bases
Minus strand

Genomic View for MIR548A3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR548A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548A3 Gene

ORGUL Member Location for MIR548A3 Gene

ORGUL Member Location for MIR548A3 gene

No data available for Regulatory Elements for MIR548A3 Gene

Proteins for MIR548A3 Gene

Post-translational modifications for MIR548A3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548A3 Gene

Domains & Families for MIR548A3 Gene

Gene Families for MIR548A3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548A3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548A3 Gene

Function for MIR548A3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548A3 Gene

Localization for MIR548A3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548A3 Gene

Pathways & Interactions for MIR548A3 Gene

SuperPathways for MIR548A3 Gene

No Data Available

Interacting Proteins for MIR548A3 Gene

Gene Ontology (GO) - Biological Process for MIR548A3 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548A3 Gene

Drugs & Compounds for MIR548A3 Gene

No Compound Related Data Available

Transcripts for MIR548A3 Gene

fRNAdb Secondary structures for MIR548A3 Gene

  • hsa-mir-548a-3_MI0003612_Homo_sapiens_miR-548a-3_stem-loop_hairpin

mRNA/cDNA for MIR548A3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548A3 Gene

No ASD Table

Relevant External Links for MIR548A3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548A3 Gene

mRNA expression in normal human tissues for MIR548A3 Gene

genes like me logo Genes that share expression patterns with MIR548A3: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR548A3 Gene

Orthologs for MIR548A3 Gene

Evolution for MIR548A3 Gene

Gene Tree for MIR548A3 (if available)
Gene Tree for MIR548A3 (if available)

No data available for Orthologs for MIR548A3 Gene

Paralogs for MIR548A3 Gene

No data available for Paralogs for MIR548A3 Gene

Variants for MIR548A3 Gene

Sequence variations from dbSNP and Humsavar for MIR548A3 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs73293281 -- 104,485,459(+) TATGT(C/T)TGTTA upstream-variant-2KB
rs73293282 -- 104,486,396(+) TTATA(C/G)AACTT upstream-variant-2KB
rs74835137 -- 104,485,458(+) CTATG(C/T)CTGTT upstream-variant-2KB
rs76217708 -- 104,486,157(+) GAAGA(C/T)CTAAA upstream-variant-2KB
rs137871888 -- 104,485,956(+) GTGAG(A/G)ATTAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR548A3 Gene

Variant ID Type Subtype PubMed ID
nsv527886 CNV Loss 19592680
nsv10297 CNV Gain 18304495
nsv877272 CNV Loss 21882294
esv2664175 CNV Deletion 23128226

Relevant External Links for MIR548A3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548A3 Gene

Disorders for MIR548A3 Gene

Relevant External Links for MIR548A3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR548A3: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548A3 Gene

Publications for MIR548A3 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 1 67
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 67
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67

Products for MIR548A3 Gene

Sources for MIR548A3 Gene

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