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Aliases for MIR548A3 Gene

Subcategory (RNA class) for MIR548A3 Gene


Quality Score for this RNA gene is


Aliases for MIR548A3 Gene

  • MicroRNA 548a-3 2 3 5
  • Hsa-Mir-548a-3 3
  • MIRN548A3 3

External Ids for MIR548A3 Gene

Previous HGNC Symbols for MIR548A3 Gene

  • MIRN548A3

Previous GeneCards Identifiers for MIR548A3 Gene

  • GC08M105566
  • GC08M105496

Summaries for MIR548A3 Gene

Entrez Gene Summary for MIR548A3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548A3 Gene

MIR548A3 (MicroRNA 548a-3) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR548A3 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR548A3

Additional gene information for MIR548A3 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR548A3 Gene

Genomics for MIR548A3 Gene

GeneHancer (GH) Regulatory Elements for MIR548A3 Gene

Promoters and enhancers for MIR548A3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I104459 Enhancer 0.5 ENCODE 10.7 +24.0 23950 1.7 ZNF217 FOSL2 HNF4A YY1 MIR548A3 LRP12 DPYS LOC105375691 LOC105375692
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR548A3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR548A3 Gene

Genomic Locations for MIR548A3 Gene
97 bases
Minus strand

Genomic View for MIR548A3 Gene

Genes around MIR548A3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548A3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548A3 Gene

ORGUL Member Location for MIR548A3 Gene

ORGUL Member Location for MIR548A3 gene

Proteins for MIR548A3 Gene

Post-translational modifications for MIR548A3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548A3 Gene

Domains & Families for MIR548A3 Gene

Gene Families for MIR548A3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548A3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548A3 Gene

Function for MIR548A3 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548A3 Gene

Localization for MIR548A3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR548A3 Gene

Pathways & Interactions for MIR548A3 Gene

SuperPathways for MIR548A3 Gene

No Data Available

Interacting Proteins for MIR548A3 Gene

Gene Ontology (GO) - Biological Process for MIR548A3 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548A3 Gene

Drugs & Compounds for MIR548A3 Gene

No Compound Related Data Available

Transcripts for MIR548A3 Gene

fRNAdb Secondary structures for MIR548A3 Gene

  • hsa-mir-548a-3_MI0003612_Homo_sapiens_miR-548a-3_stem-loop_hairpin

mRNA/cDNA for MIR548A3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548A3 Gene

No ASD Table

Relevant External Links for MIR548A3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548A3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR548A3 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548A3 Gene:

genes like me logo Genes that share expression patterns with MIR548A3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR548A3 Gene

Orthologs for MIR548A3 Gene

Evolution for MIR548A3 Gene

Gene Tree for MIR548A3 (if available)
Gene Tree for MIR548A3 (if available)

No data available for Orthologs for MIR548A3 Gene

Paralogs for MIR548A3 Gene

No data available for Paralogs for MIR548A3 Gene

Variants for MIR548A3 Gene

Sequence variations from dbSNP and Humsavar for MIR548A3 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000523222 -- 104,486,464(-) T/C upstream_transcript_variant
rs1000841239 -- 104,484,464(-) G/C non_coding_transcript_variant
rs1000912830 -- 104,485,005(-) T/C upstream_transcript_variant
rs1002310423 -- 104,485,938(-) G/A upstream_transcript_variant
rs1004023305 -- 104,486,010(-) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR548A3 Gene

Variant ID Type Subtype PubMed ID
nsv831417 CNV loss 17160897

Additional Variant Information for MIR548A3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR548A3 Gene

Disorders for MIR548A3 Gene

Additional Disease Information for MIR548A3

No disorders were found for MIR548A3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548A3 Gene

Publications for MIR548A3 Gene

  1. The colorectal microRNAome. (PMID: 16505370) Cummins JM … Velculescu VE (Proceedings of the National Academy of Sciences of the United States of America 2006) 1 3 58
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR548A3 Gene

Sources for MIR548A3 Gene

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