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Aliases for MIR548A2 Gene

Subcategory (RNA class) for MIR548A2 Gene


Quality Score for this RNA gene is


Aliases for MIR548A2 Gene

  • MicroRNA 548a-2 2 3 5
  • Hsa-Mir-548a-2 3
  • MIRN548A2 3

External Ids for MIR548A2 Gene

ORGUL Members for MIR548A2 Gene

Previous HGNC Symbols for MIR548A2 Gene

  • MIRN548A2

Previous GeneCards Identifiers for MIR548A2 Gene

  • GC06P135602
  • GC06P135560

Summaries for MIR548A2 Gene

Entrez Gene Summary for MIR548A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR548A2 Gene

MIR548A2 (MicroRNA 548a-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR548A2 Gene

Genomics for MIR548A2 Gene

Regulatory Elements for MIR548A2 Gene

Enhancers for MIR548A2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F135319 1.6 FANTOM5 Ensembl ENCODE 11.3 +83.6 83640 7.3 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 CBX5 ZNF207 KLF13 JUNB REST AHI1 ENSG00000224374 MIR548A2 MYB BTRCP1 ENSG00000234084
GH06F135265 1 Ensembl ENCODE 11.7 +30.2 30207 6.8 TEAD4 CEBPG BMI1 POLR2A EED NR2F6 ZNF548 CREM ZNF652 RFX1 AHI1 ENSG00000234084 MIR548A2 MYB-AS1 MYB GC06P135267
GH06F135212 0.7 Ensembl 11.8 -26.3 -26260 1.0 ZNF362 PKNOX1 DPF2 POLR2H GATA3 ZNF316 POLR2A PBX2 FOS FOXP2 MIR548A2 ENSG00000224374 GC06P135201 LOC105378011
GH06F135250 1.1 Ensembl ENCODE 0.4 +12.7 12664 3.2 ELF3 THRB RARA YY1 CREM CEBPB PPARG MBD2 MIER3 CEBPA ENSG00000234084 AHI1 MYB-AS1 MYB ENSG00000224374 MIR548A2
GH06F135254 0.7 ENCODE 0.3 +15.5 15510 0.1 ZNF687 CEBPB MAFG DPF2 CEBPG ZNF217 MBD2 ZNF316 GATA3 CTBP1 MYB-AS1 MYB ENSG00000224374 MIR548A2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR548A2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR548A2 Gene

135,239,160 bp from pter
135,239,256 bp from pter
97 bases
Plus strand

Genomic View for MIR548A2 Gene

Genes around MIR548A2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR548A2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR548A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR548A2 Gene

Proteins for MIR548A2 Gene

Post-translational modifications for MIR548A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR548A2 Gene

Domains & Families for MIR548A2 Gene

Gene Families for MIR548A2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR548A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR548A2 Gene

Function for MIR548A2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR548A2 Gene

Localization for MIR548A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR548A2 Gene

Pathways & Interactions for MIR548A2 Gene

SuperPathways for MIR548A2 Gene

No Data Available

Interacting Proteins for MIR548A2 Gene

Gene Ontology (GO) - Biological Process for MIR548A2 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR548A2 Gene

Transcripts for MIR548A2 Gene

mRNA/cDNA for MIR548A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR548A2 Gene

No ASD Table

Relevant External Links for MIR548A2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR548A2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR548A2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR548A2 Gene:

genes like me logo Genes that share expression patterns with MIR548A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR548A2 Gene

Orthologs for MIR548A2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR548A2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-548a-2 35
  • 97 (a)
Species where no ortholog for MIR548A2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR548A2 Gene

Gene Tree for MIR548A2 (if available)
Gene Tree for MIR548A2 (if available)

Paralogs for MIR548A2 Gene

No data available for Paralogs for MIR548A2 Gene

Variants for MIR548A2 Gene

Sequence variations from dbSNP and Humsavar for MIR548A2 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs111292439 -- 135,238,045(+) TAATT(-/A)TAAAA upstream-variant-2KB
rs112531657 -- 135,237,170(+) AGGCA(C/T)GTGCT upstream-variant-2KB
rs116751958 -- 135,238,077(+) TCCAA(C/T)GGTCC upstream-variant-2KB
rs138594302 -- 135,238,322(+) AGAGA(C/T)GGCAT upstream-variant-2KB
rs139497303 -- 135,238,601(+) AAAAC(A/G)TCTAA upstream-variant-2KB

Relevant External Links for MIR548A2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR548A2 Gene

Disorders for MIR548A2 Gene

Relevant External Links for MIR548A2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR548A2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR548A2 Gene

Publications for MIR548A2 Gene

  1. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. (PMID: 25187353) Goldstein J.I. … Sullivan P.F. (Nat Commun 2014) 3 64
  2. White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder. (PMID: 23218918) Sprooten E. … McIntosh A.M. (Psychiatry Res 2013) 3 64
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64
  5. The colorectal microRNAome. (PMID: 16505370) Cummins J.M. … Velculescu V.E. (Proc. Natl. Acad. Sci. U.S.A. 2006) 3 64

Products for MIR548A2 Gene

Sources for MIR548A2 Gene

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