Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR544A Gene

Subcategory (RNA class) for MIR544A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR544A Gene

  • MicroRNA 544a 2 3 5
  • MicroRNA 544 2 3
  • Hsa-Mir-544a 3
  • Hsa-Mir-544 3
  • MIRN544 3
  • MIR544 3

External Ids for MIR544A Gene

ORGUL Members for MIR544A Gene

Previous HGNC Symbols for MIR544A Gene

  • MIRN544
  • MIR544

Previous GeneCards Identifiers for MIR544A Gene

  • GC14P101746
  • GC14P101785
  • GC14P101846
  • GC14P101987
  • GC14P102185
  • GC14P101260
  • GC14P101871
  • GC14P102190
  • GC14P102359
  • GC14P102530
  • GC14P102709
  • GC14P102882

Summaries for MIR544A Gene

Entrez Gene Summary for MIR544A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR544A Gene

MIR544A (MicroRNA 544a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR544A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR544A Gene

Genomics for MIR544A Gene

GeneHancer (GH) Regulatory Elements for MIR544A Gene

Promoters and enhancers for MIR544A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I101287 Enhancer 0.9 ENCODE 9.4 +240.3 240263 2.5 FOXA2 MLX ZFP64 ARID4B ZNF48 ETS1 YY1 RXRA SP5 NFYC MEG3 MIR1185-2 MIR381 MIR487B MIR539 MIR544A MIR889 MIR655 MIR1185-1 MIR300
GH14I101333 Enhancer 0.9 ENCODE 8.9 +286.4 286399 2.2 ELF3 FOXA2 ARID4B ZSCAN9 RAD21 RARA YY1 CREM THAP11 MIXL1 ENSG00000258460 GC14M101304 MIR381 MIR487B MIR539 MIR544A MIR655 MIR889 MIR376C MIR1185-1
GH14I101215 Enhancer 0.8 ENCODE 9.9 +168.1 168066 2.8 FOXA2 ARID4B RAD21 ZNF48 ZSCAN9 RARA CREM RXRA CEBPB NR2F2 LOC100128373 SNORD113-3 SNORD113-4 SNORD113-6 SNORD113-7 SNORD113-8 SNORD113-9 MIR543 ENSG00000222185 ENSG00000222095
GH14I101004 Enhancer 0.7 Ensembl ENCODE 10.9 -43.6 -43573 1.9 GATA3 MNT MYC TCF7L2 MIR134 MIR487A MIR154 MIR323B MIR485 MIR377 MIR496 MIR376C MIR1185-1 MIR1185-2
GH14I101096 Enhancer 0.7 FANTOM5 ENCODE 10.7 +49.7 49690 3.2 ATF4 POLR2A JUN MAFK RTL1 LOC105370670 MEG9 MIR369 MIR409 MIR410 MIR412 MIR541 MIR656 MIR154
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR544A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR544A Gene

Genomic Locations for MIR544A Gene
chr14:101,048,658-101,048,748
(GRCh38/hg38)
Size:
91 bases
Orientation:
Plus strand
chr14:101,514,995-101,515,085
(GRCh37/hg19)

Genomic View for MIR544A Gene

Genes around MIR544A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR544A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR544A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR544A Gene

Proteins for MIR544A Gene

Post-translational modifications for MIR544A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR544A Gene

Domains & Families for MIR544A Gene

Gene Families for MIR544A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR544A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR544A Gene

Function for MIR544A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR544A Gene

Localization for MIR544A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR544A Gene

Pathways & Interactions for MIR544A Gene

SuperPathways for MIR544A Gene

No Data Available

Interacting Proteins for MIR544A Gene

Gene Ontology (GO) - Biological Process for MIR544A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR544A Gene

Drugs & Compounds for MIR544A Gene

No Compound Related Data Available

Transcripts for MIR544A Gene

mRNA/cDNA for MIR544A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR544A Gene

No ASD Table

Relevant External Links for MIR544A Gene

GeneLoc Exon Structure for
MIR544A
ECgene alternative splicing isoforms for
MIR544A

Expression for MIR544A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR544A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR544A Gene:

MIR544A
genes like me logo Genes that share expression patterns with MIR544A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR544A Gene

Orthologs for MIR544A Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR544A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-544 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-544a 34
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-544 34
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir544 34
  • 95 (a)
OneToOne
Species where no ortholog for MIR544A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR544A Gene

ENSEMBL:
Gene Tree for MIR544A (if available)
TreeFam:
Gene Tree for MIR544A (if available)

Paralogs for MIR544A Gene

No data available for Paralogs for MIR544A Gene

Variants for MIR544A Gene

Sequence variations from dbSNP and Humsavar for MIR544A Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1001499669 -- 101,048,356(+) A/G upstream_transcript_variant
rs1002444581 -- 101,046,676(+) T/C upstream_transcript_variant
rs1005375970 -- 101,048,031(+) C/T upstream_transcript_variant
rs1006688709 -- 101,047,488(+) G/C upstream_transcript_variant
rs1006923333 -- 101,047,203(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR544A Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR544A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR544A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR544A Gene

Disorders for MIR544A Gene

Additional Disease Information for MIR544A

No disorders were found for MIR544A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR544A Gene

Publications for MIR544A Gene

  1. miR-544a Promotes Breast Cancer Cell Migration and Invasion Reducing Cadherin 1 Expression. (PMID: 27053345) Lu P … Qiu X (Oncology research 2016) 3 58
  2. MicroRNA-544a Regulates Migration and Invasion in Colorectal Cancer Cells via Regulation of Homeobox A10. (PMID: 27165435) Sun S … Lv Y (Digestive diseases and sciences 2016) 3 58
  3. MicroRNA-544 down-regulates both Bcl6 and Stat3 to inhibit tumor growth of human triple negative breast cancer. (PMID: 27186677) Zhu Z … Huang J (Biological chemistry 2016) 3 58
  4. Human MiR-544a Modulates SELK Expression in Hepatocarcinoma Cell Lines. (PMID: 27275761) Potenza N … Costantini S (PloS one 2016) 3 58
  5. miR-544a induces epithelial-mesenchymal transition through the activation of WNT signaling pathway in gastric cancer. (PMID: 26264654) Yanaka Y … Inazawa J (Carcinogenesis 2015) 3 58

Products for MIR544A Gene

Sources for MIR544A Gene

Content
Loading form....