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Aliases for MIR542 Gene

Subcategory (RNA class) for MIR542 Gene


Quality Score for this RNA gene is


Aliases for MIR542 Gene

  • MicroRNA 542 2 3
  • Hsa-Mir-542 3
  • Mir-542 3
  • MIRN542 3

External Ids for MIR542 Gene

Previous HGNC Symbols for MIR542 Gene

  • MIRN542

Previous GeneCards Identifiers for MIR542 Gene

  • GC0XM133519
  • GC0XM133528
  • GC0XM133678
  • GC0XM133684
  • GC0XM133695
  • GC0XM133712
  • GC0XM134544

Summaries for MIR542 Gene

Entrez Gene Summary for MIR542 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR542 Gene

MIR542 (MicroRNA 542) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are miRNAs involved in DDR.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR542 Gene

Genomics for MIR542 Gene

Genomic Location for MIR542 Gene

134,541,341 bp from pter
134,541,455 bp from pter
115 bases
Minus strand

Genomic View for MIR542 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR542 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR542 Gene

No data available for Regulatory Elements for MIR542 Gene

Proteins for MIR542 Gene

Post-translational modifications for MIR542 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR542 Gene

Domains & Families for MIR542 Gene

Gene Families for MIR542 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR542: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR542 Gene

Function for MIR542 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR542 Gene

Localization for MIR542 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR542 Gene

Pathways & Interactions for MIR542 Gene

SuperPathways for MIR542 Gene

Superpath Contained pathways
1 miRNAs involved in DDR
genes like me logo Genes that share pathways with MIR542: view

Pathways by source for MIR542 Gene

1 BioSystems pathway for MIR542 Gene

Interacting Proteins for MIR542 Gene

Gene Ontology (GO) - Biological Process for MIR542 Gene


No data available for SIGNOR curated interactions for MIR542 Gene

Drugs & Compounds for MIR542 Gene

No Compound Related Data Available

Transcripts for MIR542 Gene

mRNA/cDNA for MIR542 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR542 Gene

No ASD Table

Relevant External Links for MIR542 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR542 Gene

mRNA expression in normal human tissues for MIR542 Gene

genes like me logo Genes that share expression patterns with MIR542: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR542 Gene

Orthologs for MIR542 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR542 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-542 36
  • 92 (a)
(Canis familiaris)
Mammalia cfa-mir-542 36
  • 63 (a)
(Mus musculus)
Mammalia Mir542 36
  • 95 (a)
Species with no ortholog for MIR542:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR542 Gene

Gene Tree for MIR542 (if available)
Gene Tree for MIR542 (if available)

Paralogs for MIR542 Gene

No data available for Paralogs for MIR542 Gene

Variants for MIR542 Gene

Sequence variations from dbSNP and Humsavar for MIR542 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs3021371 -- 134,542,789(+) GGAGG(A/G)AAAAG upstream-variant-2KB
rs112553072 -- 134,542,666(+) GCCCA(A/G)GCAAC upstream-variant-2KB
rs188481291 -- 134,542,693(+) CTTTC(A/G)GGGCT upstream-variant-2KB
rs190827268 -- 134,542,830(+) CTAGC(A/C)GATCC upstream-variant-2KB
rs762307639 -- 134,542,786(+) GGAGG(A/T)GGGAA upstream-variant-2KB

Relevant External Links for MIR542 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR542 Gene

Disorders for MIR542 Gene

Relevant External Links for MIR542

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR542: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR542 Gene

Publications for MIR542 Gene

  1. miRa89542a893p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogha89like 2. (PMID: 25352048) Li H. … Lv H. (Mol Med Rep 2015) 67
  2. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin. (PMID: 25046253) Althoff K. … Schulte J.H. (Int. J. Cancer 2015) 67
  3. p53 is positively regulated by miR-542-3p. (PMID: 24762395) Wang Y. … Taniguchi T. (Cancer Res. 2014) 67
  4. MicroRNA-542-3p inhibits tumour angiogenesis by targeting angiopoietin-2. (PMID: 24403060) He T. … Luo Y. (J. Pathol. 2014) 67
  5. Circulating microRNAs identified in a genome-wide serum microRNA expression analysis as noninvasive biomarkers for endometriosis. (PMID: 23118427) Wang W.T. … Chen Y.Q. (J. Clin. Endocrinol. Metab. 2013) 67

Products for MIR542 Gene

Sources for MIR542 Gene

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