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Aliases for MIR541 Gene

Subcategory (RNA class) for MIR541 Gene

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Quality Score for this RNA gene is

3

Aliases for MIR541 Gene

  • MicroRNA 541 2 3
  • Hsa-Mir-541 3
  • MIRN541 3

External Ids for MIR541 Gene

ORGUL Members for MIR541 Gene

Previous Symbols for MIR541 Gene

  • MIRN541

Summaries for MIR541 Gene

Entrez Gene Summary for MIR541 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR541 Gene

MIR541 (MicroRNA 541) is a RNA Gene, and belongs to undefined RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR541 Gene

Genomics for MIR541 Gene

Genomic Location for MIR541 Gene

Start:
101,064,495 bp from pter
End:
101,064,578 bp from pter
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR541 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR541 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR541 Gene

No data available for Regulatory Elements for MIR541 Gene

Proteins for MIR541 Gene

Post-translational modifications for MIR541 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR541 Gene

Domains for MIR541 Gene

Gene Families for MIR541 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR541: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR541 Gene

Function for MIR541 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR541 Gene

Localization for MIR541 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR541 Gene

Pathways for MIR541 Gene

SuperPathways for MIR541 Gene

No Data Available

Interacting Proteins for MIR541 Gene

Gene Ontology (GO) - Biological Process for MIR541 Gene

None

No data available for Pathways by source for MIR541 Gene

Transcripts for MIR541 Gene

mRNA/cDNA for MIR541 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR541 Gene

No ASD Table

Relevant External Links for MIR541 Gene

GeneLoc Exon Structure for
MIR541
ECgene alternative splicing isoforms for
MIR541

Expression for MIR541 Gene

mRNA expression in normal human tissues for MIR541 Gene

genes like me logo Genes that share expressions with MIR541: view

Orthologs for MIR541 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR541 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 70 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-541 37
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir541 37
  • 69 (a)
OneToOne
Species with no ortholog for MIR541:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR541 Gene

ENSEMBL:
Gene Tree for MIR541 (if available)
TreeFam:
Gene Tree for MIR541 (if available)

Paralogs for MIR541 Gene

No data available for Paralogs for MIR541 Gene

Variants for MIR541 Gene

Sequence variations from dbSNP and Humsavar for MIR541 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs4906033 -- 101,063,077(+) TATCA(A/G)TGTTG upstream-variant-2KB
rs4906034 -- 101,063,100(+) TGAAG(A/G)TGGTT upstream-variant-2KB
rs7161194 -- 101,062,668(+) TGATA(A/G)AAATA upstream-variant-2KB
rs8003403 -- 101,062,976(+) AATAA(A/G)AGAAA upstream-variant-2KB
rs8023048 -- 101,062,805(+) AATAG(A/C)AAGCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR541 Gene

Variant ID Type Subtype PubMed ID
nsv509551 CNV Insertion 20534489

Relevant External Links for MIR541 Gene

HapMap Linkage Disequilibrium report
MIR541

Disorders for MIR541 Gene

No disorders were found for MIR541 Gene.

No data available for UniProtKB/Swiss-Prot for MIR541 Gene

Publications for MIR541 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  3. miRNA analysis in vitreous humor to determine the time of death: a proof-of-concept pilot study. (PMID: 23254460) Odriozola A. … Zarrabeitia M.T. (Int. J. Legal Med. 2013) 3
  4. OstemiR: a novel panel of microRNA biomarkers in osteoblastic and osteocytic differentiation from mesencymal stem cells. (PMID: 23533592) Eguchi T. … Calderwood S.K. (PLoS ONE 2013) 3

Products for MIR541 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR541
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR541
    • Block miRNA regulation of MIR541 using miScript Target Protectors

    Sources for MIR541 Gene

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