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Aliases for MIR532 Gene

Subcategory (RNA class) for MIR532 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR532 Gene

  • MicroRNA 532 2 3 5
  • Hsa-Mir-532 3
  • Mir-532 3
  • MIRN532 3

External Ids for MIR532 Gene

ORGUL Members for MIR532 Gene

Previous HGNC Symbols for MIR532 Gene

  • MIRN532

Previous GeneCards Identifiers for MIR532 Gene

  • GC0XP049656
  • GC0XP049767

Summaries for MIR532 Gene

Entrez Gene Summary for MIR532 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR532 Gene

MIR532 (MicroRNA 532) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR532 Gene

Genomics for MIR532 Gene

Regulatory Elements for MIR532 Gene

Enhancers for MIR532 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF050034 0.2 ENCODE 13.7 +32.8 32802 2.3 MIR362 MIR500A MIR500B MIR501 MIR188 MIR532 CLCN5 GC0XP050030 PYY3
GH0XF049957 1.3 Ensembl ENCODE 12.5 -43.4 -43443 3.7 ZNF316 PKNOX1 MAFG NFE2 EMSY SPI1 MIR188 MIR532 MIR362 MIR500A MIR500B MIR501 CLCN5 GC0XM049946 GC0XP049999
GH0XF049976 0.5 Ensembl ENCODE 11.8 -24.8 -24791 3.0 ZFP64 ZNF140 ZNF266 FEZF1 ZNF354C POLR2A PRDM10 ZNF433 TCF7L2 ZNF202 ENSG00000270012 USP27X-AS1 MIR532 MIR188 MIR362 MIR500A MIR500B MIR501 PRAF2 CLCN5
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR532 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR532 Gene

Chromosome:
X
Start:
50,003,148 bp from pter
End:
50,003,238 bp from pter
Size:
91 bases
Orientation:
Plus strand

Genomic View for MIR532 Gene

Genes around MIR532 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR532 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR532 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR532 Gene

Proteins for MIR532 Gene

Post-translational modifications for MIR532 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR532 Gene

Domains & Families for MIR532 Gene

Gene Families for MIR532 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR532: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR532 Gene

Function for MIR532 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR532 Gene

Localization for MIR532 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR532 Gene

Pathways & Interactions for MIR532 Gene

SuperPathways for MIR532 Gene

No Data Available

Interacting Proteins for MIR532 Gene

Gene Ontology (GO) - Biological Process for MIR532 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR532 Gene

Transcripts for MIR532 Gene

mRNA/cDNA for MIR532 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR532 Gene

No ASD Table

Relevant External Links for MIR532 Gene

GeneLoc Exon Structure for
MIR532
ECgene alternative splicing isoforms for
MIR532

Expression for MIR532 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR532 Gene:

MIR532
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR532 Gene

Orthologs for MIR532 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR532 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia cfa-mir-532 35
  • 98 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-532 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-532 35
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir532 35
  • 84 (a)
OneToOne
Species where no ortholog for MIR532 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR532 Gene

ENSEMBL:
Gene Tree for MIR532 (if available)
TreeFam:
Gene Tree for MIR532 (if available)

Paralogs for MIR532 Gene

No data available for Paralogs for MIR532 Gene

Variants for MIR532 Gene

Sequence variations from dbSNP and Humsavar for MIR532 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs111705989 -- 50,002,739(+) AAAGT(G/T)GTTGG intron-variant, upstream-variant-2KB
rs112258907 -- 50,002,689(+) TCTCT(C/G)TGTGT intron-variant, upstream-variant-2KB
rs112819480 -- 50,002,619(+) CTCTT(G/T)CGTCT intron-variant, upstream-variant-2KB
rs113405602 -- 50,002,621(+) CTTGC(G/T)TCTGT intron-variant, upstream-variant-2KB
rs113620038 -- 50,002,620(+) TCTTG(A/C)GTCTG intron-variant, upstream-variant-2KB

Relevant External Links for MIR532 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR532

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR532 Gene

Disorders for MIR532 Gene

Relevant External Links for MIR532

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR532

No disorders were found for MIR532 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR532 Gene

Publications for MIR532 Gene

  1. Human MicroRNA miR-532-5p Exhibits Antiviral Activity against West Nile Virus via Suppression of Host Genes SESTD1 and TAB3 Required for Virus Replication. (PMID: 26676784) Slonchak A. … Khromykh A.A. (J. Virol. 2016) 3 64
  2. A panel of microRNAs as a new biomarkers for the detection of deep vein thrombosis. (PMID: 25244974) Qin J. … Jiang Q. (J. Thromb. Thrombolysis 2015) 3 64
  3. microRNAome expression in chronic lymphocytic leukemia: comparison with normal B-cell subsets and correlations with prognostic and clinical parameters. (PMID: 24916701) Negrini M. … Neri A. (Clin. Cancer Res. 2014) 3 64
  4. Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets. (PMID: 25517766) Hall E. … Ling C. (Genome Biol. 2014) 3 64
  5. MicroRNA expression in ovarian carcinoma and its correlation with clinicopathological features. (PMID: 22925189) Lee H. … Feng Q. (World J Surg Oncol 2012) 3 64

Products for MIR532 Gene

Sources for MIR532 Gene

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