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Aliases for MIR527 Gene

Subcategory (RNA class) for MIR527 Gene


Quality Score for this RNA gene is


Aliases for MIR527 Gene

  • MicroRNA 527 2 3
  • Hsa-Mir-527 3
  • MIRN527 3

External Ids for MIR527 Gene

ORGUL Members for MIR527 Gene

Previous HGNC Symbols for MIR527 Gene

  • MIRN527

Previous GeneCards Identifiers for MIR527 Gene

  • GC19P058980
  • GC19P059023
  • GC19P054257

Summaries for MIR527 Gene

Entrez Gene Summary for MIR527 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR527 Gene

MIR527 (MicroRNA 527) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR527 Gene

Genomics for MIR527 Gene

Genomic Location for MIR527 Gene

53,754,018 bp from pter
53,754,102 bp from pter
85 bases
Plus strand

Genomic View for MIR527 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR527 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR527 Gene

No data available for Regulatory Elements for MIR527 Gene

Proteins for MIR527 Gene

Post-translational modifications for MIR527 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR527 Gene

Domains for MIR527 Gene

Gene Families for MIR527 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR527: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR527 Gene

Function for MIR527 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR527 Gene

Localization for MIR527 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR527 Gene

Pathways for MIR527 Gene

SuperPathways for MIR527 Gene

No Data Available

Interacting Proteins for MIR527 Gene

Gene Ontology (GO) - Biological Process for MIR527 Gene


No data available for Pathways by source for MIR527 Gene

Transcripts for MIR527 Gene

mRNA/cDNA for MIR527 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR527 Gene

No ASD Table

Relevant External Links for MIR527 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR527 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR527 Gene

Orthologs for MIR527 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR527 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-527 36
  • 97 (a)
Species with no ortholog for MIR527:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR527 Gene

Gene Tree for MIR527 (if available)
Gene Tree for MIR527 (if available)

Paralogs for MIR527 Gene

No data available for Paralogs for MIR527 Gene

Variants for MIR527 Gene

Sequence variations from dbSNP and Humsavar for MIR527 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs305938 -- 53,753,057(+) attac(A/T)ggcct upstream-variant-2KB
rs305939 -- 53,754,494(+) cccag(A/G)ctgga downstream-variant-500B
rs611356 -- 53,753,931(+) CAGGG(A/C/G)CAATA upstream-variant-2KB
rs611370 -- 53,753,937(+) CAATA(A/C)ATGCA upstream-variant-2KB
rs3859499 -- 53,753,860(+) ATTCT(C/T)TGAAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR527 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv912385 CNV Gain 21882294
dgv3999n71 CNV Gain 21882294
nsv458781 CNV Gain 19166990
esv2718833 CNV Deletion 23290073
esv2448351 CNV Deletion 19546169
esv2718841 CNV Deletion 23290073

Relevant External Links for MIR527 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR527 Gene

Disorders for MIR527 Gene

No disorders were found for MIR527 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR527 Gene

Publications for MIR527 Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR527 Gene

Sources for MIR527 Gene

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