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Aliases for MIR523 Gene

Subcategory (RNA class) for MIR523 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR523 Gene

  • MicroRNA 523 2 3
  • Hsa-Mir-523 3
  • AC011453.4 5
  • Mir-523 3
  • MIRN523 3

External Ids for MIR523 Gene

Previous HGNC Symbols for MIR523 Gene

  • MIRN523

Previous GeneCards Identifiers for MIR523 Gene

  • GC19P058900
  • GC19P058994
  • GC19P054201

Summaries for MIR523 Gene

Entrez Gene Summary for MIR523 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR523 Gene

MIR523 (MicroRNA 523) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR523 Gene

Genomics for MIR523 Gene

Genomic Location for MIR523 Gene

Chromosome:
19
Start:
53,698,371 bp from pter
End:
53,698,489 bp from pter
Size:
119 bases
Orientation:
Plus strand

Genomic View for MIR523 Gene

Genes around MIR523 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR523 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR523 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR523 Gene

No data available for Regulatory Elements for MIR523 Gene

Proteins for MIR523 Gene

Post-translational modifications for MIR523 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR523 Gene

Domains & Families for MIR523 Gene

Gene Families for MIR523 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR523: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR523 Gene

Function for MIR523 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR523 Gene

Localization for MIR523 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR523 Gene

Pathways & Interactions for MIR523 Gene

SuperPathways for MIR523 Gene

No Data Available

Interacting Proteins for MIR523 Gene

Gene Ontology (GO) - Biological Process for MIR523 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR523 Gene

Drugs & Compounds for MIR523 Gene

No Compound Related Data Available

Transcripts for MIR523 Gene

mRNA/cDNA for MIR523 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR523 Gene

No ASD Table

Relevant External Links for MIR523 Gene

GeneLoc Exon Structure for
MIR523
ECgene alternative splicing isoforms for
MIR523

Expression for MIR523 Gene

mRNA expression in normal human tissues for MIR523 Gene

genes like me logo Genes that share expression patterns with MIR523: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR523 Gene

Orthologs for MIR523 Gene

Evolution for MIR523 Gene

ENSEMBL:
Gene Tree for MIR523 (if available)
TreeFam:
Gene Tree for MIR523 (if available)

No data available for Orthologs for MIR523 Gene

Paralogs for MIR523 Gene

No data available for Paralogs for MIR523 Gene

Variants for MIR523 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR523 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv912385 CNV Gain 21882294
dgv3999n71 CNV Gain 21882294
nsv458781 CNV Gain 19166990
esv2718833 CNV Deletion 23290073

Relevant External Links for MIR523 Gene

HapMap Linkage Disequilibrium report
MIR523

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR523 Gene

Disorders for MIR523 Gene

Relevant External Links for MIR523

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR523

No disorders were found for MIR523 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR523 Gene

Publications for MIR523 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 67
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3

Products for MIR523 Gene

Sources for MIR523 Gene

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