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Aliases for MIR522 Gene

Subcategory (RNA class) for MIR522 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR522 Gene

  • MicroRNA 522 2 3 5
  • Hsa-Mir-522 3
  • Mir-522 3
  • MIRN522 3

External Ids for MIR522 Gene

ORGUL Members for MIR522 Gene

Previous HGNC Symbols for MIR522 Gene

  • MIRN522

Previous GeneCards Identifiers for MIR522 Gene

  • GC19P058978
  • GC19P059021
  • GC19P054254

Summaries for MIR522 Gene

Entrez Gene Summary for MIR522 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR522 Gene

MIR522 (MicroRNA 522) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR522 Gene

Genomics for MIR522 Gene

Genomic Location for MIR522 Gene

Chromosome:
19
Start:
53,751,197 bp from pter
End:
53,751,303 bp from pter
Size:
107 bases
Orientation:
Plus strand

Genomic View for MIR522 Gene

Genes around MIR522 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR522 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR522 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR522 Gene

No data available for Regulatory Elements for MIR522 Gene

Proteins for MIR522 Gene

Post-translational modifications for MIR522 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR522 Gene

Domains & Families for MIR522 Gene

Gene Families for MIR522 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR522: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR522 Gene

Function for MIR522 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR522 Gene

Localization for MIR522 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR522 Gene

Pathways & Interactions for MIR522 Gene

SuperPathways for MIR522 Gene

No Data Available

Interacting Proteins for MIR522 Gene

Gene Ontology (GO) - Biological Process for MIR522 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR522 Gene

Drugs & Compounds for MIR522 Gene

No Compound Related Data Available

Transcripts for MIR522 Gene

mRNA/cDNA for MIR522 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR522 Gene

No ASD Table

Relevant External Links for MIR522 Gene

GeneLoc Exon Structure for
MIR522
ECgene alternative splicing isoforms for
MIR522

Expression for MIR522 Gene

mRNA expression in normal human tissues for MIR522 Gene

genes like me logo Genes that share expression patterns with MIR522: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR522 Gene

Orthologs for MIR522 Gene

Evolution for MIR522 Gene

ENSEMBL:
Gene Tree for MIR522 (if available)
TreeFam:
Gene Tree for MIR522 (if available)

No data available for Orthologs for MIR522 Gene

Paralogs for MIR522 Gene

No data available for Paralogs for MIR522 Gene

Variants for MIR522 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR522 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv912385 CNV Gain 21882294
dgv3999n71 CNV Gain 21882294
nsv458781 CNV Gain 19166990
esv2718833 CNV Deletion 23290073
esv2448351 CNV Deletion 19546169

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for MIR522 Gene

Disorders for MIR522 Gene

Relevant External Links for MIR522

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR522

No disorders were found for MIR522 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR522 Gene

Publications for MIR522 Gene

  1. MiR-522 contributes to cell proliferation of human glioblastoma cells by suppressing PHLPP1 expression. (PMID: 25776496) Zhang S. … Liu Y. (Biomed. Pharmacother. 2015) 3 67
  2. Sequencing of captive target transcripts identifies the network of regulated genes and functions of primate-specific miR-522. (PMID: 25131211) Tan S.M. … Lieberman J. (Cell Rep 2014) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  4. The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site. (PMID: 21533135) Richardson K. … Ordovas J.M. (PLoS ONE 2011) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR522 Gene

Sources for MIR522 Gene

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