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Aliases for MIR520F Gene

Subcategory (RNA class) for MIR520F Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR520F Gene

  • MicroRNA 520f 2 3 5
  • Hsa-Mir-520f 3
  • Mir-520f 3
  • MIRN520F 3

External Ids for MIR520F Gene

ORGUL Members for MIR520F Gene

Previous HGNC Symbols for MIR520F Gene

  • MIRN520F

Previous GeneCards Identifiers for MIR520F Gene

  • GC19P058879
  • GC19P054185

Summaries for MIR520F Gene

Entrez Gene Summary for MIR520F Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR520F Gene

MIR520F (MicroRNA 520f) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR520F Gene

Genomics for MIR520F Gene

Genomic Location for MIR520F Gene

Chromosome:
19
Start:
53,682,159 bp from pter
End:
53,682,260 bp from pter
Size:
102 bases
Orientation:
Plus strand

Genomic View for MIR520F Gene

Genes around MIR520F on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR520F Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR520F Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR520F Gene

No data available for Regulatory Elements for MIR520F Gene

Proteins for MIR520F Gene

Post-translational modifications for MIR520F Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR520F Gene

Domains & Families for MIR520F Gene

Gene Families for MIR520F Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR520F: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR520F Gene

Function for MIR520F Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR520F Gene

Localization for MIR520F Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR520F Gene

Pathways & Interactions for MIR520F Gene

SuperPathways for MIR520F Gene

No Data Available

Interacting Proteins for MIR520F Gene

Gene Ontology (GO) - Biological Process for MIR520F Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR520F Gene

Drugs & Compounds for MIR520F Gene

No Compound Related Data Available

Transcripts for MIR520F Gene

mRNA/cDNA for MIR520F Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR520F Gene

No ASD Table

Relevant External Links for MIR520F Gene

GeneLoc Exon Structure for
MIR520F
ECgene alternative splicing isoforms for
MIR520F

Expression for MIR520F Gene

mRNA expression in normal human tissues for MIR520F Gene

genes like me logo Genes that share expression patterns with MIR520F: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR520F Gene

Orthologs for MIR520F Gene

Evolution for MIR520F Gene

ENSEMBL:
Gene Tree for MIR520F (if available)
TreeFam:
Gene Tree for MIR520F (if available)

No data available for Orthologs for MIR520F Gene

Paralogs for MIR520F Gene

No data available for Paralogs for MIR520F Gene

Variants for MIR520F Gene

Sequence variations from dbSNP and Humsavar for MIR520F Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7250575 -- 53,681,321(+) CCCTC(C/T)TTAAG upstream-variant-2KB
rs6509808 -- 53,681,909(+) CTGGG(A/G)CTACA upstream-variant-2KB
rs7257490 -- 53,682,718(+) TTGAG(A/G)TGAAC downstream-variant-500B
rs7257574 -- 53,682,688(+) GCCAC(C/T)GCGCC downstream-variant-500B
rs7248919 -- 53,680,790(+) gtctc(A/G)aactc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR520F Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv912385 CNV Gain 21882294
dgv3999n71 CNV Gain 21882294
nsv458781 CNV Gain 19166990
esv2718833 CNV Deletion 23290073

Relevant External Links for MIR520F Gene

HapMap Linkage Disequilibrium report
MIR520F

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR520F Gene

Disorders for MIR520F Gene

Relevant External Links for MIR520F

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR520F

No disorders were found for MIR520F Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR520F Gene

Publications for MIR520F Gene

  1. Modulation of chemotherapeutic drug resistance in neuroblastoma SK-N-AS cells by the neural apoptosis inhibitory protein and miR-520f. (PMID: 25137037) Harvey H. … Bray I.M. (Int. J. Cancer 2015) 3 67
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3

Products for MIR520F Gene

Sources for MIR520F Gene

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