Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR520C Gene

Subcategory (RNA class) for MIR520C Gene


Quality Score for this RNA gene is


Aliases for MIR520C Gene

  • MicroRNA 520c 2 3
  • Hsa-Mir-520c 3
  • MIRN520C 3

External Ids for MIR520C Gene

ORGUL Members for MIR520C Gene

Previous HGNC Symbols for MIR520C Gene

  • MIRN520C

Previous GeneCards Identifiers for MIR520C Gene

  • GC19P058930
  • GC19P059001
  • GC19P054210

Summaries for MIR520C Gene

Entrez Gene Summary for MIR520C Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR520C Gene

MIR520C (MicroRNA 520c) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR520C Gene

Genomics for MIR520C Gene

Genomic Location for MIR520C Gene

53,707,453 bp from pter
53,707,539 bp from pter
87 bases
Plus strand

Genomic View for MIR520C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR520C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR520C Gene

No data available for Regulatory Elements for MIR520C Gene

Proteins for MIR520C Gene

Post-translational modifications for MIR520C Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR520C Gene

Domains for MIR520C Gene

Gene Families for MIR520C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR520C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR520C Gene

Function for MIR520C Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR520C Gene

Localization for MIR520C Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR520C Gene

Pathways for MIR520C Gene

SuperPathways for MIR520C Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR520C: view

Pathways by source for MIR520C Gene

1 KEGG pathway for MIR520C Gene

Interacting Proteins for MIR520C Gene

Gene Ontology (GO) - Biological Process for MIR520C Gene


Transcripts for MIR520C Gene

mRNA/cDNA for MIR520C Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR520C Gene

No ASD Table

Relevant External Links for MIR520C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR520C Gene

mRNA expression in normal human tissues for MIR520C Gene

genes like me logo Genes that share expressions with MIR520C: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR520C Gene

Orthologs for MIR520C Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR520C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-520c 36
  • 100 (a)
Species with no ortholog for MIR520C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR520C Gene

Gene Tree for MIR520C (if available)
Gene Tree for MIR520C (if available)

Paralogs for MIR520C Gene

No data available for Paralogs for MIR520C Gene

Variants for MIR520C Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR520C Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv912385 CNV Gain 21882294
dgv3999n71 CNV Gain 21882294
nsv458781 CNV Gain 19166990
esv2718833 CNV Deletion 23290073
esv2718836 CNV Deletion 23290073

Relevant External Links for MIR520C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR520C Gene

Disorders for MIR520C Gene

No disorders were found for MIR520C Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR520C Gene

Publications for MIR520C Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Down-regulation of eIF4GII by miR-520c-3p represses diffuse large B cell lymphoma development. (PMID: 24497838) Mazan-Mamczarz K. … Gartenhaus R.B. (PLoS Genet. 2014) 3
  5. MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-I_B and TGF-I^ signaling pathways. (PMID: 22158050) Keklikoglou I. … Tschulena U. (Oncogene 2012) 3

Products for MIR520C Gene

Sources for MIR520C Gene

Back to Top